Senior or Principal Scientist: Cancer Biology & Immunology
Autonomous Therapeutics, Inc.
Cancer Biologist, Immunologist, or Cell Biologist We are looking for an exceptional cancer biologist, immunologist, or cell biologist to help advance first-in-class therapeutic candidates from discovery to IND. This is a growth-oriented position for an outstanding experimental biologist skilled in both cell-based and in vivo assays. You will join a growing team of 25 in-house scientists across our synthetic biology, chemistry, immunology, cell biology, and in vivo biology teams. You will report directly to the Head of Preclinical Biology and the President of R&D. About You You have a PhD in cancer biology, immunology, cell biology, virology, pharmacology or a related field. You have 5+ years of in vitro and in vivo biology expertise, PhD work included, and demonstrated expertise in ONE or more of the following: Cancer biology, metastasis, immune-cell biology, cell biology, or mechanisms of therapeutic response and resistance. Designing, optimizing, and analyzing cell-based assays to evaluate therapeutic candidates, including assays of viability, proliferation, cytotoxicity, apoptosis, or immune activation. Experience in flow cytometry, imaging, qPCR, ELISA, or high-throughput screening is highly preferred. Designing, executing, and analyzing in vivo studies to evaluate therapeutic candidates, including in tumor models, infectious disease models, or inflammatory disease models. Experience with immune / pharmacodynamic readouts, efficacy assays, toxicity readouts, tissue collection, biodistribution, or PK/PD is highly preferred. Additional experience in ONE or more of the following is strongly preferred: Experience with primary immune cells, PBMCs, organoids, co-culture systems, or other translational models. Experience with flow cytometry panel design, immune phenotyping, cytokine profiling, or functional immune assays. Deep experience with oncology efficacy models, infectious disease efficacy models, PK/PD studies, or biomarker-driven in vivo pharmacology. Experience evaluating and developing nucleic acid medicines, biologics, immunotherapies, cell therapies, antibodies, small molecules, or targeted cancer therapies. Education & Training: PhD in Cancer Biology, Immunology, Virology, Cell Biology, Pharmacology, or a related field is required. Experience: 5+ years of relevant in vitro and in vivo experimental biology experience, including PhD work. Publication record: A strong publication record is highly valued. Location: Rockville, MD (onsite) Autonomous Therapeutics, Inc.
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