Head of Sales - Sigmatic Sciences (United States)

About Sapio Sciences

Sapio Sciences is on a mission to accelerate scientific drug discovery and high-throughput clinical and diagnostics for our clients and partners. The Sapio team consists of expert and highly collaborative scientists, software developers, and professionals passionate about providing a best-in-class lab informatics platform and industry-specific solutions.

Sapio is one of the few software providers to offer a truly unified and highly configurable lab informatics platform and a broad suite of purpose-built solutions. The Sapio platform makes it easy for scientists, laboratory, and bio/informatics professionals to streamline and manage their end-to-end laboratory operations, from instrument data integration to workflow and experiment setup to sample and materials management, data management, and scientific data analysis and reporting.

Working at Sapio

At Sapio, we’re not just building lab informatics solutions. We’re creating tools made for the scientist and motivated to make the world a better place. We understand that lab informatics is about more than managing data or connecting workflows. It’s about making life easier for the scientist and making scientific progress faster for everyone. Our platform delivers the levels of configurability, usability and insight that scientists have only ever dreamed of.

We’re a team of scientists, developers and innovators who question convention and stay focused on what matters most - advancing drug discovery science. We challenge the status quo and respond to the needs at the heart of science with powerful solutions that are simple to use, effortless to evolve and downright easy to love.

As part of the Sapio team, you’ll work in a collaborative and forward-thinking environment where your ideas are valued, your growth matters and your work makes a difference.

We’re proud to partner with leading labs around the world, from ambitious start-ups to global organisations, who trust Sapio to support discovery, development and diagnostics with industry-first science-aware solutions.

About the Role
As Head of Sales, you own the sales motion for Sigmatic Sciences end to end — carrying the revenue number and building the team, methodology, and pipeline that deliver it. This is a global mandate weighted toward the United States and European markets, spanning new business, expansion, and retention across our Strategic Account Managers and Scientific Liaisons.

You will define how Sigmatic sells: the account planning, engagement model, and playbooks that make growth repeatable and forecastable. You will lead from the front — coaching the team while personally driving the most complex, highest-value deals. Marketing, Product, and Customer Success are your closest partners, and you will work in lockstep with them to convert demand, shape the roadmap, and secure long-term customer value. Sales execution, and the number, are yours.

This is a pivotal hire. You will build the growth engine that scales Sigmatic globally, turning a genuinely
differentiated platform into commercial momentum in a market that is only beginning to grasp what lab-in-the- loop can do.

Working Location
This is a remote role based on the East Coast of the United States, with regular travel to meet your global team, key customers, and Sapio leadership. Our people are distributed worldwide, with physical offices in York, PA; Fort Lauderdale; and London.

About the Role
• Own the number. Carry and deliver Sigmatic's revenue targets across new business, expansion, and net revenue retention and take personal responsibility for the strategic accounts that anchor the annual plan.

• Define how Sigmatic sells. Establish the account-planning methodology, engagement cadences, and expansion playbooks that make growth predictable, with Scientific Liaisons deployed to lead business-value conversations at the core of the go-to-market model.

• Run a disciplined operating rhythm. Own forecasting, pipeline hygiene, CRM discipline, and a visible, relentlessly managed set of KPIs that underpin dependable performance.

• Own executive relationships. Serve as the senior point of partnership and escalation on your most important and most complex accounts.

• Partner with leadership. Work with the CCO and wider leadership to set targets, shape priorities, and report on the health of the sales portfolio.

• Collaborate across the go-to-market team. Work closely with Marketing, Product, and Customer Success — converting demand into pipeline, feeding customer and market intelligence into the roadmap, and aligning on retention and expansion — without owning those functions.

• Represent Sapio and Sigmatic. Show up with credibility at industry events, customer meetings, and executive briefings as a senior commercial leader.

• A track record of leading enterprise B2B SaaS sales and consistently meeting or beating revenue, net revenue retention, and expansion targets in complex, multi-stakeholder accounts.

• Experience building and scaling a distributed sales or presales team across multiple geographies and cultures.

• Fluency in a recognized enterprise sales methodology (e.g., MEDDIC, Challenger, Force Management), with strong command of executive-level engagement and multi-year commercial negotiation.

• The ability to build the playbooks, cadences, and account plans a scaling team runs on — and to lead from the front on the hardest deals.

• Enough command of agentic AI, lab-in-the-loop, and in-silico approaches to sell their value credibly to scientific and executive buyers in therapy design and development.

• Experience selling into life sciences, biopharma, or diagnostics strongly preferred; familiarity with lab informatics and an existing network in pharma or biotech are distinct advantages.

• Exceptional people leadership — you inspire, develop, and hold a distributed team accountable to a high bar


• Strong executive presence and the credibility to engage C-suite and senior stakeholders as a peer


• Commercial acumen across account planning, renewals, and expansion, with a data-driven approach to


• forecasting and performance


• Clear, persuasive communication that builds trust quickly, both internally and with customers


• A collaborative operator who influences without authority and thrives cross-functionally


• Comfortable in a fast-paced scale-up where you build structure as you grow


• Willing to travel regularly across the US and to Europe to support your team and key accounts

Our People

At Sapio Sciences, our people are at the heart of everything we do. Our lab informatics solutions are powered not just by technology, but by a shared commitment to our core values—what we proudly call The Sapio Seven, aka EMBRACE:

- E mbrace the future

- M ake a difference

- B e true partners

- R emember why we’re here

- A ct with empathy

- C ommit to transparency

- E xcel in quality

These values shape how we work, how we grow, and how we deliver impact for our clients every day.

Reasonable Adjustments

We are committed to ensuring an inclusive and accessible recruitment process. If you require any reasonable adjustments, at any stage across the application, interview & assessment processes then please let us know. We will work with you to support your needs in confidence.

Diversity, Equity & Inclusion

We do not discriminate based on race, colour, religion, sex, sexual orientation, gender identity, national origin, age, genetic information, disability, or any other status protected by law or regulation. We intend that all qualified applicants be given equal opportunity and that selection decisions are based on job-related factors. We are committed to creating a diverse and inclusive workplace and encourage applications from all qualified individuals.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.