Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Global Commercial Head - Prostate Cancer

As a Global Commercial Head of Prostate Cancer, you'll play a pivotal role in channeling our scientific capabilities to further our agenda to bring our novel, first-in-class PARP1-selective inhibitor to patients across the globe. The role has leadership accountabilities that are critical to the delivery of AZ business objectives and portfolio value targets. Working with the Global Franchise Head, you will be a critical part of the Global Franchise Team and enable the cross-functional teams to successfully deliver commercial with this asset.

As a Global Commercial Head of Prostate Cancer will be responsible for developing and driving the overall commercialization plans across indications and tumor areas, by collaborating directly with Global Product Teams (GPTs) and leading the Integrated Business Teams (IBTs) which includes members from Insights, Medical Affairs, Market Access, Diagnostics, Regional / Country teams, and other OBU functions. The role will work closely with Global Franchise Head, Global Product Lead, Commercial Heads in key regions, to ensure teams work effectively together and with the broader business.

This position is based in our US headquarters for our Global Oncology Business Unit, in Gaithersburg, MD but could also be based on our UK headquarters in Cambridge, UK. This role, reporting into the Global Franchise Head, will be a core member of the Global Product Team and leads the planning, creation and implementation of global launch readiness and brand planning.

Typical Accountabilities:

  • Accountable for global commercialization strategy for asset across the full indication set - first launch in metastatic hormone-sensitive prostate cancer, followed by breast cancer and subsequent prostate indications.

    • Own competitive strategy and competitive response planning for asset in a competitive class.

    • Lead global market shaping in advance of first launch with a focus on external engagement, partnerships, evidence generation and patient-centric solutions that support patient identification, scientific narrative and value demonstration

    • Own the global launch readiness plan and milestone framework from pre-readout through first launch

    • Lead the Integrated Business Team, bringing together Insights, Medical Affairs, Market Access, Diagnostics, Corporate Affairs, Regional and Country teams to develop and implement one global brand strategy.

  • Accountable for future-proofed revenue forecasts, long-range plan inputs and business cases that are informed by robust customer insight, competitive intelligence and commercial judgement.

  • Represent the commercial perspective at the Global Product Team, to senior executives and to governance committees, ensuring commercialization priorities and competitive strategy are properly reflected in investment and development decisions.

  • Engage Regional and Country commercial leadership to secure alignment on strategy, prepare core markets for launch, and share learning across markets.

  • Collaborate closely with and provide direction to cross-functional partners (e.g. Insights, Access, Medical, Sales, Training, Corporate Affairs) for the development and implementation of both strategic and operational plans

  • Collaborate with Market Access and the extended team to deliver a sustainable global pricing and access strategy at a brand level and across indications,

  • Contribute to the broader Oncology Therapeutic Area strategy across GU and breast tumor areas

  • Lead the global team to build commercial capability at global and market level. Lead by example in innovation, cross-functional collaboration and enterprise mindset — removing barriers and simplifying ways of working to maximize value for patients and for AstraZeneca.

Essential Requirements:

  • Bachelor's Degree in relevant field

  • 10+ years’ experience in pharmaceutical development and commercialization

  • Must have successfully launched brands at a country level, as well as global strategic marketing experience

  • Proven strong pre-launch and launch excellence capability in a competitive setting

  • Demonstrated ability to partner with R&D and medical organizations to identify strategic development opportunities and shape development plans with associated value to the brand

  • Strong business acumen and working knowledge of forecasting, market research, insight generation, pricing and competitive intelligence to build effective commercial strategies and compelling business cases

  • Strong analytical, organisational and communication skills, written and verbal, including presenting to senior governance audiences.

  • Ability to thrive in ambiguity and lead without authority in a matrixed organization, with an entrepreneurial mindset and a track record of driving new opportunities and catalyzing others to build innovative solutions·

  • Proven cross-functional leadership, enterprise mindset, collaborative working and influencing skills, with demonstrated ability to inform, persuade and lead across markets and functions

  • Scientific curiosity coupled with ability to manage complex projects

  • High ethical standards and personal integrity ·

  • Effective stakeholder and relationship management, able to build trusted relationships at multiple levels inside and outside AstraZeneca.

