Average salary: $150,200 /yearly

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  •  ...Team This role work closely with a Senior Machine Learning Scientist and our Lead Machine Learning Infrastructure Engineer, alongside...  ...and collaboration with teams closest to the customer. As a Principal-level IC, you'll have real input into technical direction — not... 
    Principal

    Gather AI

    Pittsburgh, PA
    8 days ago
  • A global biopharmaceutical company is looking for a Principal Scientist in Innovation Management. The role involves the development of upstream processes, oversight of biopharmaceutical production, and integration of digital tools in manufacturing. Candidates must have... 
    Principal

    Jobleads-US

    Fremont, CA
    2 days ago
  •  ...technologies that will define Sunstar's future product platforms. Position Overview We are seeking a Senior, Lead, or Principal Scientist to serve as Team Lead of our New Technology Team, reporting directly to the Senior Manager of New Technology Development.... 
    Principal
    Worldwide
    Visa sponsorship

    Sunstar Engineering Americas Inc

    Springboro, OH
    15 days ago
  •  ...Principal Applied Scientist, Advertiser Growth, Amazon Sponsored Products & Brands Job ID: 3115279 | Amazon.com Services LLC The Sponsored Products and Brands team at Amazon Ads is re‑imagining the advertising landscape through industry‑leading generative AI technologies... 
    Principal

    Amazon

    San Francisco, CA
    2 days ago
  •  ...Job Description Job Description Principal Scientist / Study Director (Toxicology) Build Programs. Lead Science. Influence Outcomes. Why This Role Matters Here,  toxicology isn’t just about executing studies—it’s about shaping how therapies reach patients... 
    Principal
    Relocation

    RPM ReSearch

    Montevallo, AL
    a month ago
  • $147.3k - $245k

     ...of our company. Our product roadmap is exciting and ambitious. You will join a global team of curious, helpful, and independent scientists and engineers, united by a commitment to deliver cutting-edge, well-engineered Machine Learning systems. You will work closely with... 
    Principal
    Local area
    Remote work
    Home office

    Turnitin

    United States
    3 days ago
  •  ...Our pharmaceutical client is seeking a Principal Scientist who will be responsible for evaluating and interpreting analytical results, as well as developing, validating, and transferring analytical methods for APIs, intermediates, and raw materials. If you are someone... 
    Principal

    Germer International - Pharmaceutical Recruiting

    Waterloo, IA
    1 day ago
  • $220k - $260k

    Principal Scientist, Statistical Genetics & AI page is loaded## Principal Scientist, Statistical Genetics & AIlocations: Palo Alto (HQ)posted on: Posted Yesterdayjob requisition id: 2026011With the world’s largest database of more than eleven million genotyped customers... 
    Principal
    Local area

    23andMe

    Palo Alto, CA
    2 days ago
  • $269.4k - $412.6k

     ...we aim to make driving safer, smarter, and more connected, shaping the future of transportation on a global scale. Role As a Principal Technical Lead in Trajectory Generation within the Embodied AI organization, you will be a senior individual contributor driving... 
    Principal
    Relocation package
    Flexible hours

    General Motors

    Mountain View, CA
    1 day ago
  • $115k

     ...Principal Scientist, Innovation Management, Fremont CA Description As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides opportunity... 
    Principal
    Internship

    Jobleads-US

    Fremont, CA
    2 days ago
  • $140k - $250k

     ...Principal Scientist, Protein Sciences, Analytical Characterizations September 2025 Department: Technology Position Summary: TCG Labs-Soleil is seeking a highly experienced and driven Principal Scientist to lead our analytical efforts and join our multidisciplinary... 
    Principal
    Full time
    Temporary work
    Flexible hours

    Valid8 Financial, Inc.

    San Francisco, CA
    22 hours ago
  •  ...Principal Scientist, Chemical Development Overview: Position is directed toward optimization of existing chemical routes and development of alternate chemistry toward key synthetic intermediates and APIs. Carries out multistep chemical synthesis and product isolation... 
    Principal
    Local area

    Germer International - Pharmaceutical Recruiting

    Waterloo, IA
    22 hours ago
  •  ...lab to life while championing patients every step of the way. Learn more at We are searching for the best talent for a Principal Scientist, Analytical Comparability & Product Characterization – Advanced Therapies to be in Malvern, PA. Purpose: The... 
    Principal
    Full time
    Local area

    Johnson & Johnson

    Malvern, PA
    4 days ago
  • $158k - $197k

    Principal Scientist, In Vitro Pharmacology page is loaded## Principal Scientist, In Vitro Pharmacologyremote type: Onsitelocations: San Diego, CAtime type: Full timeposted on: Posted Yesterdayjob requisition id: JR000526Crinetics is a pharmaceutical company based in San... 
    Principal
    Local area

    Jobleads-US

    San Diego, CA
    2 days ago
  • $228.7k - $309.4k

     ...Job ID: 3161064 | Amazon Development Center U.S., Inc. AWS Agentic AI is looking for a Principal Applied Scientist who will partner with world‑class scientists and engineers to pioneer the next generation of AI‑driven development tools. Join the Amazon Kiro LLM‑Training... 
    Principal
    Work at office
    Local area
    Work from home
    Worldwide
    Flexible hours

