Senior Director, Human Resources Business Partner, Global Commercial Strategy

Overview The Senior Director, Human Resources Business Partner (HRBP) provides strategic HR partnership to leaders across Global Commercial Strategy, U.S. Pricing & Access / Government Affairs, Global Pricing, and Health Economics & Outcomes Research (HEOR). Reporting to the Head of HR for Commercialization, this role focuses on talent strategy, organizational design, and supporting commercial transformation efforts. This role partners closely with the VP of Commercial Transformation to align people and organizational priorities with the broader Commercial Transformation agenda, and in support of the resources within the transformation office. Key Responsibilities HR Business Partnership – Serve as a strategic HR advisor to senior leaders across multiple Commercialization functions; provide guidance on organization design, talent management, and workforce planning; support leaders in aligning people strategies to business priorities. Commercial Transformation – Partner with Commercial Transformation leadership to support execution of transformation initiatives; translate business priorities into organizational and talent implications; support implementation of new operating models and ways of working. Talent Strategy – Support identification and assessment of critical roles across Commercialization; partner with Talent and business leaders on succession planning and development strategies; contribute to capability-building and commercial excellence initiatives. Organizational Effectiveness & Change – Support organizational design and change initiatives across supported functions; provide coaching and guidance to leaders during periods of change; use data and insights to inform talent and organization decisions. HR Delivery Model – Partner with a shared People Advisor who supports employee relations, performance management processes, and day‑to‑day HR needs; ensure alignment between strategic priorities and HR program execution. Qualifications 10–12+ years of HR experience, including HR Business Partner roles in complex, matrixed organizations. Experience supporting commercial, pricing, access, strategy, or value functions preferred. Experience in organizational design, talent management, and change initiatives. Strong business acumen and ability to influence senior stakeholders. Compensation Pay Range: $227,200 - $340,800. The role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Benefits Medical, dental, and vision benefits. Generous paid time off, including company shutdowns in the summer and winter. Educational assistance programs including student loan repayment. Commuting subsidy, matching charitable donations, 401(k) and additional benefits. Flexibility: Hybrid‑Eligible or On‑Site with up to two remote days or five days on‑site. Employment Type This hybrid‑eligible role allows the employee to work remotely up to two days per week or five days on‑site with ad hoc flexibility as per Vertex’s Flex policy. Equal Opportunity Employer Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. #J-18808-Ljbffr Vertex Pharmaceuticals Inc (US)