Associate Director FP&A, Clinical Accounting & Data Analysis

Job Description Associate Director, FP&A - Clinical Accounting & Data Analysis About Vertex Pharmaceuticals Vertex is a global biotechnology leader transforming lives through groundbreaking science. We’ve revolutionized treatment for cystic fibrosis and are applying the same rigorous innovation to sickle cell disease, beta thalassemia, and other serious conditions. Our culture champions bold thinking, scientific excellence, and genuine impact—where your work directly improves patient lives. Join a team where exceptional talent meets purpose-driven innovation in an environment that values both professional growth and work-life integration. The Opportunity Lead the strategic evolution of our Clinical Center of Excellence (CCoE) as Associate Director, FP&A - Clinical Accounting & Data Analysis. This is a high-impact role at the intersection of finance, analytics, and clinical operations—where you’ll shape how Vertex plans, forecasts, and manages a multi-billion dollar clinical portfolio. You’ll architect the financial intelligence framework that guides critical investment decisions across our pipeline, leading a team of two talented professionals while partnering with senior leaders across Finance, Clinical Operations, and beyond. This role is ideal for a strategic finance leader who thrives on complexity, drives operational excellence, and sees data as a catalyst for transformational insight. Location Cambridge, MA (Hybrid or On-site) What You’ll Do Drive Strategic Financial Leadership Shape the financial narrative for Global Clinical Operations, translating complex clinical and financial data into executive-ready insights that drive portfolio decisions Build and refine KPIs that matter—metrics that predict outcomes, identify risks early, and unlock investment opportunities across our clinical pipeline Partner with senior leadership to scenario‑plan our clinical future: where to accelerate, where to optimize, and how to maximize strategic value Own the Analytical Engine Lead evolution of our clinical trial accrual and forecasting models—driving accuracy, automation, and scalability as our portfolio grows Generate predictive insights from integrated clinical and financial data: enrollment trends, cost drivers, timeline risks, and resource optimization opportunities Deliver variance analysis and forward‑looking scenarios that move beyond reporting to true decision support Orchestrate Cross‑Functional Excellence Influence without authority across Clinical Operations, Accounting, Reporting, and HR to align assumptions, drive accountability, and ensure financial discipline Serve as the trusted finance partner clinical leaders turn to for strategic guidance and operational problem‑solving Collaborate with our Reporting & Analytics CoE to pioneer AI and emerging technologies that transform how we work Ensure Financial Integrity & Controls Oversee monthly/quarterly close activities for clinical expenses with precision and efficiency Maintain bulletproof audit readiness through robust SOX controls, comprehensive documentation, and proactive risk management Champion GAAP compliance and governance excellence across all clinical accounting processes Build & Develop Your Team Coach and mentor two direct reports, fostering technical depth, strategic thinking, and business acumen Create a culture of continuous improvement where innovation, learning, and healthy challenge are celebrated Design roles and responsibilities that scale with business needs while accelerating career growth What You Bring Required Experience & Expertise 8+ years in FP&A, accounting, or finance business partnering with progressive responsibility Clinical finance expertise: Deep understanding of clinical trial lifecycles, cost structures, enrollment dynamics, and R&D financial management Technical accounting mastery: GAAP, clinical trial accruals, journal entries, reconciliations, month‑end/quarter‑end close, and SOX compliance Leadership experience: Proven track record developing talent, coaching high performers, and building team capabilities Influence & impact: Demonstrated ability to drive outcomes across functions through strategic partnership, clear communication, and credibility Technical Skills Advanced financial modeling (clinical accruals, forecasting, scenario planning) Variance analysis and KPI development Financial systems fluency (ERP, planning tools, reporting platforms) Advanced Excel proficiency Executive communication and presentation skills Education Bachelor’s degree in Finance, Accounting, Economics, or related field What Sets You Apart MBA, CPA, CFA, or advanced finance/accounting credential Biotech/pharma experience: Understanding of CRO relationships, clinical trial agreements, and regulatory milestones Systems expertise: SAP, Anaplan, Oracle, Hyperion, or similar enterprise planning platforms Analytics mindset: Experience with data visualization tools (Tableau, Power BI) and process automation Innovation orientation: Curiosity about AI, machine learning, and emerging technologies that can transform finance operations Strategic thinking: Ability to see around corners, anticipate challenges, and proactively solve problems before they arise Pay Range $156,000 - $234,000 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law. Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status Hybrid: work remotely up to two days per week On‑Site: work five days per week on‑site with ad hoc flexibility. Our Commitment to Inclusion Vertex is committed to equal employment opportunity and does not discriminate based on race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other legally protected status. We believe diverse perspectives make us stronger. We actively seek candidates from all backgrounds who share our passion for innovation and patient impact. Ready to Make Your Mark? Apply now to join a team where your financial acumen drives scientific breakthroughs and transforms patient lives. Questions? Connect with our Talent Acquisition team at View email address on click.appcast.io Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io #J-18808-Ljbffr Dormont Manufacturing Co