Chief of Staff
$120k - $150kKnit Health
About Knit Health Knit Health is building a novel clinical foundation model to improve how healthcare is delivered. We combine expertise in AI with deep clinical knowledge to develop safe, trustworthy systems that improve care, expand access, and reduce waste. Knit is led by a founding team with roots at the University of California, Berkeley. The team has developed a novel AI architecture designed to reason like physicians. We are now using that foundation model, together with frontier clinical LLMs, to build a next-generation clinical intelligence platform for healthcare providers. We are venture backed and work with U.S.-based health systems and data providers. Why this role The Chief of Staff will work directly with the CEO and senior leadership on some of Knit Health's most important and least structured problems. This is a role for someone who combines exceptional analytical ability with initiative, curiosity, judgment, and a builder's mindset. You won't just help define what should happen; you'll roll up your sleeves, create momentum, and help turn ideas into something the company can act on. You'll operate across strategy, fundraising, product, science, operations, and partnerships. At times, that means helping the CEO sharpen an emerging idea, pressure-testing what it implies, or collaborating on what the company should do next. At others, it means turning that thinking into a concrete plan, building the analysis or materials required to support a decision, bringing the right people together, and making sure the work actually gets done. A great Chief of Staff creates structure without constraining creativity. You listen for the underlying idea, challenge assumptions, recognize second-order implications, and turn free-flowing thinking into clear decisions and executable actions. You will frequently encounter important problems before there is a defined project, owner, or solution, and you'll be expected to develop a point of view, propose a path forward, and start moving the work ahead without waiting to be asked. This is an early-stage company, and the role requires comfort with both high-level strategic thinking and hands-on execution. You may move from a sophisticated conversation about company strategy, fundraising, or investor positioning to an operational problem that simply needs someone capable to take ownership of it. You'll work closely with an accomplished, highly collaborative leadership team spanning healthcare, AI, research, product, and business. The expectation is that you can engage with them as a thoughtful partner while also helping the organization move faster.
What we're looking for
Salary Range Knit Health offers a competitive compensation package that includes base salary, equity, and opportunities for advancement. The starting salary range for the Chief of Staff is approximately $120,000 to $150,000 per year . Benefits Generous benefits for full-time employees include: medical, dental, and vision coverage with 100% of premiums paid for employees and dependents (full coverage for dental, vision, and our Gold medical plan; employees may choose to buy up to Platinum); coverage begins on the first day of employment. Additional benefits include a 401(k) plan and 24 days of PTO annually.
Final Notes Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice. Knit Health is an equal opportunity employer and is committed to a diverse workplace. People from diverse racial, ethnic and cultural backgrounds, women, LGBTQ+ individuals, and persons with disabilities are highly encouraged to apply.
What we're looking for
- 3+ years of exceptional performance in a highly analytical, high-expectation environment such as top-tier management consulting, venture capital or investing, strategy and operations at a high-growth company, or a substantive Chief of Staff role.
- Strong analytical and strategic thinking. You can take ambiguous, complex problems, break them down, develop a point of view, identify broader implications, and drive toward a clear recommendation or decision.
- High intellectual curiosity and strong business judgment. You engage deeply with new ideas, ask incisive questions, challenge assumptions constructively, and are comfortable forming an independent perspective.
- A builder/operator mindset and comfort with the pace of an early-stage startup. You can move quickly from strategy to execution, work directly with data, and build or lead the first version of dashboards, internal tools, or other lightweight systems. You do not need to be an engineer, but you should be tech-forward and effective working alongside technical teammates.
- A high degree of initiative and ownership. You identify what needs to happen, create structure where little exists, develop a proposal, and move work forward without waiting for detailed direction.
- Exceptional communication skills. You can simplify complex ideas, create clear executive-level materials, and communicate effectively with people across different disciplines and levels of seniority.
- Strong interpersonal instincts and judgment. You can build trust quickly, work effectively with senior leaders, handle sensitive information with discretion, and collaborate across the company.
- Experience in health technology, AI, or another technically complex environment.
- Experience working closely with founders or senior executives, particularly in an early-stage or high-growth company.
- A background in economics, finance, or another quantitatively rigorous discipline; an MBA or other advanced degree is also welcome.
- Experience in venture capital, investing, finance, fundraising, or other investor-facing strategic work.
