Development Specialist

Development Specialist

IRI believes in commitment, integrity and strategic workforce solutions.

Integrated Resources, Inc., is led by a seasoned team with combined decades in the industry. We deliver strategic workforce solutions that help you manage your talent and business more efficiently and effectively. Since launching in 1996, IRI has attracted, assembled and retained key employees who are experts in their fields. This has helped us expand into new sectors and steadily grow.

We've stayed true to our focus of finding qualified and experienced professionals in our specialty areas. Our partner-employers know that they can rely on us to find the right match between their needs and the abilities of our top-tier candidates. By continually exceeding their expectations, we have built successful ongoing partnerships that help us stay true to our commitments of performance and integrity.

Our team works hard to deliver a tailored approach for each and every client, critical in matching the right employers with the right candidates. We forge partnerships that are meant for the long term and align skills and cultures. At IRI, we know that our success is directly tied to our clients' success.

Job Description

Job Title: Development Specialist

Location: Lexington, MA

Duration: 6 Months+ (Possible Ext.)

Job Summary:

This individual will contribute to purification process development. They will be responsible for performing laboratory and pilot scale column chromatography, tangential flow filtration and analytical assays to support protein purification process development. The individual applies basic knowledge form various technical areas, industry practices and standards. Provides quality and productive output that is consistently timely, reliable and reproducible. The candidate must be customer focused, results oriented, science driven and embrace values.

Responsibilities:

• Perform batch mode and column chromatography in support of purification process development – 35%
• Perform ultrafiltration and diafiltration in support of purification process development – 35%
• Analyze, summarize and document data – 20%
• Interact with analytical development and cell culture groups as well as development and engineering groups to ensure proper information exchange – 10%
• Report any unexpected observations and suggest possible explanations and resolutions.
• Present data in group forums; suggest conclusions and experimental plans based on purification fundamentals.
• Examine literature and provide summaries in support of interpretations for experimental outcomes.
• Report to supervisor in the purification group within BioProcess Development group.

Education & Experience Requirements:

• MS BS (0-2 years) (in Chemical/Biochemical Engineering or related discipline with relevant industry experience.

• Product and purification process development experience in the biotechnology/pharmaceutical industry with practical experience around scale-up, technology transfer and manufacturing support of large scale GMP operations is desired.

• Familiarity with the operation of large scale purification equipment for chromatographic and filtration unit operations is desired.

• Engineering degree preferred.

• Keeps current with literature and latest technology developments, particularly in the area of separations.

Qualifications

Skills:

• Experience and knowledge in protein purification process development, including TFF, ion-exchange, affinity, mixed mode and HIC column chromatography.

• Experience in protein analytical methods, including spectrophotometry, ELISA, HPLC, enzymatic assays, SDS-PAGE and Western Blot.

• Demonstrated capability of high quality work and keen attention to detail.

• Proficiency in Microsoft Word and Excel.

• Strong interpersonal and communication skills.

• Self-motivated and highly adaptable to rapidly changing priorities.

• Ability to work as a team player to achieve departmental and company goals under tight timeline requirements.