US Medical Director - Immunology

At  AstraZeneca , we are committed to turning scientific innovation into life-changing medicines for patients. The  US Medical Director – Immunology plays a pivotal role in shaping and advancing the  US medical strategy for  IV/SC and its lifecycle management indications, including  systemic sclerosis (SSc) ,  cutaneous lupus erythematosus (CLE) ,  lupus nephritis (LN) , and  idiopathic inflammatory myopathies (IIM) .

Reporting to the  US Medical Head, Immunology , this role is a core member of the  US Medical Team Immunology and will help define the scientific narrative, evidence generation plans, launch readiness activities, and scientific communications strategy in the US. This is a highly visible, cross-functional leadership opportunity that will directly influence how scientific data is translated into meaningful medical impact for clinicians, patients, and the broader healthcare community.

Key Responsibilities

In this role, you will:

• Co-shape and execute US medical strategy for lifecycle management , ensuring alignment with broader business and medical priorities.
• Develop and communicate the US scientific narrative across indications, translating complex clinical and scientific data into clear, accurate, and compliant strategies and materials.
• Support launch readiness for lifecycle indications, including scientific platform development, congress planning, internal training, scientific response planning, and medical information preparedness.
• Partner on evidence generation strategy , including  real-world evidence (RWE) ,  health economics and outcomes research (HEOR) ,  externally sponsored research (ESRs) , publication planning, and congress activities.
• Contribute to external scientific engagement plans with key experts, institutions, professional societies, and other stakeholders in a compliant and strategic manner.
• Provide medical review and scientific input for publications, training materials, FAQs, and promotional and non-promotional content in collaboration with cross-functional teams.
• Deliver scientific and clinical training for  Field Medical teams and internal stakeholders to build readiness across lifecycle priorities.
• Collaborate closely with global teams to ensure US insights and needs are reflected in global medical and development plans.
• Ensure full compliance with  FDA ,  OPDP ,  PhRMA , and  AstraZeneca policies, standards, and ways of working.
• Champion innovative and AI-enabled ways of working to improve efficiency and enhance medical impact.

Must-Have Qualifications

To succeed in this role, you should bring:

• An  advanced degree such as  MS, MD, PhD, or PharmD .
• A minimum of 5 years of experience in  medical affairs ,  clinical development , and/or  lifecycle management within the pharmaceutical, biotechnology, or academic sectors.
• Strong expertise in  immunology ,  rheumatology ,  autoimmune disease , or a closely related therapeutic area.
• Solid understanding of the  US regulatory and compliance environment , including  FDA and  OPDP requirements.
• Experience contributing to  evidence generation ,  RWE/HEOR ,  publications ,  congress strategy , and  scientific communications .
• Demonstrated ability to work effectively in a  cross-functional matrix environment and align  US and global medical priorities .
• Excellent  scientific communication ,  presentation , and  stakeholder engagement skills.
• The ability to translate complex scientific information into  clear, compelling, accessible, and compliant messages for diverse audiences.
• Strong  judgment ,  collaborative leadership , and a commitment to  high ethical standards .
• Willingness and ability to  travel within the US and occasionally  internationally .

Desirable Qualifications

The following would be advantageous:

• Prior experience supporting  launch readiness for new indications or lifecycle expansion opportunities.
• Experience working across multiple stakeholder groups, including  Medical ,  Commercial ,  Clinical Development ,  Regulatory ,  Market Access/HEOR ,  Medical Information , and  Patient Safety .
• Familiarity with building or refining  scientific platforms and  medical response strategies .
• Experience engaging with  external experts ,  institutions , and  professional societies in a compliant scientific exchange setting.
• Interest in or experience with  innovative and AI-enabled approaches to improve medical affairs effectiveness and execution.

Why Join AstraZeneca?

This is an opportunity to make a meaningful impact in a role that sits at the intersection of  science, strategy, and patient care . You will work with talented cross-functional teams, help shape the future of  Saphnelo across important lifecycle indications, and contribute to scientific advancements that can improve outcomes for patients living with serious immunologic diseases.

If you are a scientifically strong, collaborative, and strategic medical leader who thrives in a dynamic environment, we encourage you to apply and bring your expertise to a team committed to changing patients’ lives through science.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.