US HEVA Rare Asset/Indication Lead

Job title: US HEVA Rare Asset / Indication Lead Location: Morristown, NJ Job Description This role is accountable for leading U.S. health economics and outcomes research (HEOR) strategy and execution for the Rare Hemophilia portfolio—including ALTUVIIIO, QFITLIA, Eloctat & Alprolix, and Cablivi (aTTP). The incumbent serves as the primary U.S. HEVA point of contact for the portfolio and partners cross‑functionally to generate, translate, and disseminate high‑quality, decision‑relevant evidence that supports access in the United States. Main Responsibilities Strategic Business Impact Develop and implement U.S. payer‑specific HEVA strategy in close collaboration with cross‑functional team members, leading/implementing VEST team structure for the Rare Hemophilia portfolio. Drive measurable business impact through execution of HEVA tactics that directly support commercial objectives and market access goals compliantly and efficiently. Execute comprehensive U.S. HEVA tactics for the Rare Hemophilia portfolio, contributing to strategic planning and ensuring alignment with broader portfolio objectives. Partner with commercial teams to translate HEVA insights into actionable business strategies. Partner with access and medical team members to generate and disseminate actionable high‑impact evidence. Develop business‑relevant U.S. research agendas through cross‑functional input and alignment, ensuring evidence priorities are reflected in broader Sanofi planning documents. Internal Partnerships and Senior Management Engagement Build and maintain strong relationships with cross‑functional teams to ensure pricing and access decisions are aligned with the demonstrable value of the Rare Hemophilia portfolio. Align closely with the Global HEVA team to ensure U.S. insights inform global strategies and coordinate evidence generation, modeling, and evidence synthesis activities. Communicate complex health economics concepts and strategic recommendations to cross‑functional stakeholders with clarity and impact. Influence key business decisions through data‑driven insights and strategic HEVA recommendations. Ensure clinical development plans for Rare Hemophilia indications are designed to deliver true differentiation aligned to Sanofi's best‑in‑class or first‑in‑class ambition. Health Economics Research and Evidence Generation Oversee the design, execution, and publication of high‑quality health economics and outcomes research studies—including economic modeling, database analysis, observational research, systematic literature review, evidence synthesis, and AMCP dossier development—for the Rare Hemophilia portfolio. Contribute to the development of comprehensive real‑world evidence strategies that support product lifecycle management. Ensure scientific rigor and regulatory compliance across all HEVA tactics. Support the development of global launch strategies and provide strategic HEVA input into Integrated Evidence Generation Plans (IEGPs) for Rare Hemophilia indications to ensure alignment across clinical, real‑world evidence, and value demonstration objectives. Execute all HEVA tactics at the highest level of quality to compliantly further HEOR evidence dissemination, application, and proactive and/or promotional use with U.S. stakeholders (HCEI, PIE). Apply data‑driven decision‑making frameworks to prioritize evidence gaps and guide research investment decisions for the Rare Hemophilia portfolio, ensuring alignment between identified data gaps and strategic evidence generation priorities. Stakeholder Engagement and External Partnerships Represent Sanofi at major scientific conferences and industry forums, leading abstract development and presentation delivery for the Rare Hemophilia portfolio. Collaborate with external research partners and key opinion leaders to advance HEVA strategy and tactical plans in Rare Disease. Manage the U.S. HEVA budget for the Rare Hemophilia portfolio, overseeing vendor contracts, research investments, and resource allocation to ensure delivery of evidence generation priorities within budget constraints. Work with the team lead to engage with external evidence bodies (ICER, PDAB, IRA) and apply knowledge of their requirements to shape evidence generation and value demonstration strategies for Rare Disease. About You Education & Experience Advanced degree (Ph.D., M.D., M.Sc., M.P.H., or Pharm.D.) in health economics, epidemiology, public health, economics, pharmacy, or a related field (required). 3–5 years of experience in health economics, outcomes research, or a related field. Experience in rare disease therapeutic areas preferred, including understanding of disease areas, treatment paradigms, and market dynamics. Technical Skills Demonstrated experience in applying various HEOR methods and understanding the principles of evidence‑based medicine and clinical research; strong publication record is a plus. Knowledge of global HTA processes and guidelines. U.S. launch experience preferred; understanding of U.S. payer evidence requirements and value demonstration in a competitive market. Understanding of U.S. healthcare system and payer dynamics, with ability to translate evidence into strategic insights. Experience supporting market access and reimbursement through HEVA evidence (e.g., value tools, evidence summaries, AMCP dossier contributions). Working knowledge of U.S. evidence dissemination (HCEI/PIE, reactive/proactive, CFL). Experience in rare disease therapeutic areas preferred, including understanding of disease areas, treatment paradigms, and market dynamics. Experienced in statistical analysis methods relevant to HEOR, including ability to critically evaluate and apply quantitative evidence to support value demonstration and payer engagement. Foundational knowledge of AI and digital tools relevant to health economics, including familiarity with data analytics platforms and digital research tools; demonstrated willingness to develop proficiency with new AI‑enabled solutions to support HEOR research and evidence generation. Why Choose Us? Bring the miracles of science to life alongside a supportive, future‑focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high‑quality healthcare, prevention and wellness programs and at least 14 weeks’ gender‑neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affluent Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender, gender identity or expression, affectional or sexual orientation, disability, veteran or military status or liability for military status, domestic violence victim status, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in company employee benefit programs, and additional benefits information can be found here. #J-18808-Ljbffr Sanofi