Desirable:

  • MBA in relevant field

  • Sales/Customer-facing experience

  • Line management experience

  • Substantial Oncology experience

  • Experience in a precision-medicine or biomarker setting

Compensation and Benefits

AstraZeneca is committed to providing competitive, equitable and transparent compensation. The annual base pay for this position ranges from $231,988.80 - $347,983.20 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). 

Date Posted

04-Sep-2026

Closing Date

18-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Global Commercial Head - Prostate Cancer in Gaithersburg, MD vacancy
  •  ...bold ambition: to eliminate cancer as a cause of death....  ...of breakthrough science, commercial innovation, and global collaboration to bring life...  ...team as a Global Commercial Head, where you will play a pivotal...  ...and launch excellence. (Prostate, Breast Cancer, or PARP inhibitor... 
    Suggested
    Hourly pay
    Full time
    Temporary work

    AstraZeneca

    Gaithersburg, MD
    2 days ago
  • $267.91k - $401.87k

     ...antibody-drug conjugates (ADCs), and other emerging modalities.Reporting into the VP, Global Head, Hematology Franchise and sitting on the Leadership Team, as Head of Early Commercial & Innovation, Hematology, you will operate at the commercial-R&D interface to shape our... 
    Suggested
    Full time
    Temporary work
    Work at office
    Flexible hours
    3 days per week

    AstraZeneca

    Gaithersburg, MD
    6 days ago
  • AstraZeneca GmbH seeks a Strategy and Commercial Executive Director for Cell Therapy Strategy and Commercial (CTSC). You will shape end-to-end strategy for a therapeutic indication, lead global commercial initiatives, and align with clinical, data science, and market access... 
    Suggested

    AstraZeneca GmbH

    Gaithersburg, MD
    1 day ago
  • $168.1k - $268.7k

     ...As the Commercial Logistics Lead for US Distribution, you will play a pivotal role in...  ...alignment with BioNTech's mission to improve global health through innovative therapies. This...  ...addressing diseases with high medical needs like cancer and various infectious diseases.... 
    Suggested
    Worldwide

    Biontech

    Gaithersburg, MD
    a month ago
  • $267.91k - $401.87k

     ...therapy for people living with cancer, immune-mediatedand rare...  ...to late-stage development and commercialization. We are rapidly progressing a...  ...Cell Therapy. You will lead global commercial and strategic initiatives...  ...to Global Clinical Strategy Head (GCSH), Global Commercial and... 
    Suggested
    Temporary work
    Work at office
    Flexible hours
    3 days per week

    AstraZeneca GmbH

    Gaithersburg, MD
    22 hours ago
  • Summary: VIAVI (NASDAQ: VIAV) VIAVI is a global provider of network test, monitoring and assurance solutions for telecommunications,...  ...environment with Business Units groups, engineering , marketing, commercial teams and manufacturing locations across the globe. This role... 
    Full time
    Work at office
    Work from home
    Worldwide
    Home office

    Viavi

    Germantown, MD
    2 days ago
  • $180.2k - $231.85k

     ...Introduction Founded in 2010, Axtria is a leading global provider of cloud software and data analytics solutions tailored to...  ...We empower life sciences companies to reimagine their product commercialization journey, driving sales growth and enhancing patient healthcare... 
    Hourly pay
    Full time
    Worldwide

    Axtria, Inc.

