Grad Co-op - Protein Design for Target Discovery

Job Summary Grad Co-op – Protein Design for Target Discovery What You Will Do During this program, you will conduct state‑of‑the‑art research in protein design for target discovery. Identify and catalog genetic variants that result in gain or loss of post‑translational modifications (PTMs) on therapeutically relevant cell surface proteins. Apply computational and AI-based approaches to model the structural impact of PTM gain/loss on protein epitopes and therapeutic target accessibility. Design and optimize binders against disease‑relevant epitopes exposed by loss of PTM. Apply laboratory binder discovery and characterization workflows to validate lead binders. Design and execute laboratory experiments to characterize binder specificity, target engagement, and functional activity. Collaborate with computational and experimental scientists to communicate research findings. Qualifications 18 years or older. Graduated with a bachelor’s degree from an accredited college or university. Currently enrolled in an MBA, Master’s, PharmD, or PhD program and completed the first year before the internship starts. Not employed at the time the internship starts. Located in the United States for the duration of the co‑op. Preferred Qualifications Currently pursuing a PhD in Computational Biology, Bioengineering, Biochemistry, Computer Science, or a related field. Experience with programming in Python and/or R. Strong analytical, problem‑solving, and communication skills. Experience with protein engineering, structural biology, computational protein design, or antibody discovery. Familiarity with AI/ML approaches for protein modeling and binder design. Experience with molecular dynamics simulations or protein structure prediction tools. Experience in conducting biochemical experiments in a research laboratory. Prior research experience in computational and/or experimental biological sciences. Benefits The base pay range for this opportunity in the U.S. is $30–$40 per hour. Benefits include a competitive wage, a collaborative culture, networking opportunities, community volunteer projects, and support for professional growth. Sponsorship Candidates must be authorized to work in the U.S. for the duration of this program. Sponsorship for future full‑time employment is not guaranteed. Equal Opportunity Employer Amgen is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. #J-18808-Ljbffr Amgen Inc. (IR)