Sr. Research Scientist, Center Host Genetics

Sr. Research Scientist, Center Host Genetics (937675) Works under broad direction to plan, organize, direct, and participate in work of major research project in field of specialization for which incumbent is particularly qualified by virtue of extensive training and experience. The Zhao Zhang Lab is seeking a Senior Research Scientist to lead translational research on the molecular mechanisms of metabolic disease and therapeutic target discovery. This position will involve development and execution of molecular, cellular, and in vivo studies to support target validation, assay development, screening, and mechanistic investigation in metabolic disorders. The scientist will independently design and conduct experiments, analyze complex datasets, and help drive research strategy in a collaborative academic environment. The ideal candidate will bring strong expertise in metabolic disease research, signaling biology, molecular biology, and mouse models, with experience contributing to translational discovery programs. Qualifications The ideal candidate will have a Ph.D. with substantial postdoctoral or equivalent research experience in metabolism, endocrinology, cell signaling, or related biomedical fields. A strong background in molecular biology, mammalian cell culture, assay development, CRISPR-based genome editing, screening approaches, and mouse studies in metabolic disease is preferred. Experience in translational research and target validation is preferred; experience in GPCR biology is a plus. Education and Experience Required education: PhD with major coursework in field of assignment Master's Degree with major coursework in field of assignment Bachelor's Degree with major coursework in field of assignment Required experience: 6 years research experience in field of assignment; including at 1 year at the level of Research Scientist or its equivalent with a PhD 9 years research experience in field of assignment; including at least 2 years at level of Research Scientist or its equivalent with Master's degree 12 years of research experience in field of assignment; including at least 4 years at level of Research Scientist or its equivalent with Bachelor's degree Knowledge, Skills and Abilities Work requires exercise of considerable judgment. Work requires need to establish mutual agreement or understanding of elements involved. Work requires personal contact with representatives of outside private and governmental organizations to make periodic reports to, or to obtain their support, assistance, or cooperation in, matters affecting large-scale programs. Physical Demands/Working Conditions Extreme cold, extreme heat, hazards, laboratory setting. Security This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. Benefits UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include: PPO medical plan, available day one at no cost for full-time employee-only coverage Paid Time Off, available day one Retirement Programs through the Teacher Retirement System of Texas (TRS) Paid Parental Leave Benefit Wellness programs Tuition Reimbursement Public Service Loan Forgiveness (PSLF) Qualified Employer EEO Statement UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; gender, including sexual harassment; age; disability; citizenship; and veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression. #J-18808-Ljbffr The University of Texas Southwestern Medical Center