Senior Scientist I / II - Translational Experimental Cancer Biology (OTR)

Key Responsibilities Lead mechanism-of-action studies to interrogate therapeutic response and resistance in breast cancer models Design and execute in vitro assays to uncover intrinsic and acquired resistance pathways Engineer and optimize human cell line models for functional screening and mechanistic investigations Collaborate cross-functionally across discovery, data science, and early clinical development teams Analyze, interpret, and clearly communicate experimental data to drive translational insights Document experiments rigorously and maintain high-quality scientific records and reproducibility standards Stay current with emerging scientific literature and integrate new methodologies into research strategies Essential Requirements Doctor of Philosophy in biology, cancer biology, molecular biology, or related scientific discipline Strong expertise in cell biology and advanced molecular biology techniques Proven experience studying resistance to small molecule therapies using molecular approaches Deep understanding of hormone-driven cancer biology, including breast or prostate cancer Experience designing and executing in vitro assays to investigate cellular mechanisms Demonstrated ability to engineer and work with human cell line models Strong problem-solving skills and ability to interpret complex biological data Proven ability to collaborate effectively within multidisciplinary scientific teams Desirable Requirements Experience with data mining and computational analysis applied to biological datasets Familiarity with single-cell sequencing or spatial transcriptomics approaches #J-18808-Ljbffr Scorpion Therapeutics