Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Investigator

Kinetic Clinical Research

Job Description

Job Description

About Kinetic Clinical Research

Kinetic Clinical Research (“KCR”) is a growing, multi-site clinical research organization dedicated to expanding access to high-quality clinical trials in diverse and underserved communities. As part of our expansion in San Bernardino , KCR is partnering closely with San Bernardino Family Medical Clinic to build a robust, community-based research program serving local patients.

We are seeking a CA licensed MD or DO to join KCR as a Principal Investigator (PI) at our San Bernardino site.

The Opportunity

This role is ideal for a physician who:

  • Is interested in clinical research without the administrative burden
  • Values community-focused care and patient access
  • Wants to collaborate with an established family medicine clinic
  • Is open to long-term growth , leadership, and potential profit-sharing opportunities

Role Overview

As a Principal Investigator, you will provide medical oversight and leadership for clinical trials conducted at the San Bernardino site, in collaboration with San Bernardino Family Medical Clinic and KCR’s experienced research operations team.

KCR provides the infrastructure, staffing, and regulatory support — allowing you to focus on patient care, oversight, and study quality.

Key Responsibilities

  • Serve as Principal Investigator on assigned clinical research studies
  • Provide medical oversight and ensure participant safety
  • Review and approve protocols, informed consent documents, and safety reports
  • Supervise Sub-Investigators and collaborate with CRCs and clinic staff
  • Participate in Sponsor/CRO meetings, feasibility reviews, and monitoring visits
  • Support patient recruitment and retention within the San Bernardino community
  • Maintain compliance with FDA regulations, ICH-GCP, IRB requirements, and KCR SOPs

Therapeutic Areas

Studies may include (depending on background and interest):

  • Primary care and chronic conditions
  • Metabolic and cardiovascular disease
  • Gastroenterology, dermatology, or other specialties
  • Vaccines and preventive medicine
  • Other Sponsor-driven therapeutic areas

What We Offer


  • Strong collaboration with San Bernardino Family Medical Clinic
  • Established patient access and community trust
  • Experienced CRC, regulatory, recruitment, and QA support
  • Flexible engagement models (part-time, per-diem, or study-based)
  • Competitive compensation (per study or hourly)
  • Minimal administrative burden

Growth & Long-Term Opportunity

KCR is investing long-term in San Bernardino. Physicians who demonstrate strong leadership, study performance, and alignment with our mission may have opportunities to:

  • Take on expanded investigator leadership roles
  • Participate in study selection and site growth
  • Progress toward profit-sharing or equity participation based on contribution and site performance (Partnership opportunities are not guaranteed but are a core part of KCR’s growth strategy.)

Qualifications

  • MD or DO with an active, unrestricted California medical license
  • Board-certified or board-eligible in Family Medicine, Internal Medicine, or relevant specialty
  • Prior clinical research experience preferred but not required
  • GCP-trained or willing to complete GCP training
  • Interest in research, collaboration, and community engagement

Why Physicians Choose KCR

  • Community-based research with real patient impact
  • Strong operational and regulatory support
  • Physician-friendly culture
  • We treat investigators as partners , not contractors
  • We invest in people, systems, and compliance
  • We support growth beyond a single study
  • We are building a respected, scalable research organization
Vacancy posted 7 days ago
Similar jobs that could be interesting for youBased on the Principal Investigator in San Bernardino, CA vacancy
  •  ...Job Posting Under the supervision of a Deputy Labor Commissioner Supervisor (Senior Deputy) or designee, conducts intake investigations and/or less complex assignments for settlement conferences or inspections. Coordinates intake workshops or clinics in order to ensure... 
    Suggested

    California State Jobs

    San Bernardino, CA
    4 days ago
  • $300k

     ...FDA-approved medication in Alzheimer’s Disease.   Irvine Clinical Research is hiring a Neurologist who will serve as a Principal Investigator. The physician will oversee Phase 1, 2, and 3 clinical trials of some of the most promising drugs under investigation in memory... 
    Principal
    Full time
    Weekend work

    Irvine Clinical Research

    Riverside, CA
    17 days ago
  • $200k

     ...Transplant/Cell Therapy - Peds BMT - Clinical Investigator Loma Linda University Health (Loma Linda University Cancer Center, Loma Linda University School of Medicine and Loma Linda University Faculty Medical Group), Division of Transplant and Cell Therapy (TCT)/Hematological... 
    Suggested
    Relocation package

    Loma Linda University Faculty Medical Group (LLUFMG)