Salary Range Knit Health offers a competitive compensation package that includes base salary, equity, and opportunities for advancement. The starting salary range for the Chief of Staff is approximately $120,000 to $150,000 per year . Benefits Generous benefits for full-time employees include: medical, dental, and vision coverage with 100% of premiums paid for employees and dependents (full coverage for dental, vision, and our Gold medical plan; employees may choose to buy up to Platinum); coverage begins on the first day of employment. Additional benefits include a 401(k) plan and 24 days of PTO annually.
Final Notes Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice. Knit Health is an equal opportunity employer and is committed to a diverse workplace. People from diverse racial, ethnic and cultural backgrounds, women, LGBTQ+ individuals, and persons with disabilities are highly encouraged to apply.
Vacancy posted 3 days ago
Similar jobs that could be interesting for youBased on the Chief of Staff in San Francisco, CA vacancy
$150k - $200k
...Chief of Staff to the CEO As Chief of Staff to the CEO, you will sit at the center of how this company operates and makes decisions. You will own the operating cadence, drive cross-functional initiatives from problem definition to resolution, and handle the work that...Suggested- ...running and grown a high-caliber team turning the art of sales into a scalable science. About the Role We're looking for a Chief of Staff who will operate as a true extension of the CEO. This is a rare opportunity to work directly alongside the CEO and gain an...Suggested
$150.36k
...Summary As a Chief of Staff, provides advice and assistance in the planning, resourcing, leadership, coordination and direction of national Public Building Service (PBS) initiatives within a Business Line. Location of position: GSA, PBS - One position in each...SuggestedFull timePart timeWork experience placementWork at officeRelocationFlexible hours- ...Chief Of Staff We are looking for a Chief Of Staff to join our team in San Francisco. In this role, you will work directly with the CEO on initiatives across product, marketing, and operations. This is a part-time role, with the potential to transition into a full...SuggestedFull timePart time
$150k - $170k
...Chief Of Staff Workstream is a mission-driven company building the all-in-one HR, payroll, and hiring platform for managing the hourly workforce. There are 2.7 billion hourly workers, making up 80% of the global workforce, but this market has been heavily underserved...SuggestedHourly payWork at officeLocal areaRelocationFlexible hours- ...runs the real economy. Learn more about our vision in our manifesto. Role Overview: Our leadership team is looking for a Chief of Staff to act as a force multiplier who will allow them to carry out special projects and execute on our plan to become a generational...WorldwideShift work
- ...Chief of Staff San Francisco, California Full Time As Chief of Staff, you'll partner closely with the leadership team to drive strategy, execution, and team growth. This is a high-impact role where you'll align teams, optimize operations, and tackle critical...Full timeContract work
$150k - $250k
...raised $10M from leading venture investors. The five-person team works in person from San Francisco. This is the company's first Chief of Staff and a high-agency operating role with direct access to the founders. You will build context quickly, identify bottlenecks...Contract workRelocationRelocation package$10k
...Chief Of Staff Voice AI that resolves, not transfers. Most phone systems trap callers in menus and scripts. Vapi is the platform for deploying voice agents that know your business and can listen, adapt, and resolve in minutes. The numbers: 1 billion calls. 1 million...Flexible hoursShift work- ...Chief Of Staff This is a 5 day in office position in our downtown San Francisco office. About Us Preference Model is building automated ML research engineering. Existing frontier models are brittle when applied to real-world ML tasks. The present bottleneck is...Work at office
$125k - $175k
Pepr Ai Business Role We are building the AI Operator for growth to replace the traditional ad agency. We apply the quantitative rigor of high-frequency trading to digital ad spend, delivering 20–50% upside in spend efficiency for our customers. We already manage...Work at officeImmediate startRelocation package$153k - $183k
...of botany, neuroscience, AI, and climate, with our first commercial deployment on the horizon. The Role We're hiring a Chief of Staff to make the business side of the company run while our CEO does the thinking work only he can do. Our technical org, research,...Permanent employmentFull timeWork at officeLocal areaImmediate start- ...This is one of the most important roles within the company. As Chief of Staff, you will work closely with the CEO across many of the most important business functions - strategy, recruiting, operations, fundraising, culture, and more. We're willing to take 6 months to...RelocationVisa sponsorship
$10k
...company graduated from YCombinator (S25) and is scaling the team. Role Description: Halluminate is looking to hire a Chief of Staff to own strategic initiatives, set up operational systems, and drive horizontal priorities amongst the team. The responsibilities...Full timeTemporary workH1bWork at officeRelocationVisa sponsorship$150k - $175k
...Chief of Staff San Francisco, California About VSCO For years, we've helped photographers create their work. Now we're building what comes next. VSCO exists for photographers. Not as a side feature, not as an afterthought, but as the whole point. We build...Temporary workWork at officeLocal areaWorldwideMonday to FridayFlexible hours3 days per week- Nox Metals Job Opportunity Nox Metals is building modern American metals factories. You will: # Attract and hire top talent # Lead teams directly and set the pace for them # Write code # Build reporting and data layer # Solve problems # Focus on scale...
- ...Chief Of Staff This role is specifically targeting those in the San Francisco Bay area or nearby. Sacramento candidates also considered. This role is primarily remote, but will have some periodic on-site meetings. As the Chief of Staff (COS), you will be a force...Work experience placementRemote work
- ...Chief Of Staff Lydian is growing fast and sprinting towards the deployment of its first commercial project, which will convert CO2 into jet fuel at a larger scale than any other project in the world. As we work towards this milestone and grow the team across multiple...
- ...We're looking for a Chief of Staff to work shoulder to shoulder with our founder and help run the company. This is a strategic, full-stack role: you'll help set direction on the things that matter most and then roll up your sleeves to make them happen. It is not an assistant...
- ...As Chief of Staff at Emanate, you'll work directly with the founder to turn company priorities into execution across hiring, operations, GTM, finance, and team systems. You'll bring structure to fast-moving work-streams, drive follow-through on critical decisions, and...
$200k - $250k
...what Agentic AI can do in production - we ship real systems that run real business processes at scale. Role Overview As Chief of Staff to the CEO, you will be the strategic nerve center of the entire company - a true force-multiplier to Surojit Chatterjee (ex...Work at officeWorldwideRelocation- About Roger Roger is an AI platform that frees home health clinicians from paperwork so they can focus on what matters: delivering life-changing care to our most vulnerable elderly patients in the comfort of their homes. Backed by leading healthcare investors like...
$150k - $250k
...talent at innovative companies. Our team is 100% remote and we work with teams across the United States to help them hire. Chief of Staff Location: San Francisco, CA Company Stage of Funding: Early-Stage / Seed Office Type: On-site (5 days/week in San Francisco...Contract workWork at officeRemote workVisa sponsorship- ...Chief Of Staff We're automating compliance for banks and fintechs with AI agents that work like human analysts. We're looking for a Chief Of Staff to work directly with the CEO — someone who can operate across every function of the business, make the founder faster...Temporary workWork at officeRelocation packageShift work
- ...promote an efficient, economical and progressive organization. Assures development and establishment of adequate internal management control systems. Responsible for the effectiveness of management pertaining to the day-to-day administration of PBS staff programs....
$300k
...Chief of Staff San Francisco, CA About Goodfire Goodfire is a research company using interpretability to understand, learn from, and design AI systems. Our mission is to build the next generation of safe and powerful AI—not by scaling alone, but by understanding...Remote work- ...About the Role We're looking for a Chief of Staff to serve as a force multiplier for the CEO. This is a part-time contract role (at least 20 hours per week, with flexibility on scheduling) designed for someone who can move fluidly between strategy and execution....Full timeContract workPart timeBank staff
- ...Chief of Staff to the President About the Company Fast-growing provider of data-driven solutions for education institutions Industry Higher Education Type Privately Held Founded 2007 Employees 1001-5000 Categories Technology Consulting...
- ...Chief of Staff to the Chief Executive Officer (CEO) About the Company Innovative provider of cloud-based financial services for local & national governments Industry Computer Software Type Privately Held, VC-backed Founded 2012 Employees 501-...Contract workLocal area
- ...Chief of Staff to the Chief Executive Officer (CEO) About the Company Innovative digital financial services company Industry Internet Type Public Company Founded 2013 Employees 1001-5000 Categories E-Commerce & Marketplaces Financial...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Chief of Staff. Be the first to apply!

