Director, Commercial Excellence, Rare Disease

Application deadline:
Location: Madison 07940, New Jersey, United States
Contract type: Permanent
Job ID: 4496


Role Description

Your Role

The Director, Commerical Excellence will act as an operational leader and trusted partner to the Vice President, Rare Disease, ensuring that business priorities are translated into effective plans, decision forums, performance management, and cross-functional execution. This role will drive the operating infrastructure and organizational coordination needed to deliver on Rare Disease business objectives.

The Director, Commerical Excellence, Rare Disease will also ensure leadership has integrated, actionable insight across the patient and commercial funnel, enabling timely decisions, strong execution, and effective collaboration across Commercial, Medical, Market Access, Patient Services, Finance, Legal, and Compliance.

Your Responsibilities
• Act as a trusted strategic partner to the VP, Rare Disease, helping shape priorities, convert strategy into executable plans, and ensure follow-through on key business decisions.
• Lead the operating rhythm of the Rare Disease business, including leadership team meetings, performance reviews, trimester business reviews, planning cycles, governance forums, and action tracking.
• Own business performance visibility by synthesizing inputs from Analytics, Sales Force Effectiveness, Finance, and other stakeholders into clear, decision-oriented insights on performance, risks, opportunities, and required actions.
• Create and maintain an integrated view of the patient and commercial funnel, aligning Field, Marketing, Patient Services, and leadership on the metrics, business drivers, and interventions that matter most.
• Partner with Sales Operations to support targeting, segmentation, call planning, and territory design, ensuring recommendations are commercially sound, practical, and field-ready.
• Partner with Sales Operations to support incentive compensation plan design, goal setting, payout governance, and ongoing evaluation so incentives reinforce desired rare disease behaviors and business priorities.
• Serve as business owner for CRM and core commercial systems, setting priorities, improving adoption, enhancing business processes, and ensuring alignment with compliance, operational, and user needs.
• Lead high-priority cross-functional initiatives, including launch readiness, patient finding capabilities, referral network development, and other strategic programs critical to business growth.
• Drive alignment and execution across Commercial, Medical, Market Access, Patient Services, Finance, Legal, Compliance, and other key partners by identifying barriers, resolving issues, and accelerating decisions.
• Elevate executive effectiveness by preparing high-quality leadership briefs, presentations, business updates, and strategic materials for U.S. and global stakeholders.
• Lead the development and coordination of high-quality content for key business meetings, including Business and Budget Reviews, Board of Directors presentations, Joint Steering Committee meetings, and other leadership forums.
• Establish clear governance, accountability, and communication processes to ensure key initiatives remain on track and leadership has transparency into progress, dependencies, and risks.
• Promote a culture of operational excellence, continuous improvement, data-driven decision-making, and cross-functional collaboration across the Rare Disease organization.
• Apply prior experience working across markets or with global partners to support strong alignment between regional execu-tion and broader organizational priorities.

Your Qualifications
• Bachelor's degree required; advanced degree preferred in business, life sciences, public health, or related field.
• Significant experience in biotechnology, pharmaceuticals, or rare disease, with substantial experience in commercial operations, business operations, strategy, sales operations, consulting, or related functions.
• Strong understanding of rare disease commercial models, including patient journey complexity, referral dynamics, patient finding, access considerations, and field force effectiveness.
• Strong business acumen with ability to connect strategy, operational execution, and financial outcomes.
• Demonstrated success supporting senior executives and leading cross-functional business initiatives in a matrix environment.
• Experience with commercial planning, business reviews, performance reporting, and executive-level decision sup-port.
• Experience partnering with Sales Force Effectiveness, Incentive Compensation, Analytics, and Finance.
• Experience with CRM and commercial systems, including prioritization, adoption, process optimization, and governance.
• Prior people leadership experience preferred; strong matrix leadership experience is essential.

The base salary range for this position is $200,000 to $290,000 per year. The base salary range represents the anticipated low and high of the LEO Pharma range for this position. Salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role. In addition, some positions may include eligibility to earn commissions/bonus based on company and / or individual performance.

Beyond the skin

Join LEO Pharma, a global leader in medical dermatology, as we go beyond the skin to make a lasting impact. Our innovative approach sets us apart. We are dedicated to leaving a legacy that positively impacts patients, colleagues, and our planet.


LEO Pharma Inc. is an Equal Opportunity/Affirmative Action Employer. At LEO Pharma, we believe that our different perspectives, backgrounds, and attitudes are what enable us to make the best decisions, foster an inclusive culture, and meet the needs of the market we operate in. Therefore, we encourage you to apply for the position if you are excited about the role - even if you don't meet every single requirement listed, you might be just the pioneer we are looking for. With this in mind, applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. We believe in flexibility in all aspects - also when it comes to supporting our employees' diverse needs, hence, we offer hybrid work opportunities whenever possible.

For certain positions, LEO Pharma might complete a background check conducted by a third party.

LEO Pharma Inc. seeks information for job applications from candidates in the U.S. through only the following channels:
• the LEO Pharma Inc. website and Halogen Talent Acquisition, powered by Jobvite
• via email to/from addresses using only the LEO Pharma domain of "@leo-pharma.com"
• screening and interaction by telephone and through the Microsoft Teams platform.
Please note:
• LEO Pharma does not use Google Hangouts, Zoom or any other platform for any recruitment-related activities.
• Disregard any solicitation or request for information related to job applications with LEO Pharma via any other means and/or using email addresses with any other domain.
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