    Gaithersburg, MD
    29 days ago
  • $143.1k - $238.5k

     ...Central PennsylvaniaGreater PhiladelphiaDelware, Maryland, Virginia,New JerseyContribute to the profitability and growth of Fulton's commercial banking by building, developing and managing new and existing client relationships with businesses with revenue of $25-100... 
    Full time
    Temporary work
    Work experience placement
    Local area
    Work visa
    Flexible hours

    Fulton Financial Corporation

    Gaithersburg, MD
    3 days ago
  • $114.1k - $190.1k

     ...enhance the experience of our employees and customers. Overview This is a full-time, hybrid or onsite C&I career opportunity in Commercial Banking supporting one of our following regions:Lancaster County, PennsylvaniaLehigh Valley/Berks County, PennsylvaniaCapital... 
    Full time
    Temporary work
    Work experience placement
    Local area
    Work visa
    Flexible hours

    Fulton Financial Corporation

    Gaithersburg, MD
    2 days ago
  • A leading diagnostics company is seeking an Events Manager to oversee the planning and coordination of tradeshows, conferences, and VIP events. The ideal candidate will manage the event lifecycle from contract review to post-event reports while ensuring budget and execution...
    Contract work

    Meso Scale Discovery

    Rockville, MD
    2 days ago
  •  ...Project ManagerI am currently partnering with a highly respected commercial construction firm that is looking to add an experienced Project Manager to its growing team. This organization has built an outstanding reputation for delivering high-quality projects, developing... 
    For contractors
    For subcontractor

    gpac

    Gaithersburg, MD
    3 days ago
  • $186.01k - $279.02k

     ...GenAI-powered field tools — and we ship products, not reports. Every capability we build must deliver measurable field adoption and commercial impact.   We are hiring a Director, DS&AI Products who will lead a multi-indication AI product portfolio end-to-end, serve as... 
    Hourly pay
    Temporary work
    Work at office
    Flexible hours
    Shift work
    3 days per week
    Gaithersburg, MD
    10 days ago
  • $80k - $95k

     ...Does this sound like you? Complex losses. High-stakes decisions. One calm, capable leader. Project Director, Large Loss & Commercial $80,000–$95,000 annually, based on experience, plus a bonus opportunity. When a major commercial property loss occurs, people... 
    For contractors
    For subcontractor
    Immediate start

    Paul Davis Restoration of Suburban Maryland/DC

    Gaithersburg, MD
    10 days ago
  • $75k - $108k

    Follow your passion. Advance your career . Make a lasting impact. It all starts here. Workforce Supervisor, Commercial Production Lab Gaithersburg, Maryland, United States Company Overview GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform... 
    Local area
    Remote work
    Home office
    Shift work

    GeneDx, Inc

    Gaithersburg, MD
    3 days ago
  • Insurance Office of America is seeking a Director/VP, Commercial Lines to act as a national SME in Commercial Property & Casualty, partnering with divisional leadership to standardize workflows, optimize operations, and drive performance across the organization. The role... 
    Remote job
    Work at office

    Insurance Office of America

    Germantown, MD
    3 days ago
  •  ...seeking a Scheduling and Planning Manager to develop and maintain project schedules, baselines, and related reports for industrial and commercial projects nationwide. You will coordinate data from Project Managers, Superintendents, and owners representatives to ensure... 

    Sky Mavis

    Rockville, MD
    3 days ago
  • Insurance Office of America in Germantown, MD is seeking a Commercial Insurance Account Manager with 2-5 years of commercial insurance experience and an active P&C license to join our Account Management career path. The role supports remote/hybrid work with a 50‑mile onsite... 
    Remote job
    Work at office

    Insurance Office of America

    Germantown, MD
    1 day ago
  • Supernus Pharmaceuticals seeks a Manager of Commercial Data Strategy to guide data-driven decisions in a fast-paced commercial setting. The role focuses on customer journeys, data governance, and data quality across the Commercial Data Warehouse (CDW) while coordinating... 

