Senior Scientist II Discovery Bioanalysis, PK Sciences

Role: Senior Scientist II (Lab-Based) – Cambridge, MA. Novartis does not offer relocation support; only apply if your location is accessible. About the Role Provide internal lab based bioanalytical support investigating the PK/TK properties of low molecular weight and novel modality compounds. Responsible for setting up the new LC-MS workflow by engaging with the key stakeholders. Provide mentorship and insights for junior associates to support advance method development for custom discovery PK and PKPD. Collaborate as a subject matter expert in bioanalysis with biotransformation, in vitro and in vivo colleagues, as well as chemists and biologists with project teams. Independently conceives and runs complex experiments/workflows that implement project strategy. Analyzes, writes reports and communicates own results in project meetings. Implement technologies such as LC-MS/MS, SFC-MS/MS or LC-HRMS for low molecular weight and novel modality compounds. Explore automation and software related solutions to increase workflow efficiency. Collaborate with our CRO partners for special case custom BA method transfers to the CRO. Utilize established networks and build new connections, including outside the own department. Comply with local and Novartis‑specific rules and regulations. Essential Requirements B.S. (6+ years) or M.S. (4+ years) or Ph.D. (1+ years) in bioanalytical lab science in biotech or pharma industry. Agility to independently perform high quality and fit‑for‑purpose bioanalysis within short timelines; emergent scientific leader with good values and behaviours. Hands‑on experience in custom method development, various sample preparation (SPE, LLE, IMC, etc.) and quantitative analytical methods for LC‑MS (low‑ and high‑resolution) required. Agility to adapt and shift priorities as per business needs. Practices efficient time management to work under tight timelines, focuses on deliverables, and effectively prioritises experimental designs. High motivation, curiosity and creativity with the ability to thrive in a matrixed work environment and communicate effectively within multidisciplinary teams. Good oral and written communication and presentation skills to communicate key results to internal teams. Desirable Requirements Experience with BA data analysis and reporting PK/TK data is highly preferred. Proven track record of establishing new lab workflows is preferred. The salary for this position is expected to range between $98,700 and $183,300 per year. The final salary offered is determined based on factors such as relevant skills and experience; upon joining Novartis, salary is reviewed periodically. Your compensation will include a performance‑based cash incentive and may be eligible for annual equity awards. US‑based employees receive a comprehensive benefits package that includes health, life, and disability benefits, a 401(k) with company contribution and match, and other benefits. Employees are also eligible for a generous time‑off package including vacation, personal days, holidays, and other leaves. EEO Statement The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. Accessibility & Reasonable Accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e‑mail to View email address on click.appcast.io or call View phone number on click.appcast.io and let us know the nature of your request and your contact information. Please include the job requisition number in your message. #J-18808-Ljbffr Novartis ACC