Senior Manager, Analytical Operations

About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Senior Manager, Analytical Operations, you will report to the Senior Director, Analytical Development and Quality Control. You will lead the execution of routine analytical testing while overseeing the day-to-day operations of the Analytical Operations laboratory. In this role, you will partner closely with Analytical Development, Process Development/MSAT, Research, and Site Operations to support laboratory buildout and expansion, ensure timely delivery of high-quality data, and drive operational excellence. You will also play a key role in building and developing a high-performing team. What you’ll do Collaborate with Analytical Development and Site Operations to support laboratory buildout, maintenance, and expansion, including budgeting for reagents, consumables, and capital equipment Oversee equipment installation, qualification, troubleshooting, and lifecycle management (calibration and maintenance) Plan, schedule, and execute routine analytical testing to meet turnaround time requirements for Process Development/MSAT and Research teams Ensure accurate and complete documentation of testing activities in electronic laboratory notebooks Develop and monitor operational metrics to identify inefficiencies and drive continuous improvement in laboratory workflows Implement semi-automated or automated solutions for assay performance monitoring and control trending Lead and develop team members through regular feedback, coaching, and performance management Influence cross-functional stakeholders and effectively prioritize multiple projects in a fast-paced environment Promote a culture of scientific rigor, accountability, and continuous improvement Contribute to hiring efforts and build a high-performing, collaborative team What we’re looking for Bachelor’s degree with 7+ years of relevant experience, or an equivalent combination of education and experience Experience in cell therapy or a related field Strong background in analytical testing, including flow cytometry and cell-based assays Experience using tools for assay performance monitoring and data trending Demonstrated experience managing direct reports and supporting career development Highly collaborative team player, with experience interfacing between Analytical Development, Process Development, and/or Research Working knowledge of regulatory requirements and quality standards (e.g. FDA, ICH, and USP/EP) What will separate you from the crowd Experience leading digital or laboratory automation initiatives Experience working in a regulated, quality-driven environment Hands-on experience supporting laboratory investigations and audits in a GMP setting Experience with pluripotent stem cells and differentiation What you should know Occasional off-hours or weekend work may be required There may be potential exposure to BSL2 biohazard materials Physical Demands: You may be required to perform the following physical activities: standing, walking, and sitting for extended periods of time; frequent use of the hands, fingers, wrist, and greater arm to handle small materials, tools, boxes, and trays; lifting and carrying objects up to 10 Ibs; occasional overhead reaches and lifts; occasional lifts and reaches below the knee; occasional pushing and pulling of materials and objects with moderate forces; occasional crouching/kneeling, twisting, and squatting movements. The base pay range for this position at commencement of employment is expected to be between $160,000 and $200,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience How we work together for patients Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution Get to know us At Sana, we believe that a workforce with varied backgrounds strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients. Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover a generous portion of the cost for employee health coverage, making high-quality care more accessible and affordable. We offer ample time-off (various paid time off benefits, such as holidays, vacation, sick time, and parental leave), short- and long-term disability, employer paid basic life insurance, additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually. For more details on our benefits, visit Sana’s Benefits Portal. We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, social class (including caste/caste identity), taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law. To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.