    Loma Linda, CA
    4 days ago
  •  ...Representative exam: Under the supervision of a Deputy Labor Commissioner Supervisor (Senior Deputy) or designee, conducts intake investigations and/or less complex assignments for settlement conferences or inspections. Coordinates intake workshops or clinics in order to... 
    Suggested
    Work at office

    California Department of Industrial Relations

    San Bernardino, CA
    3 days ago
  • $200k

     ...Hematological Malignancies is looking to recruit for faculty positions at open rank (Assistant/Associate/Professor) as clinical investigators, including leadership opportunities to join our team. We are seeking energetic faculty clinical investigators who desire to develop... 
    Suggested
    Relocation package

    Loma Linda University Faculty Medical Group (LLUFMG)

    Loma Linda, CA
    4 days ago
  •  ...Education; ensures that the school environment is conducive to academic excellence, social development, and student well-being; the Principal will work collaboratively with staff, students, parents and the community to foster a positive, inclusive, and nurturing... 
    Principal

    Association of California School Administrators

    Rialto, CA
    1 day ago
  •  ...Special Investigator The Division of Occupational Safety and Health (DOSH), better known as Cal/OSHA, resides in the DIR. Cal/OSHA protects and improves the health and safety of working people in California and the safety of passengers riding on elevators, amusement... 
    Work at office
    Local area

    California State Jobs

    Riverside, CA
    2 days ago
  • $120k - $125k

     ...KORE1, a nationwide provider of staffing and recruiting solutions, has an immediate opening for a Principal Process Engineer in San Bernadino, CA As a Principal Process Engineer, you will have a specialized focus on designing, optimizing, and troubleshooting continuous... 
    Principal
    For contractors
    Local area
    Immediate start

    KORE1 Technologies

    San Bernardino, CA
    2 days ago
  • $110k

     ...The University of California - Riverside is looking for a Principal Grant Finance Administrator to manage financial and administrative aspects of grants and contracts. This role involves pre-award proposal preparation and post-award financial management, ensuring compliance... 
    Principal
    Remote work

    University of California , Riverside

    Riverside, CA
    3 days ago
  •  ...Welfare Fraud Investigator The County of Riverside's Department of Public Social Services (DPSS), Special Investigations Unit, is seeking to fill a position for the Welfare Fraud Investigator throughout the Western Region of Riverside County. This recruitment may be... 
    Work at office
    Local area
    Night shift
    Weekend work

    GovernmentJobs.com

    Riverside, CA
    2 days ago
  •  ...A federal law enforcement agency is seeking Criminal Investigators to conduct complex drug-related investigations. The role involves preparing comprehensive reports and testifying in court. Applicants must be U.S. citizens with specialized experience or relevant graduate... 
    Relocation

    Drug Enforcement Administration

    Riverside, CA
    1 day ago
  •  ...Specialist in Riverside, CA to be the primary contact for members with unauthorized account activity. You will conduct initial investigations, monitor accounts for suspicious patterns, and document findings to resolve discrepancies. You will use risk management systems... 

    Altura Credit Union

    Riverside, CA
    1 day ago
  • $22 - $28 per hour

     ...paid after successful completion of the 90‑day introductory period. Full details shared during the offer stage. About Us APEX Investigation® is a trusted leader in Insurance, Workers' Compensation, Liability, and Human Resource Investigations. For over 40 years, APEX... 
    Hourly pay
    Work at office
    Immediate start
    Relocation package
    Flexible hours
    Night shift

    Apexpi

    Riverside, CA
    14 hours ago
  • $70.3k - $85k

    Title IX Investigator Office of Equity, Title IX & Student Conduct - California - Redlands, CA 92374, USA. Position: Administrative, Exempt (12 months), Full‑time (40 hours). Salary Range: $70,304-$85,000. Posting Date: April 28, 2026. Application Deadline: Open Until... 
    Full time
    Work at office
    Immediate start

    Marin Campus

    Redlands, CA
    3 days ago
  • $22 - $28 per hour

    Apexpi is seeking a Surveillance Investigator in Riverside, California. This role involves conducting both stationary and mobile surveillance to gather critical intelligence, producing detailed reports, and showcasing investigative skills daily. The position offers competitive... 
    Hourly pay
    Flexible hours

    Apexpi

    Riverside, CA
    2 days ago
  • $100.88k - $212.16k

     ...Overview Step into a role where your contracts expertise drives business outcomes at scale. As a Senior Principal Contract Specialist, you will lead the strategy, negotiation, and execution of high impact agreements that support Esri's most complex and visible programs... 
    Principal
    Contract work
    Relocation
    Relocation package

    Esri

    Redlands, CA
    2 days ago
  • Overview The Principle Account Executive is a senior field sales role responsible for making sales and obtaining high‑value orders/contracts through complex, consultative selling. The primary duty of this position is direct selling to strategic and enterprise customers...
    Principal

