Postdoctoral Research Associates, Bartesaghi Lab - Duke University

The Bartesaghi Lab ( invites applications for two postdoctoral associate positions to develop computational methods and data analysis pipelines at the intersection of machine learning and cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET), and sub-tomogram averaging, to address fundamental questions in the life sciences. Postdocs will join a collaborative, multidisciplinary team spanning Duke University (Computer Science; Electrical and Computer Engineering; Biochemistry; Neurobiology; and Cell Biology) and partner institutions, including the Van Andel Institute, Emory University, and the National Institute of Environmental Health Sciences (NIEHS). The Bartesaghi Lab has dedicated access to state-of-the-art research infrastructure, including cryo-EM and cryo-ET capabilities through the Pratt School of Engineering Shared Materials and Instrumentation Facility (SMIF), as well as high-performance CPU and GPU computing through Duke Research Computing. Responsibilities Successful candidates will work at the interface of machine learning and experimental biology. Responsibilities include developing methods that embed domain knowledge into machine-learning models and applying these approaches to structural biology and disease-related questions, with particular emphasis on Parkinson’s disease. A central goal is scalable analysis of large datasets from dynamic complexes acquired with modern, high-throughput cryo-EM and in-situ cellular tomography workflows. Qualifications Ideal candidates should hold a PhD in Computer Science, Electrical and Computer Engineering, Biochemistry, Cell Biology, or a closely related area. Candidates must have at least one first-author or substantial-contribution publication in a leading venue in applied machine learning and/or structural biology and have strong recommendation letters from established researchers in the field. Applications The application deadline is July 15th, 2026, but applications will be reviewed on a rolling basis as received. Positions are for 2-4 years depending on the candidate’s interests and experience. Start dates are flexible, aligned with PhD completion. Working at Duke Disclaimers Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, ethnicity, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation, or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. #J-18808-Ljbffr Duke University