Process Engineer, Purification - Lilly Medicine Foundry

Lilly Medicine Foundry Process Engineer

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Lilly recently announced a $4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

Lilly is currently constructing an advanced research facility for production of API molecules for clinical trials located in Lebanon, IN. This facility is Lilly's largest investment in a clinical trial manufacturing capacity and is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations.

We are seeking experienced Process Engineers to support purification of biologics, peptides, oligonucleotides, and bioconjugates. This position involves solving technical challenges with equipment design, developing and sustaining process knowledge, optimizing processes, and managing equipment capabilities.

Responsibilities

• Perform impact and risk assessments for the relevant equipment (chromatography skids/columns, TFF skids, etc.) and unit operations
• Learn the lab and plant design for the purification equipment including automation recipes and procedures.
• Ensure that people and their environment are safe and that company policies concerning safety are followed.
• Ensure processing equipment remains compliant with internal Quality System requirements, applicable engineering standards, and cGMP requirements.
• Assesses rig fit by receiving the technical data package for new processes and performing modeling, simulations and/or experimental work as required to ensure heat and mass transfer are acceptable when scaling to the plant.
• Active engagement and communication with: HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing.
• Author, review, or approve high-quality technical reports and regulatory submissions dealing with the work performed by the department. Ensure that records and technical notebooks are adequately maintained.
• Demonstrate engagement and employ a quality mindset in all endeavors by proactively identifying quality issues and communicating appropriately.
• Develop or review plans and timetables for project work.

Basic Requirements

• BS or MS in chemical engineering or related discipline and a minimum of 1-4 years of experience with a pharmaceutical, biotech, or CMO environment supporting the process engineering of drug substance active pharmaceutical ingredient (API) manufacturing or development.
• Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role.

Additional Preferences

• Deep technical interest and understanding in the field of Chemical Engineering
• Ability to work well in a team environment incorporating a variety of functional relationships and desire to be point of accountability
• Experience with any of the following software packages: DeltaV, OSI-PI, Dynochem, Aspen, and/or electronic lab notebooks
• Strong analytical and problem-solving skills
• Strong oral and written communication skills for a diverse audience, e.g., both operations staff and management.
• Ability to work on own initiative and as part of a Process Team consisting of a diverse group of management, production, science and engineering professionals
• Understanding of process control systems
• Creativity to identify improvement opportunities and the tenacity/initiative to see them implemented
• Guidance/mentoring of others through processes
• Flexibility to meet business needs

Other Information

• Initial location at Parkwood West, Indianapolis, IN.
• Permanent location at the new Lilly Medicine Foundry in Lebanon, Indiana.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form for further assistance.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $66,000 - $171,600.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees.