Senior Scientist I
$100k - $115kWuXi AppTec Group
Overview Job Summary: Responsible to plan/perform/guide metabolite profiling and identification related DMPK studies and prepare study reports. Responsibilities Identification of drug metabolites using liquid chromatography-tandem high-resolution accurate mass spectrometry, NMR, and other analytical methodologies. Elucidates metabolic pathways involving the identification and quantification of metabolites in biological matrices (e.g., blood, plasma, excreta) more independently using HPLC with radioactivity detection and/or LC-MS/MS. Designs, conducts, and guides in vivo and in vitro metabolism studies. Handles radio-labeled materials (e.g., 3H, 14C). Designs, plans and carries out the more complex research. Provides multiple approaches during the planning step. Trains, coaches, or mentors others on technical, personal development or business issues. Works on extremely complex problems in which analysis of situations or data requires an evaluation of intangible variables. Exercises independent judgment in developing methods, techniques and evaluation criteria for obtaining results. Functions as a study director, principal investigator, or project coordinator including serving as a primary contact for sponsors, responsibilities include planning and supervising more complex and exacting research studies. Supervises personnel. Ensures optimum personnel performance through leading by example, motivation, and performance recognition. Reviews other scientists’ calculations, records, and reports. Writes comprehensive reports, recommending application of findings, and presents clear and concise oral reports of processes and accomplishments. Complies with all safety rules, practice good housekeeping, and maintain safe workplace without supervision. Learns, enhances, and shares technical knowledge of pharmaceutical areas, DMPK, ADME, In Life, Metabolism, and Bioanalysis. Participates in writing and review of Standard Operating Procedures (SOPs) and suggest practical changes. Follows company’s safety policies, practices and procedures in order to maintain a safe work environment. Other duties as assigned. Qualifications Doctorate Degree with >3 years related experience; Master's degree with >10 or BS> 14 years related experience or work equivalent experience. Any similar combination of education and experience. Knowledge / Skills / Abilities: An expert in the use of advanced experimental methods, concepts and techniques relevant to scientific discipline and specific area of DMPK Emerging skills in novel experimental methods, concepts and techniques Demonstrates independent thought and scientific creativity Demonstrates technical success and proficiency in projects Utilizes expert knowledge of scientific principles and concepts Collaboratively researches and proposes methodologies for projects Acts independently to research and propose new research projects and methodologies and implement them Good time management skills in order to perform multiple projects within deadlines Expected to initiate external publications and presentations Effective oral and written communication and interpersonal skills Good time management skill in order to perform of multiple projects within deadlines Ability to work in a team environment Follow and adhere to nonGLP guidelines/SOPs consistent with WuXi AppTec requirement Physical Requirements: Must be able to work in an office environment with minimal noise conditions. Must be able to work in lab setting with exposure to biohazards / chemicals (common organic solvents) Must be able to wear appropriate PPE Must be able to work in environment with variable noise levels Ability to push/pull 10 lbs routinely/ often / occasionally Clarity of vision Anticipated salary range: $100,000 to $115,000 An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management. #J-18808-Ljbffr WuXi AppTec Group
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