    Supernus Pharmaceuticals

    Rockville, MD
    4 days ago
  • $145k - $160k

     ...revenue for 2024, Clayco specializes in the "art and science of building," providing fast track, efficient solutions for industrial, commercial, institutional, and residential related building projects. The Role We Want You For The Scheduling and Planning Manager builds... 
    For contractors
    For subcontractor
    Flexible hours

    Sky Mavis

    Rockville, MD
    3 days ago
  • $72.3k - $120.5k

     ...Account Manager, Commercial Date: Jul 24, 2026 Location: DULLES, VA, US, 20166-9442 ROCKVILLE, MD, US, 20850-5253 Company: Grainger Businesses Work Location Type: Hybrid About Grainger W.W. Grainger, Inc. is a leading broad line distributor with operations... 
    Full time
    Local area
    Worldwide

    Grainger

    Rockville, MD
    2 days ago
  • $110k - $140k

    Supernus Pharmaceuticals is an award-winning biopharmaceutical company with more than 30 years of experience in developing and commercializing products that treat central nervous system (CNS) diseases. At Supernus, we develop innovative products that help treat neurological... 
    Visa sponsorship

    Supernus Pharmaceuticals Inc

    Rockville, MD
    3 days ago
  •  ...coverage analysis, and assist with claims. Applicants should have a P&C Insurance License and at least three years of experience in Commercial Lines. The ideal candidate is organized, customer-focused, and has strong communication skills. Join us in Germantown, MD to... 

    Maryland, Inc.

    Germantown, MD
    5 days ago
  • HUB International in Rockville, MD is hiring an Account Manager for Commercial Lines. The role involves analyzing accounts, maintaining client relationships, and preparing proposals. Candidates should possess a minimum of two years' experience in commercial lines insurance... 
    Flexible hours

    HUB International

    Rockville, MD
    3 days ago
  • $55k - $65k

     ...Job Description Job Description Harders & Bradford Insurance Agency is seeking an experienced Commercial Lines Account Manager to manage and service our growing book of commercial business. In this role, you will be the day-to-day service contact for commercial clients... 
    Hourly pay
    Afternoon shift

    Harders & Bradford Insurance Agency

    Rockville, MD
    1 day ago
  •  ...Description The Opportunity Kapsons is partnering with a Fortune 1000 industry leader and one of the largest providers of commercial landscaping services in the United States to hire an experienced Account Manager – Commercial Landscaping. This is a highly visible... 
    Contract work
    Work at office
    Flexible hours
    3 days per week

    Kapson LLC

    Gaithersburg, MD
    1 day ago
  •  ...as needed. Requirements Associates, BA/BS preferred. HS Diploma required. P&C Insurance License required. At least 3 years of Commercial Lines experience as an Account Manager Experience with commercial auto, property, general liability, umbrella, inland marine,... 
    Contract work
    Work at office

    Maryland, Inc.

    Germantown, MD
    5 days ago
  •  ...coordinating daily jobsite activities, assisting with crew direction, maintaining safety standards, and ensuring quality execution of commercial drywall work. This role serves as a development path toward becoming a Foreman. Work is primarily on active construction sites... 
    Full time
    Local area

    Kids for the Future

    Gaithersburg, MD
    1 day ago
  • Account Manager - Commercial Lines, Annapolis, MD Job Responsibilities Review and analyze commercial accounts for coverage, limits, etc., and make appropriate recommendations to clients. Acquire an understanding of clients’ insurance objectives and critically analyze... 
    Work at office
    Local area
    Flexible hours

    HUB International

    Rockville, MD
    3 days ago
  • $125k - $290k

     ...A national accounting and consulting firm in Bethesda seeks a Commercial Tax Manager or Senior Manager with extensive partnership experience. The successful candidate will provide federal tax compliance and planning services to large companies and work closely with leadership... 

    Weaver

    Bethesda, MD
    4 days ago
  •  ...surrounded by a team of professionals who care. If this is the type of work environment you are looking for and you have experience as a Commercial Construction Project Manager, look no further and apply today! We are growing and need to add to our Project Management Team.... 
    Full time
    For subcontractor
    Live in
    Work at office
    Local area

    Eichberg Construction

    Rockville, MD
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Global Commercial Head - Prostate Cancer. Be the first to apply!