Senior Principal Scientist, Agentic AI for Drug Discovery
Vertex Pharmaceuticals
Vertex Pharmaceuticals, a leading biotechnology company, seeks a Senior Principal Scientist to develop, test, and deploy AI-enabled methods for drug discovery across small molecules and proteins. The role is Boston-based with a hybrid work arrangement (3 days onsite weekly). The successful candidate will translate scientific requirements into autonomous AI workflows, collaborate across disciplines, and apply best practices in software development and DevOps to deliver production-grade AI systems. #J-18808-Ljbffr Vertex Pharmaceuticals
Vacancy posted 1 day ago
Similar jobs that could be interesting for youBased on the Senior Principal Scientist, Agentic AI for Drug Discovery in Boston, MA vacancy
- ...to accelerate the application of AI and agentic systems across drug discovery. Working at the intersection of Computational... ...scientifically rigorous AI co-scientists that enhance compound design,... ..., engineers, data scientists, and senior leaders across a matrixed...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week
- Job DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific computational methods and agentic AI systems for drug discovery. In this role, you will work across modalities with emphasis on...PrincipalSeniorFull timeSummer workRemote workFlexible hours2 days per week3 days per week
$119.7k - $222.3k
...artificial intelligence (AI) enabled strategies to... .... Experience in late discovery into clinical... ...therapeutic proteins, antibody drug-conjugates,... ...to be considered for Principal Scientist II. 4+ years of experience... ...to be considered for Senior Principal Scientist.Extensive...PrincipalSeniorFull time$119.7k - $222.3k
...artificial intelligence (AI) enabled strategies to... .... Experience in late discovery into clinical... ...therapeutic proteins, antibody drug-conjugates,... ...to be considered for Principal Scientist II. 4+ years of experience... ...to be considered for Senior Principal Scientist....PrincipalSeniorResearch
Cambridge, MAmore than 2 months ago$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence &... ...will help shape the future of drug discovery and development across... ...immunoscience meets bold, AI-powered research. In R&D, you... ...development Experience with agentic AI frameworks and their application...PrincipalSeniorFull time- Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects... ...design and omics pipelines with agentic workflows. The role demands... ...agent orchestration to accelerate discovery and translation within Flagship'...Principal
$137k - $215.27k
...a skilled cheminformatic scientist to join Takeda’s cheminformatics... ...learning to accelerate drug design. The candidate will... ...chemistry, DMPK, and AI/ML, defining a roadmap for... ...Accountabilities: Develop and apply agentic AI solutions for drug discovery, including autonomous or...SeniorMinimum wageLocal area$115k - $215k
...recommendations to project teams, senior leadership, and external... ...proteomics strategies that inform discovery, translational, and clinical-... ...making within fast-paced drug discovery environments.... ...organized, solutions-oriented scientist with the ability to manage multiple...PrincipalSenior- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...PrincipalSenior
$166.77k - $202.09k
...careers.bms.com/working-with-us. Principal Scientist, AI-Driven Oncology Target Discovery The Informatics and Predictive Sciences... ...—across the full lifecycle of drug discovery and development and... ...intersection of machine learning, agentic AI, and oncology discovery to drive...PrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$215k - $275k
...analytics, automation, and AI-native delivery to... ...learning, generative AI, agentic workflows, modern data... ...thought leadership.* Develop senior practitioners and... ..., architects, and data scientists. Set clear expectations... ...salary pay range for a Sr. Principal is $215,000 to $275,000...PrincipalSeniorTemporary workLocal area- ...and implement semantic/knowledge architecture enabling AI-driven reasoning across the drug discovery and development lifecycle. Mission Build the semantic... ...Experience building semantic foundations for AI/GraphRAG/agentic AI/scientific reasoning; LLM-based retrieval/reasoning...Principal
- We are seeking a Senior Principal Scientist to join the US Neuromuscular group based in Cambridge, MA and help drive translational biology drug discovery efforts with an emphasis on muscle biology . This is an opportunity for a scientific leader to advance portfolio projects...PrincipalSeniorLocal area
$138.6k - $257.4k
...Research is seeking an accomplished Imaging Scientist to join the Image Analysis team in... ...pathology, computational image analysis, AI/ML, and tissue-based oncology biomarkers... ...microenvironment biologyExperience supporting oncology drug discovery or early clinical development with image...PrincipalSeniorFull time- Scorpion Therapeutics in Cambridge, MA, seeks a senior Biomedical Informatics Architect to establish semantic foundations for AI-driven reasoning across discovery, preclinical, and clinical development. You will lead ontology governance, build RDF-based knowledge graphs...Principal
