Program Manager

37261403 Program Manager – Capital Projects | Pharmaceutical Manufacturing | St. Joseph, MO | 24-Month Contract Location: St. Joseph, MO Duration: 24-Month Contract Schedule: 1st Shift | Minimum 45 Hours Per Week Work Arrangement: 100% Onsite Program Manager – Capital Projects Overview Sigma Inc. is seeking an experienced Program Manager to lead the design, construction, and commissioning of a large-scale animal vaccine manufacturing facility in St. Joseph, Missouri. This is an exciting opportunity for a seasoned capital projects professional with expertise in pharmaceutical manufacturing, biotechnology, life sciences, industrial construction, or large-scale facility expansions. The selected candidate will oversee all phases of project execution, from planning and design through construction, validation, commissioning, and operational readiness. The ideal candidate will possess a strong background managing capital projects exceeding $100 million, working with cross-functional stakeholders, engineering teams, EPC firms, contractors, and executive leadership. Key Responsibilities Capital Project Leadership Lead end-to-end project delivery for the design, construction, commissioning, and startup of a large-scale vaccine manufacturing facility. Manage project scope, schedule, budget, resources, and deliverables to ensure successful execution. Oversee project planning activities, governance processes, risk management strategies, and performance reporting. Ensure project milestones are achieved on time and within budget. Construction & Engineering Management Serve as the primary liaison between project stakeholders, architects, engineering firms, EPC contractors, construction teams, and equipment vendors. Coordinate design reviews, construction activities, equipment installation, commissioning, and facility startup activities. Monitor project progress and proactively resolve risks, delays, and resource constraints. Cross-Functional Leadership Lead collaboration across Engineering, Operations, Quality Assurance, Validation, Manufacturing, Regulatory Affairs, Procurement, and Supply Chain teams. Influence executive stakeholders and drive strategic decision-making throughout the project lifecycle. Provide leadership across multiple departments and functional teams, both directly and indirectly. Governance & Risk Management Establish project governance structures and reporting mechanisms. Maintain risk registers, mitigation plans, issue logs, and executive reporting dashboards. Ensure adherence to project controls, quality standards, and regulatory requirements. Required Qualifications Bachelor's Degree in Engineering, Construction Management, Mechanical Engineering, Chemical Engineering, Biomedical Engineering, or related technical discipline. Extensive experience managing large-scale capital projects, facility expansions, or new construction projects. Proven experience delivering projects exceeding $100 million in capital investment. Strong understanding of Front-End Loading (FEL) processes and capital project lifecycles. Experience managing engineering, construction, commissioning, and startup activities. Demonstrated success leading cross-functional project teams. Exceptional communication, stakeholder management, and leadership skills. Strong analytical, organizational, and problem-solving abilities. Ability to work effectively in fast-paced, high-pressure project environments. Preferred Qualifications Pharmaceutical manufacturing experience. Biotechnology or vaccine manufacturing facility experience. Life sciences, biologics, medical device, or regulated manufacturing industry experience. Experience working with EPC firms, contractors, and equipment suppliers. Familiarity with GMP-regulated manufacturing environments. Experience supporting facility commissioning, qualification, and validation activities. #J-18808-Ljbffr