Average salary: $150,200 /yearly

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  •  ...A cutting-edge biotechnology company is seeking an Associate Principal Scientist to design and execute impactful research projects for biopharmaceutical partners. This role involves advanced computational analyses to enhance cancer precision medicine and requires expertise... 
    Principal

    Tempus

    Boston, NY
    7 hours ago
  •  ...treated? A biotech company pioneering cutting-edge drug delivery technologies for the central nervous system is hiring a Principal Scientist, In Vivo Pharmacology to lead IND-enabling studies and support the development of large-molecule therapeutics. This is... 
    Principal
    Part time

    HW3

    Los Angeles, CA
    9 days ago
  • A global healthcare leader is seeking a Senior Principal Scientist in South San Francisco to support drug discovery initiatives. The role requires planning and implementing experiments using in vitro assays and technologies, alongside a strong focus on generating high-quality... 
    Principal

    Eli Lilly and Company

    San Francisco, CA
    5 days ago
  • A leading biopharma company in Cambridge, MA is seeking a Senior Principal Scientist I to lead the development and validation of complex biomarker assays. This role requires extensive expertise in flow cytometry and assay design, along with proven leadership skills. The... 
    Principal

    BioSpace

    Cambridge, MA
    1 day ago
  • A leading global healthcare company is seeking a Sr. Principle Scientist to oversee Small Molecule manufacturing processes in Kinsale, Ireland. The role demands technical expertise, strong communication skills, and a solid understanding of regulatory expectations, aiming... 
    Principal

    Eli Lilly and Company

    Indiana, PA
    3 days ago
  • $132k - $193.6k

    A leading global healthcare firm is looking for a Scientist/Senior Principal Scientist in Indianapolis to support small molecule therapeutics. The role involves developing bioanalytical methods, conducting metabolite identification, and mentoring junior scientists. Candidates... 
    Principal

    Eli Lilly and Company

    Indianapolis, IN
    1 day ago
  • A global healthcare leader is seeking a Senior Principal Scientist in Alzey, Germany, to support technical transfer for injectable drug production. The ideal candidate will bring over five years of experience in the industry, strong project management skills, and knowledge... 
    Principal

    Eli Lilly and Company

    New Bremen, OH
    1 day ago
  • A leading biopharmaceutical company located in South San Francisco is looking for a Senior Scientist or Principal Scientist to join their Synthetic Molecule Analytical Chemistry group. The role requires a PhD in relevant sciences with industry experience and a proven track... 
    Principal
    Relocation package

    Genentech

    South San Francisco, CA
    2 days ago
  • $64.5k - $167.2k

    A leading pharmaceutical company in Indianapolis is seeking a Senior Principle Scientist for its External Manufacturing Organization. This role focuses on overseeing Small Molecule manufacturing processes, ensuring compliance with regulatory standards, and providing technical... 
    Principal

    Eli Lilly and Company

    Indianapolis, IN
    4 days ago
  • A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of... 
    Principal

    The University of Texas MD Anderson Cancer Center

    Boston, MA
    3 days ago
  • A leading biotechnology company in Bedford, Massachusetts, is seeking a (Senior) Principal Scientist in Cell Therapy. This hands-on role involves significant leadership in cell therapy discovery and development, advancing programs from early discovery to IND-enabling studies... 
    Principal

    PharmaEssentia U.S.A.

    Bedford, MA
    4 days ago
  •  ...Our Boston based biotechnology client is seeking a highly skilled Senior or Principal Scientist to lead the development, transfer, and validation of bioassay methods supporting innovative gene therapy programs. This role is ideal for a scientifically driven professional... 
    Principal
    Part time
    For contractors
    2 days per week
    3 days per week

    Stratacuity: Proven Scientific Placement

    Boston, MA
    2 days ago
  • A global biopharmaceutical company is looking for a Principal Scientist in Innovation Management. The role involves the development of upstream processes, oversight of biopharmaceutical production, and integration of digital tools in manufacturing. Candidates must have... 
    Principal

    Jobleads-US

    Fremont, CA
    1 day ago
  • A leading biotechnology company in South San Francisco is seeking a senior computational scientist to pioneer peptide therapeutic discovery. The role demands expertise in computational chemistry and machine learning to enhance our drug discovery pipelines. Responsibilities... 
    Principal
    Relocation package

    Genentech

    South San Francisco, CA
    3 days ago
  • A leading pharmaceutical company in Ridgefield, CT, is looking for a Senior Principal Scientist to drive in silico evidence generation for drug discovery. This pivotal role involves collaborating with interdisciplinary teams and leveraging advanced computational approaches... 
    Principal