    Amazon

    San Francisco, CA
    2 days ago
  •  ...translational science. They value rigorous science, collaboration, and innovation. What Our Client Needs Our client needs a Principal Scientist – Immunology to lead advanced immunology research, develop immune biology platforms, and translate scientific insights into... 
    Principal
    Full time

    PKR

    Franklin, TN
    2 days ago
  •  ...emphasis on human disease biology to drive meaningful therapeutic progress. What Our Client Needs Our client is seeking a Principal Scientist – Inflammation to lead disease-focused research efforts. This role centers on integrating human disease insights with... 
    Principal
    Full time

    PKR

    Franklin, TN
    2 days ago
  • $198.9k - $269k

     ...-powered growth through developing and evaluating the next generation search, recommendations, and agentic systems. As a Principal Applied Scientist on our team, you'll own the technical strategy and execution for our most ambitious AI-driven initiatives that directly accelerate... 
    Principal
    Temporary work
    Local area
    Flexible hours

    Amazon

    Seattle, WA
    3 days ago
  • $145k - $185k

     ...as Roche, GSK,and Zymeworks. For further information, pleasesee Job Description We are seeking a motivated Sr. or Principal Scientist to join the Histopathology Lab within the Target Validation team in San Jose, CA. The role involves independently designing,... 
    Principal

    Oxford BioTherapeutics

    San Jose, CA
    15 days ago
  • $137k - $235.75k

     ...and pioneering the path from lab to life while championing patients every step of the way. We are searching for a Senior Principal Scientist, Computational Multiomics, Precision Measures , to be in either Cambridge, MA; Spring House, PA; La Jolla, CA United States... 
    Principal
    Full time
    Temporary work
    Work at office
    Local area
    Remote work
    2 days per week

    Johnson & Johnson

    Spring House, PA
    4 days ago
  •  ...Principal Clinical Scientist What if your deep expertise in clinical trial design and regulatory science could directly influence how AI understands and evaluates clinical evidence for millions of patients worldwide? We're looking for a Principal Clinical Scientist... 
    Principal
    Ongoing contract
    Contract work
    Freelance
    Remote work
    Worldwide
    Flexible hours

    Alignerr

    San Antonio, TX
    3 days ago
  • $120k - $165k

     ...data internally and/or externally as needed. ~ Serve as the Principal Investigator responsible for interaction with the client from...  ...leadership for LC-MS as a Subject Matter Expert, and mentor junior scientists.  ~ Assist in improving policies, procedures, work... 
    Principal

    CRYSTAL PHARMATECH INC

    Pleasanton, CA
    25 days ago
  •  ...for GLP/GCLP sample testing and data reporting. Present and interpret data internally and/or externally as needed. Serve as the Principal Investigator responsible for interaction with the client from the study design to scheduling, conducting, reporting, and... 
    Principal

    CRYSTAL PHARMATECH INC

    Pleasanton, CA
    10 days ago
  •  ...by agencies will not be tolerated and may affect your ability to work with Adverum in the future. Adverum is looking for a Principal Scientist, Downstream Process Development to join the Process Development team at our Redwood City, CA office. The individual will be... 
    Principal
    Contract work
    Work at office

    Adverum Biotechnologies, Inc.

    Redwood City, CA
    6 days ago
  • $206.3k - $388k

     ...About the Role We are seeking a Principal Scientist (P60) to define and lead the data and semantic architecture that enables Adobe Firefly's next-generation unified foundation models -models that natively combine understanding, reasoning, and generation within a... 
    Principal
    Temporary work
    Local area
    Worldwide

    Adobe

    Seattle, WA
    4 days ago
  •  ...Job Description Job Description Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers) Location: Brisbane, CA (Onsite)   About BreezeBio BreezeBio is an early-stage biotech company building a next-generation delivery platform for genetic... 
    Principal

    BreezeBio

    South San Francisco, CA
    a month ago
  • $185k - $210k

     ...prominent technology and sustainability investors. About This Job: We are seeking an innovative, highly motivated, and experienced scientist to join our Bioprocess Development team. This role will be instrumental in developing, optimizing, and scaling upstream and/or... 
    Principal
    Full time

    UPSIDE Foods

    Emeryville, CA
    8 days ago
  •  ...is currently seeking a full-time Lead Architectural Historian/Principal Investigator to join our fast-paced team. In this role, you...  ...on the soil, groundwater, air, or the built environment. Our scientists, engineers, geologists, archaeologists, and historians provide... 
    Principal
    Full time
    Work experience placement
    Local area
    Night shift

    Metric Environmental

    Louisville, KY
    22 days ago
  •  ...Job Description Job Description As a Principal Bioinformatics Scientist at AccuScan Sciences, you will lead the development and improvement of statistical and algorithmic methods for NGS-based variant detection and minimal residual disease (MRD) calling. This role... 
    Principal

    AccuraGen

    Milpitas, CA
    29 days ago
  • $145k - $200k

     ...achieve our clients'​ project goals and objectives. The combined talent and experience of Terraphase's engineers, geologists, and scientists form the foundation for a comprehensive environmental management approach. Description Terraphase Engineering is... 
    Principal
    Work at office
    Local area
    Flexible hours

    Terraphase Engineering Inc

    Pleasanton, CA
    7 days ago