Director, Project Management & Strategic Operations (Cystic Fibrosis)

Job Description General Summary

Vertex is seeking a talented strategic colleague to serve in a critical role supporting the Disease Strategy Team Program Office in the Office of the CEO. The Strategy & Operations Director will partner closely with a Disease Area Executive (DAE) to drive special initiatives to support a particular DST. We are seeking a candidate that has a strong track record in strategic roles, along with cross functional collaboration and effective communication skills to apply for this opportunity. Key Duties and Responsibilities

Partners with DAE to lead strategic projects and high-profile initiatives Act as a liaison between cross functional colleagues to ensure alignment and coordination on a wide variety of cross-functional initiatives; Attends selected meetings on behalf of DAE Develops dashboards or other tools for reporting of KPIs, monitors ROI of key initiatives and identifies focus areas to drive action that accelerates our plan Drives the development of high-impact executive presentations Leads after action reviews of critical projects; provide recommendations for improvement of processes and systems Knowledge and Skills

Outstanding communication of information and ideas (written, PowerPoint, verbal), to varied audiences including senior and executive leadership Analytical, able to glean insights from data using excel and other tools, and communicate in a compelling, visual way Strong collaboration skills, with an ability to influence multiple stakeholders; builds mutual trust, respect and cooperation among team members Proven project management skills, including scenario analysis, business acumen and the ability to manage multiple tasks and priorities; adapt to new projects rapidly and effectively Strategic thinker with a track record of driving results Self-motivated; acts independently and prioritizes appropriately; embraces unexpected changes or challenges and drives to improved solutions in a fast-paced environment Proven ability to work in and influence a cross-functional team promoting collaboration and high performing team behaviors with an unwavering focus on what is best for the patients we serve Consistently displays sound ethics, good judgment and demonstrates Vertex’s core values Strong biopharmaceutical drug discovery and development acumen across multiple disciplines Education and Experience

Bachelor's degree Advanced degree (MBA, PhD, or MD) or comparable experience preferred Typically 10+ years of progressive, relevant experience with demonstrated experience in strategy, project management, and organizing and directing multiple teams and departments in healthcare/biopharmaceuticals Pay Range

$185,400 - $278,200 Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation

Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: Hybrid: work remotely up to two days per week; On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.

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