Senior Staff, HR Business Partner - BioInsight (San Diego / Hybrid)

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life‑changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world‑changing projects, you will do more and become more than you ever thought possible.

Position Summary

At Illumina, our HR team is highly collaborative, creative, and passionate about advancing our mission through our people practices. We are seeking an experienced Senior Staff HR Business Partner to support several organizations within our BioInsight organization. In this high‑impact individualcontributor role, you will partner closely with senior business leaders to translate business priorities into organization and talent strategies that enable performance, innovation and growth. You will serve as a trusted advisor to leaders, bringing strong business acumen, organizational insight and pragmatic HR expertise to complex business and people challenges. The successful candidate will combine strategic thinking with strong execution, operate independently across a broad range of organizational, talent and workforce priorities, and bring curiosity and demonstrated experience leveraging AI and emerging technologies to enhance the impact and effectiveness of HR work.

*This is a full‑time role, Monday through Friday, with an expectation of 3‑4 in‑office days per week and additional on‑site presence as needed. The individual must reside in the greater San Diego area and be able to commute to our corporate offices.

Responsibilities

Partner with senior leaders to understand business strategy, organizational priorities and key capabilities, translating them into actionable organization, workforce and talent strategies. Serve as a trusted advisor and thought partner to leadership teams, bringing a strong point of view on organizational effectiveness, talent, leadership, culture and the workforce implications of business decisions. Provide consultation on organization design, organizational effectiveness, team effectiveness and change management, including organization structures, roles and responsibilities, spans and layers, operating models and ways of working. Support organizations as they evolve and scale, identifying the organizational capabilities, skills and workforce requirements needed to deliver current and future business priorities. Build strong leadership teams and talent pipelines through succession planning, talent reviews, development planning, leadership coaching and thoughtful internal and external talent decisions; lead core HR processes including performance management and compensation planning. Use workforce data, business metrics and qualitative insights to diagnose organizational challenges, identify trends and inform talent and workforce decisions. Leverage AI and emerging technologies to enhance the quality, speed and strategic impact of HRBP work, including workforce analysis, scenario modeling, talent insights and decision support. Identify opportunities to automate and redesign HR workflows using AI‑enabled tools and agents, while applying sound judgment, governance and data stewardship. Help leaders understand the workforce implications of AI and other emerging technologies, including how work, workflows, roles, skills and organizational capabilities may need to evolve, and translate those implications into practical workforce and talent actions.

Qualifications

Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 8 years and a Master’s degree; or a PhD with 5 years of experience; or equivalent experience. Demonstrated success partnering with senior leaders in complex, highly skilled organizations; experience supporting scientific, technical, software, data/AI, bioinformatics, clinical or life sciences organizations is preferred. Strong business acumen with demonstrated ability to translate business strategy into practical organization, workforce and talent solutions. Demonstrated experience in organization design and effectiveness, talent management, succession planning, leadership development and organizational change. Strong consulting, influencing and communication skills, including the ability to constructively challenge senior leaders and bring an independent point of view. Demonstrated ability to use workforce data, analytics and business information to generate insights and influence decisions. Demonstrated experience applying AI tools and capabilities in an HR/HRBP environment to improve analysis, decision support, productivity or HR processes; experience experimenting with automation, AI‑enabled workflows or agents is strongly valued.

Other Competencies & Requirements

• Business Acumen & Intellectual Curiosity - quickly learns the business, its strategy, operating model and key drivers of performance.
• Strategic & Systems Thinking - connects business, organization, talent, technology and workforce considerations and anticipates broader implications.
• Consultative Leadership & Influence - builds trusted relationships while maintaining the confidence and independence to challenge assumptions and offer a strong point of view.
• Organizational Problem Solving - breaks down ambiguous and complex organizational challenges and develops pragmatic, scalable solutions.
• Data & AI Fluency - effectively combines workforce data, business insights and AI‑enabled capabilities to improve analysis, decision‑making and HR effectiveness; demonstrates curiosity and willingness to experiment with new technologies and ways of working.
• Change Agility & Learning Orientation - operates effectively through ambiguity and change, continuously learns and helps leaders and organizations adapt to evolving business and technology environments.
• Execution & Collaboration - works independently, prioritizes effectively and drives outcomes while collaborating seamlessly across HR disciplines and the broader business.
• Flexible to work across multiple time zones as business demands.
• Ability to travel as required. Anticipated travel is <10% of the time.
• This is a hybrid role with an expectation of 3‑4 days in‑office per week and additional on‑site presence as needed.
• #LI-HYBRID

Employment & Compensation

The estimated base salary range for the Senior Staff, HR Business Partner – BioInsight (San Diego / Hybrid) role based in the United States of America is: $141,600 - $212,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

• Access to genomics sequencing
• Family planning
• Health/dental/vision
• Retirement benefits
• Paid time off

Company Culture & Inclusion

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics.

We are proud to confirm a zero‑net gap in pay, regardless of gender, ethnicity, or race.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Background Checks

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Accommodations

If you require accommodation to complete the application or interview process, please contact View email address on click.appcast.io. To learn more, visit:

Visa Sponsorship

This role is not eligible for visa sponsorship.

About Illumina

The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity. We are made up of dedicated professionals, all‑in on creating a better world – and we need every skill set on our path to making genomics useful for all. Learn more about life at Illumina.