    Konica Minolta Business Solutions

    Riverside, CA
    2 days ago
  • $150k - $220k

     ...Cannon Civil Senior Principal Engineer You'll come for a job…but you'll stay for an exciting career! Engineering and designing reliable, responsive solutions. Since 1976, CANNON has provided creative solutions to clients in the energy industry, water resources, public... 
    Principal
    Work at office

    Cannon

    Riverside, CA
    3 days ago
  •  ...Physician Investigator Opportunities – Multiple Locations Nationwide At Headlands Research, we are dedicated to enhancing clinical...  ...Physician Roles Look Like at Our Company Physicians may serve as Principal Investigator or Sub-Investigator on Phase II–IV clinical... 
    Full time
    Part time
    Local area

    Headlands Research

    Riverside, CA
    4 days ago
  • Summary THIS IS NOT AN OPEN JOB ANNOUNCEMENT** This is a public notice for Drug Enforcement Administration Criminal Investigator GL-1811-7/9/11 positions open to U.S. Citizens. A job announcement will be posted on USAJobs on April 20th, July 20th, and October 19th, 2... 
    Permanent employment
    Local area
    Relocation
    Trial period
    Weekend work

    Drug Enforcement Administration

    Riverside, CA
    4 days ago
  •  ...Take the next step in your career as our new Assistant Investigator Associate to adapt to shifting priorities and business needs, coordinate tasks to ensure deadlines are met, and maintain accurate records and documentation. Other duties include support the preparation... 
    Weekly pay
    Flexible hours
    Shift work

    TradeJobsWorkforce

    Riverside, CA
    1 day ago
  •  ...Principal Project Engineer / Project Manager Are you ready to take the next step in your civil engineering career with a firm that values leadership, mentorship, and meaningful work? We're partnering with a well-respected, multi-disciplinary firm that is seeking a Principal... 
    Principal

    Bright Sky Recruiting

    Riverside, CA
    3 days ago
  • $100.88k - $212.16k

     ...Overview Step into a role where your contracts expertise drives business outcomes at scale. As a Senior Principal Contract Specialist, you will lead the strategy, negotiation, and execution of high impact agreements that support Esri`s most complex and visible... 
    Principal
    Contract work
    Relocation
    Relocation package

    Esri

    Redlands, CA
    5 days ago
  • None
    Full time

    ABS Kids

    San Bernardino, CA
    1 day ago
  • Looking for a place to grow your career and make a difference? RICK is the place for you! As a Project Engineer/Manager in Riverside, CA you will have an opportunity to work with a multi-disciplinary team on meaningful, landmark projects in the Riverside, CA area. As a...
    Principal
    Work experience placement

    HireRight

    Riverside, CA
    2 days ago
  • $68k

     ..., and has experience making real-time decisions to mitigate risk and prevent losses. What You’ll Be Doing Monitor and investigate suspicious activity involving: Wire transfers ACH transactions Debit card fraud Check fraud Zelle and other... 

    MRISpokane

    Riverside, CA
    3 days ago
  •  ...is an equal opportunity employer. Declaration sur l'egalite des chances: Konica Minolta est un employeur souscrivant au principe de l'egalite d'acces a l'emploi et de l'action positive. Nous considerons tous les candidats qualifies pour un emploi sans distinction... 
    Principal
    For contractors
    Work at office

    Konica Minolta Business Solutions Ltd

    Riverside, CA
    3 days ago
  •  ...Fraud Analyst Location: Riverside, California (Onsite) Role Overview The Fraud Analyst is responsible for detecting, investigating, and preventing fraud across various payment services. This position involves monitoring transactions and analyzing data to identify... 
    Immediate start

    Apex Systems

    Riverside, CA
    4 days ago
  • $78.7k - $111.9k

    Principal Contracts & Grants Officer Location: University of California Riverside Job Number: 31642843 Full/Part Time: Full Time Schedule: 8AM - 5PM Salary: $78,700 - $111,900 annually Position Information The Principal Contracts and Grants Officer (PCGO) is responsible... 
    Principal
    Full time
    Part time
    Local area

    University of California-Riverside

    Riverside, CA
    5 days ago
  •  ...Bixal does not provide visa sponsorship. What Will You Do? As a Principal Program Engineer at Bixal, you will play a critical role in...  ...note that candidates selected may undergo a background investigation and, if applicable, meet eligibility requirements for suitability... 
    Principal
    Temporary work
    Remote work
    Work from home
    Weekend work

    GrabJobs

    Riverside, CA
    4 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Investigator. Be the first to apply!