Senior Manager, Clinical Operations - Cardiology

Senior Manager, Clinical Operations – Cardiology Location: Cambridge, Massachusetts and New York, New York. Hybrid work: in‑office collaboration two days per week in either New York City or Boston office. Where You’ll Drive Impact Study Activation Ownership & Execution Own the end‑to‑end site activations, managing timelines, dependencies, and risks across multiple concurrent sites and trials Help teams prioritize tasks and ensure milestones are met within defined SLAs Maintain activation plans, status tracking, and documentation, escalating risks and delays proactively Sponsor & CRO Partnership Serve as the primary operational partner to sponsors, CROs, and sites throughout the trial lifecycle Lead and support sponsor, CRO, and partner meetings by providing clinical operations expertise, actionable insights, and strategic recommendations Build strong relationships with key stakeholders and ensure alignment on study goals, performance metrics, and operational priorities Proactively communicate study risks, mitigation plans, and escalation strategies Facilitate educational sessions, webinars, and customer forums to strengthen engagement and share best practices Travel as needed to customer sites, investigator meetings, conferences, and sponsor engagements (up to 30%) Study Performance & Operational Excellence Monitor study performance metrics and own activation‑specific reporting, including time‑to‑activation, SLA performance, and root causes of delays Build and maintain dashboards that provide clear stakeholder visibility Use data to inform prioritization, process improvements, and resourcing decisions Identify operational gaps affecting site activation, enrollment, and execution, and collaborate cross‑functionally to address them Advocate for site needs and serve as a subject matter expert in clinical research operations Collaborate cross‑functionally to implement solutions that improve site performance and study outcomes Partner with sponsors and CROs to streamline processes and optimize site activation timelines Perform related duties as requested What You Bring to the Team Bachelor’s degree or equivalent combination of education and experience 8+ years of experience supporting Phase II–IV sponsor‑funded clinical trials Deep understanding of clinical trial operations, including study startup, feasibility, regulatory processes, protocol execution, and GCP requirements Experience working directly with sponsors, CROs, investigative sites, and cross‑functional stakeholders Demonstrated ability to manage multiple priorities, navigate ambiguity, and drive projects to successful completion Strong analytical, communication, and stakeholder management skills Comfort adopting and leveraging new technologies and operational tools Willingness to travel up to 30% Preferred Qualifications Experience in cardiology clinical research Prior project or program management experience 5+ years of experience as a Clinical Research Associate (CRA) or Clinical Research Coordinator (CRC), or 3+ years leading clinical operations teams Experience with CTMS platforms, with RealTime CTMS strongly preferred Experience working in a high‑growth or startup environment Experience presenting to sponsors, CRO leadership, and executive stakeholders Benefits That Support You Hybrid work environment with in‑office collaboration two days per week in either our NYC or Boston office Comprehensive medical, dental, and vision coverage, with up to 80% of premiums covered by Iterative Health Mental health and wellness support through Spring Health Health HSA or FSA options, and commuter FSA contributions supported by Iterative Health Unlimited PTO, 12 company holidays, and a company‑wide shutdown between Christmas and New Years 401(k) program with a company match of up to 3% (up to $3,000 annually) Weekly in‑office lunch benefit every Tuesday 100% company‑paid short‑term and long‑term disability coverage Annual wellness and professional development stipend to support your health and growth And more! EEO Statement As set forth in Iterative Health’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. #J-18808-Ljbffr Iterative Health