Senior Medical Director - Late Stage

Revolution Medicines seeks a Senior Medical Director to lead clinical development of oncology molecules targeting RAS-addicted cancers. The role focuses on ensuring data integrity, regulatory compliance, and successful preparation of clinical datasets for global regulatory submissions.

Responsibilities

• Oversee data integrity and accuracy for ongoing and completed oncology studies
• Guide query resolution, outlier adjudication, and clinical plausibility during data cleaning
• Collaborate with clinical teams on protocol design alignment with regulatory requirements
• Partner with regulatory affairs, biostatistics, and medical writing on submission documentation
• Lead clinical data review meetings and escalate issues requiring resolution

Requirements

• M.D. or equivalent medical degree
• Oncology clinical development experience
• Expertise in clinical trial data review, cleaning, and validation
• Experience preparing regulatory submissions (NDA, BLA, MAA)
• Strong knowledge of FDA, EMA, and ICH regulatory standards
• Demonstrated leadership in cross-functional clinical teams