Director, Commercial Operations
Karius
Own the strategy and architecture for sales operations, including CRM systems, sales automation, territory design, and performance analytics Build and lead a high-performing commercial operations team and establish its long-term operating model Establish and govern sales goals, metrics, and KPIs across individual, team, and organizational levels Own end-to-end sales forecasting, including pipeline analysis, forecast preparation, scenario modeling, and performance reporting Design and govern sales compensation structures and incentive programs with Finance and HR Own vendor strategy, selection, contract negotiation, and budget management for the commercial technology stack Lead change management for new sales tools, processes, and systems Identify and operationalize cross-sell and upsell opportunities within the existing customer base Own data integrity across CRM and commercial systems, including governance standards and escalation paths Build and oversee sales training and enablement programs Coordinate commercial initiatives across Sales, Marketing, and Finance Translate data into strategic insight and identify organizational performance improvements Partner with Finance to monitor targets, flag variances, recommend course corrections, and support planning cycles Own market intelligence and competitive analysis to inform go-to-market strategy Report to the Chief Commercial Officer Requirements Bachelor's degree in Business, Marketing, Operations, or a related field MBA preferred 10+ years of progressive commercial operations or sales operations experience with a Bachelor's degree, or 8+ years with a Master's degree At least 4+ years in a people management role Experience ideally within life sciences, healthcare, or diagnostics Experience architecting and scaling commercial systems and infrastructure, including CRM platforms, sales automation, territory design, and performance analytics Command of the full sales forecasting lifecycle, including pipeline analysis, forecast modeling, scenario planning, and performance reporting Experience designing, implementing, and governing sales compensation structures and incentive programs Experience with vendor strategy, selection, negotiation, and budget management for commercial technology Experience leading change management for tools, processes, and systems Strong commercial and analytical abilities, including turning complex data into actionable insights Experience building alignment across Sales, Marketing, and Finance leadership Deep fluency in CRM systems (Salesforce or equivalent), sales analytics platforms, and data governance standards Track record of delivering results under ambiguity Written, verbal, presentation, and executive communication skills, including presenting to senior leadership and board-level audiences Excellent organizational and project management skills Ability to influence and collaborate across teams Ability to thrive in a fast-paced, dynamic environment High level of professionalism, integrity, and commitment to achieving results Passion for supporting Commercial teams and driving operational success Meticulous attention to detail and ability to manage competing priorities Core Competencies Demonstrates expertise in sales operations strategy, architecture, and performance analytics, with a strong focus on CRM systems and commercial technology management. Proven ability to lead teams, drive change management, and translate data into actionable insights for organizational improvement. Highest-signal resume keywords Sales Operations Strategy CRM Systems Management Sales Forecasting Lifecycle Change Management Leadership Commercial Analytics Hard Skills Sales Automation Performance Analytics Sales Compensation Design Pipeline Analysis Forecast Modeling Data Governance Vendor Selection Budget Management Territory Design Scenario Planning Soft Skills Executive Communication Project Management Collaboration Influencing Skills Attention to Detail Certifications & Qualifications MBA Preferred Industry Keywords Life Sciences Healthcare Diagnostics Commercial Operations Tools & Technologies Salesforce Sales Analytics Platforms Commercial Technology Stack #J-18808-Ljbffr Karius
- Redwood City, CA (Hybrid) or Remote (USA)Commercial - Sales Operations /Full-time /RemoteAbout KariusKarius is a life science, venture-backed clinical... ...to make rapid treatment decisions.Position SummaryThe Director of Commercial Operations is a strategic and operational...SuggestedFull timeContract workTemporary workWork at officeLocal areaRemote workShift work
- ...Description The Sr. Director, Commercial Operations is a senior commercial leader and strategic partner to Sales Leadership, responsible for the systems, processes, analytics, and customer success capabilities that enable effective field execution and informed commercial...SuggestedWork at officeFlexible hours
- Insurance Office of America seeks a Director of Commercial Lines to lead national P&C operations and drive workflow standardization across the brokerage. The role partners with divisional leaders to optimize performance, support M&A integration, and deliver exceptional...SuggestedWork at officeRemote work
- Karius is seeking a strategic Director of Commercial Operations to own sales systems, processes, and analytics that drive revenue growth. You will partner with Sales, Marketing and Finance to optimize forecasting, pipeline analytics, and capitalization of cross-sell opportunities...SuggestedRemote job
$177k - $265k
...belonging, purpose, and a team that welcomes you—because when you feel valued, you’re empowered to do your best work.Job SummaryThe Director, Commercial Management is responsible for commercial management oversight across Equinix’s portfolio major expansion construction...SuggestedFull timeContract workFor contractorsWork at office$211k - $264k
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering... ...responsible for business and technical operations in support of PDM outsourcing... ...responsibilities, reporting into the Senior Director, Head, Supplier Management, Operations...Full timeLocal areaWorldwide- ...cutting edge food into their cafes. We are a restaurant company that operates in contract food service. That means you will have the freedom... ...exciting opportunities for our people! Job Summary The Director of Operations is responsible for the overall success of the...Hourly payContract workWork at officeLocal areaFlexible hours
- ...individuals and strengthens communities, Rafiki Coalition is the place to make a meaningful impact Job Description: The Director of Operations leads Rafiki Coalition's facilities and business operations, project execution, vendor and asset management, safety systems...Contract workFor contractorsAfternoon shift