    Boehringer Ingelheim GmbH

    Ridgefield, CT
    1 day ago
  • A pioneering biopharma company is seeking a Senior Principal Scientist I in Cambridge, MA to lead a team in developing complex immunophenotyping assays. Ideal candidates should possess a Ph.D. in a life science field and have 7+ years of relevant experience, particularly... 
    Principal

    Sanofi

    Cambridge, MA
    1 day ago
  • A leading biotechnology company in New York City is seeking experienced machine learning scientists for its AI for Drug Discovery group. The role involves developing innovative models to transform drug discovery processes using various data sources. Candidates should have... 
    Principal

    Genentech

    New York, NY
    5 days ago
  • A global healthcare provider is seeking a candidate for a scientific leadership role in RWE/Epidemiology studies. This position involves developing protocols and providing oversight on study execution while ensuring scientific rigor and quality. The ideal applicant will...
    Principal
    Remote work

    IQVIA

    Durham, NC
    7 hours ago
  •  ...Team This role work closely with a Senior Machine Learning Scientist and our Lead Machine Learning Infrastructure Engineer, alongside...  ...and collaboration with teams closest to the customer. As a Principal-level IC, you'll have real input into technical direction — not... 
    Principal

    Gather AI

    Pittsburgh, PA
    2 days ago
  • $65.25k - $169.4k

    A leading global healthcare company is seeking a candidate for bioconjugation process development in Indianapolis. The ideal applicant will have extensive experience in synthetic organic chemistry or biochemistry, focusing on the development of bioconjugates. Responsibilities...
    Principal

    Eli Lilly and Company

    Indianapolis, IN
    5 days ago
  • A leading biotechnology firm in Cambridge, Massachusetts, is seeking a Principal Scientist Liver to lead the liver portfolio. This role involves driving the discovery and development of novel RNA-based drug candidates for chronic liver diseases. Successful applicants will... 
    Principal

    ProQR Therapeutics N.V.

    Cambridge, MA
    2 days ago
  • A leading global company in Cambridge is seeking a Senior Scientist to advance lipid-based formulations for nucleic acid therapeutics. This role involves designing non-viral vectors, conducting in vitro experiments, and mentoring junior scientists. Ideal candidates have... 
    Principal
    Flexible hours

    Evonik

    Cambridge, MA
    4 days ago
  • A leading biotech company based in California seeks a Principal Scientist for their Immunogenicity Bioanalytical Sciences group. The role involves designing and validating assays for detecting drug antibodies, collaborating closely with R&D and regulatory teams. Ideal candidates... 
    Principal

    Amgen SA

    Thousand Oaks, CA
    1 day ago
  •  ...critical team member, you will operate and maintain mass spectrometry instruments, optimize analytical workflows, and collaborate with scientists across various research teams. Candidates should have a degree in Analytical Chemistry or a related field, alongside 3+ years of... 
    Principal

    Foghorn Therapeutics Inc.

    Watertown, MA
    1 day ago
  • $136.8k - $189.2k

     ...Job Title: Sr. Principal Scientist Job Number: 37086 Location: Boston, MA Job Description The role will be responsible for all operations involved with routine manufacturing and quality control testing of radiopharmaceuticals produced in Aktis’ GMP laboratory... 
    Principal

    The University of Texas MD Anderson Cancer Center

    Boston, MA
    3 days ago
  • A leading biopharmaceutical company in Ridgefield, CT is seeking a Principal Scientist to lead in-vitro antibody discovery efforts. The successful candidate will utilize advanced techniques like phage display and machine learning to identify therapeutic leads. The role... 
    Principal

    BioCT Innovation Commons

    Ridgefield, CT
    3 days ago
  • $145k - $175k

    A nonprofit research organization in Boston is seeking a Principal Scientist for Antigen Engineering & Production. The role involves managing high-throughput antigen production and leading complex projects while mentoring research associates. Candidates should have a Ph... 
    Principal

    Proteininnovation

    Boston, MA
    1 day ago
  • A biotechnology startup in Watertown, MA is seeking a talented Senior/Principal Scientist to lead the RNA Production Research Optimization team. This role involves the development of in-vitro transcription conditions for circular RNA therapeutics and requires extensive... 
    Principal

    Orna Therapeutics

    Watertown, MA
    1 day ago
  • A prominent biopharmaceutical firm in Cambridge is looking for a scientific leader to provide technical oversight in in vitro selection and cell-surface screening for viral and bacterial antigens. Candidates should have a PhD and at least 5 years of relevant industry experience...
    Principal

    Moderna Therapeutics

    Cambridge, MA
    3 days ago
  • A biotech startup is seeking a Senior/Principal Scientist to lead the development of next-gen RNA therapeutics. Responsibilities include optimizing IVT conditions and purification processes for circular RNA. Ideal candidates should possess a PhD with extensive experience... 
    Principal

    Orna Therapeutics, Inc.

    Oklahoma City, OK
    5 days ago