- ..., immunology, and biologics drug discovery and development. About RA... ...Therapeutics is seeking an experienced Principal Scientist to help establish and... ...to multidisciplinary teams, senior leadership, and external... ...computational sciences, supporting AI/ML-enabled protein...PrincipalSeniorFull timeLocal area
Synolo Therapeutics
Cambridge, MA28 days ago - ...Therapeutics in Cambridge, MA seeks a senior data product architect to design and evolve AI-ready scientific data products supporting drug discovery and development. You will connect... ...and governance. You will partner with scientists, knowledge architects, AI engineers,...Principal
$132k - $258.5k
Flagship Pioneering is seeking a motivated (Senior) Scientist in Machine Learning for its Cambridge, MA office. The successful candidate... ...will develop machine learning approaches to enhance drug discovery linking AI with quantum chemistry. This role requires a Ph.D. in a...SeniorWork at office$126k - $234k
...Summary#LI-Hybrid Internal Title: Principal Scientist II or Senior Principal... ...antibody-xRNA conjugates, from discovery through clinical translation... ...QSP, and PBPK/PD) that link drug pharmacology, tissue biodistribution... ...modeling workflows (e.g., agentic AI).• Proactively seek...PrincipalSeniorFull time- 1910 in Boston seeks an experienced computational chemist to lead drug discovery efforts. The ideal candidate will have a Ph.D. and extensive experience in quantum chemical methods and molecular dynamics simulations. This role involves collaboration across interdisciplinary...Senior
- 1910, based in Boston, is seeking a Computational Chemist to enhance drug discovery through innovative computational chemistry solutions. In this pivotal role, you will lead programs across various therapeutic modalities, ensuring collaboration with biology and medicinal...Senior
$146k - $236k
...harnessing recent advances in AI, machine learning, and data to... ...uncertainty behind Flagship’s drug development and investment decisions... ...teams, feeding field discoveries back as product requirements.... ...gaps associated with complex agentic work products. Responsibilities...PrincipalSenior$79k - $127.65k
...Translational Post Doctoral Researcher — Agentic AI for Neurodegeneration for a 2-year... ...reshaping how we build agentic AI systems for drug discovery and how we evaluate them. Traditional... ...reasoning. Evaluating whether an AI co‑scientist can synthesize across pathology,...Temporary workFixed term contractLocal areaRemote work$122.25k - $176.58k
Job Title: Principal Scientist, Systems and Disease BiologyLocation... ...and pioneer AI-powered workflows that... ...accelerate the path from discovery to patient impact. Ready... ...and deploying modern agentic analysis workflows to... ...decision points in the drug discovery process. Opportunities...PrincipalFull time$216k - $297k
...harnessing recent advances in AI, machine learning, and... ...machine learning scientists innovating on model architectures... ..., refinement, and agentic integration.Guide... ...action reasoning, target discovery, perturbation biology,... ...for-biology, AI-enabled drug discovery,...Principal$154.4k - $242.55k
...knowledge.Job DescriptionJoin Takeda as a The Senior/Principal Scientist, Analytical Cell Line Engineering and... .... Operating at the interface between Discovery, Global Biologics, Analytical... ...Openness to using digital, automation, and AI-enabled tools to improve data analysis...PrincipalSeniorMinimum wageTemporary workLocal areaShift work- ...Description The Immunology Discovery Therapeutic Area is seeking... ...accomplished and experienced Scientist to lead the Immune Cell Depletion... ...knowledge of preclinical drug discovery spanning target discovery... ...direct reports, peers, and senior leadership Establish and...PrincipalSeniorFull timeWork experience placementLocal area
- ...Planet Pharma GroupContact: ApplicationsEmail: ****@*****.*** are seeking a highly skilled Scientist to join our Biologics Discovery team and lead antibody discovery efforts. We are looking for someone who thinks carefully about target biology and...PrincipalSenior
$115k - $209k
...harnessing recent advances in AI, machine learning, and... ...We are seeking a Principal Scientist to join Pioneering... ...pipeline strategy as agentic capabilities: translating... ...lives in the heads of senior strategic and... ...commercial pipeline strategy, drug development, or therapeutic...SeniorCasual work- ...help us build a new generation of transpilation tools enabled by AI and modern verification techniques — bridging the gap between... ...ASTs, IR design, and the full compilation pipeline. Path B — AI Agentic Product You have shipped a production AI agentic system —...PrincipalSeniorFull timeRemote workRelocation packageFlexible hours
Code Metal
Boston, MA18 hours ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Principal Scientist, Agentic AI for Drug Discovery. Be the first to apply!
Related searches
- materials scientist Boston, MA
- scientist assay development Boston, MA
- entry level research scientist Boston, MA
- health scientist Boston, MA
- quality control scientist Boston, MA
- deep learning scientist Boston, MA
- application scientist Boston, MA
- scientist antibody discovery Boston, MA
- senior analytical scientist Boston, MA
- decision scientist Boston, MA