$210k - $250k
...Senior Director of OperationsThis position is on-site. If you are planning to relocate to the Bay Area please let us know in your cover... ...relocation assistance for this positionAs Senior Director of Operations, you will lead our manufacturing and operations as they scale...Contract workRelocationRelocation package$244k - $305k
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering... ...is a unique opportunity for a Clinical Operations Professional who has innate leadership... ...within Clinical Development, the Sr Director Global Vendor Outsourcing will lead the...Full timeContract workLocal areaWorldwide$180k - $195k
...Galvanize Therapeutics Galvanize is a biomedical platform company operating at the convergence of engineering, biology, and healthcare... ...re looking for a hands‑on Senior FP&A Manager, Operations and Commercial Finance, to join our Finance team. You will own our Revenue and...Full timeTemporary workWork at officeLocal areaRelocation packageFlexible hours2 days per week$35 - $40 per hour
...The Role Team Esface is hiring a full-time Youth Basketball Operations & Sales Manager, a hybrid role that is equal parts program... ...community events, and building relationships with school athletic directors Connect the Dots Across Programs Know every Team Esface...Hourly payPermanent employmentFull timeSummer workLocal areaRemote workShift workNight shiftWeekend workAfternoon shift- ...Equinix, Inc. seeks a Director of Commercial Management to lead oversight of major expansion projects across our regional portfolio. You will drive down costs, assure financial controls, and manage contract risk while guiding the broader design and construction function...Contract work
$252k - $315k
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing...Full timeLocal areaRemote workWorldwide$210k - $250k
...your cover letter or at the top of your resume. We are unable to offer relocation assistance for this position* As Senior Director of Operations, you will lead our manufacturing and operations as they scale their innovative medical device solutions. This is a pivotal...RelocationRelocation package$255k - $315k
...information can be found at rezolutebio.com The Director / Senior Director, Pharmacovigilance Operations will play a critical leadership role in building... ...its lead product toward regulatory approval and commercial launch. This individual will be responsible for...Full timeFor contractorsLocal areaImmediate start- ...Revolution Medicines seeks a Director of Supplier Management to lead drug substance manufacturing operations and strategic sourcing initiatives. This role manages the... ...pharmaceutical materials across development and commercial stages. Responsibilities Manage...Contract work
- ...Natera seeks a Senior Director to oversee all laboratory operations, ensuring quality service and regulatory compliance across clinical and technical functions. The role manages personnel, infrastructure, and processes while driving operational improvements and new product...
- ...Revolution Medicines seeks a Director of GMP QA Operations to lead quality oversight for assigned clinical and commercial oncology products. The role manages GMP compliance across external manufacturing partners and suppliers, overseeing drug substance through packaged...
$240k - $360k
...because when you feel valued, you’re empowered to do your best work.Role SummaryReporting to the VP Procurement, Operations and Business Enablement, the Senior Director, Supply Chain Operations and Intelligence leads the business transformation agenda for Equinix’s supply...Full timeWork at office$205k - $256.2k
...precision medicine and genomics testing), to oversee the entire operations of our Extended-Hours Support (ExHS) team, to provide key data analytics services for our lab production operations. As the Director of Operations for ExHS at our Data Science Production...Immediate startWorldwideShift workWeekend workAfternoon shiftEarly shift$150k - $170k
...scraps every year, paving the way for our upcoming launch of Mill Commercial—the industry’s first end-to-end solution for managing,... ...in an environment where physical hardware meets high-stakes operational challenges? Have you executed complex new product introductions...For contractors- ...Vaxcyte seeks a Commercial Project Manager to support vaccine launch readiness by managing integrated schedules, critical paths, risk logs, and cross-functional coordination. The role will track milestones, maintain governance structures, and provide visibility into commercialization...
$211k - $264k
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines... ...expansion, and organizational growth. Provide strategic and operational leadership within Regulatory Operations, contributing to...Full timeLocal areaImmediate startWorldwide$186k - $233k
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering... ....The Opportunity:As an Associate Director, you will be responsible for the following... ...regulatory requirements.SME for Clinical Operations GCP guidance, best industry practices,...Full timeWork at officeLocal areaWorldwide- ...Revolution Medicines seeks a Senior Director of Regulatory Information Management to build and scale the company's regulatory systems... ...oversee implementation of the Veeva Vault RIM platform, and drive operational excellence across global regulatory functions....
- ...Revolution Medicines seeks a Senior Director of Clinical Operations to oversee global clinical vendor contracts, budgets, and outsourcing strategy. This role leads vendor selection, contract negotiations, and relationship management across CROs and clinical trial vendors...Contract work
- ...Revolution Medicines seeks a Director of Regulatory Operations to lead global submission execution across its oncology portfolio. The role involves strategic oversight of submission planning, dossier preparation, team leadership, and process optimization to support portfolio...
$171k - $247k
...process.Minimum qualifications:Bachelor's degree or equivalent practical experience.8 years of experience in a management consulting, operations, business strategy, marketing strategy, investment banking, venture capital or private equity role.5 years of experience working...$160k - $210k
...international logistics, customs compliance, and supply chain operations. This role is responsible for managing global logistics networks... ...processes for all international shipments; prepare and review commercial invoices, packing lists, certificates of origin, and export...Full timeWork visaFlexible hoursShift work
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