Regional Manager - Oncology, Upper Midwest

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

The Regional Manager - Oncology, Upper Midwest (Minneapolis) is a dynamic individual with direct clinical sales management experience in oncology to support our oncology portfolio of liquid biopsy products. You will build, develop, and lead a high impact team of Oncology Specialists who are responsible for driving sales volume for BillionToOne's Northstar Liquid Biopsy products and services, while cultivating relationships with oncologists and other members of the extended cancer care community in the region.

You will deliver clinical information to both external clients and internal teams. You will also have significant influence over how the test is communicated to oncologists and the cancer care community, and contribute to how the test evolves to better serve market needs.


The Regional Manager is a remote position based in the Upper Midwest region or a nearby state and reports to the SVP of Sales and Commercial Operations. You must reside in this Region.

Responsibilities:

• Develop a comprehensive, data-driven sales strategy and business plan to build and grow market development throughout the region
• Build and lead a team of talented, high performing Oncology Specialists in the execution of sales strategies and optimization of opportunities to increase profitability and market share
• Recruit, Hire, Train, Manage, and Develop staff
• Develop and enhance customized pitches to Oncologists and cancer care community
• Use data to analyze sales results, identify industry trends, and stay abreast of competition to increase sales volume and drive success within territory

Requirements:

• Minimum 4+ years of field sales management experience leading a team of sales reps at a molecular diagnostics / liquid biopsy company required , specifically selling directly to Oncologists throughout the geographical region, with an existing portfolio of convertible client relationships
• Strong experience hiring, developing, coaching, and motivating a team of sales reps to exceed ambitious sales goals
• Demonstrated successful sales track record (eg. multiple award winning - President's Club, Chairman's Club, Circle of Excellence or equivalent), solid negotiation and closing skills, strong data analysis skills, understanding of buyer/decision maker types, exhibit effective selling, listening, presentation skills, strong focus on pull through, and good follow through skills
• Excellent organizational and communication skills (written and verbal) with demonstrated ability to effectively present to both internal and external customers.
• Effective time management skills required with a demonstrated ability to assess and prioritize opportunities required
• Exceptionally bright, flexible, self-motivated and results-oriented with strong interpersonal and analytical skills and the ability to think strategically as well as execute tactically
• Must act with a sense of urgency, with a focus on closing business
• Ability to assess the needs of Oncologists and their office staff with a focus on consultative sales, coordination of logistics, and problem solving
• Strong desire to work in a startup environment and build out a new territory and team

Nice-to-Haves:

• Experience in a start-up environment
• Clinical laboratory experience

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)

At BillionToOne, we are proud to offer a combination of a (1) base pay (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).

For this position, we offer a total compensation of $380,716 per year (at plan), including a base salary range of $215,866 per year. Commission potential is uncapped and can be significant.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne's Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified , with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com