Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Director, Discovery Sciences & Technologies

Gilead

This role leads discovery science and technology initiatives supporting drug development across multiple therapeutic areas and modalities. The Senior Director will oversee assay development and screening strategies while directing cross-functional teams in biochemistry, structural biology, and computational sciences to advance candidates toward clinical development.

Responsibilities

  • Lead high-performing team developing biochemical, biophysical, and cellular pharmacology assays
  • Establish assay and screening strategies for target discovery and lead optimization
  • Drive adoption of next-generation lead-generation technologies and screening methodologies
  • Provide scientific direction and data interpretation at project governance forums
  • Mentor and develop scientific leaders while fostering innovation and collaboration

Requirements

  • PhD in biochemistry, enzymology, biophysics, or related discipline
  • 15+ years drug discovery experience in industrial research environment
  • Deep expertise in protein-ligand interactions and biophysical technologies
  • Proven success developing biochemical and cellular assays for target validation
  • Track record advancing programs from high-throughput screening to development candidate
  • Experience leading and mentoring senior-level scientists in matrixed organizations
  • Strong written and verbal communication skills for scientific and non-scientific audiences
Vacancy posted 11 days ago
Similar jobs that could be interesting for youBased on the Senior Director, Discovery Sciences & Technologies in Foster, CA vacancy
  • $167.4k - $310.8k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...techniques. We are seeking a Senior or Principal Machine Learning... 
    Senior
    Full time
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $261.38k - $338.25k

     ...member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific...  ...the lives of patients for generations to come. As a Senior Director, Discovery Sciences & Technologies, at Gilead you will provide strategic and scientific... 
    Senior
    Full time
    For contractors
    Local area

    GILEAD Sciences

    Foster, CA
    4 days ago
  •  ...tropism, and immune activation Establish LNP characterization workflows and quality control assays for discovery stage Requirements ~ Ph.D. in pharmaceutical sciences, chemistry, chemical engineering, bioengineering, or biochemistry ~2+ years post-doctoral... 
    Senior

    Gilead Sciences

    Foster, CA
    11 days ago
  • $168.1k - $312.3k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...We're looking for a talented Senior Scientist who combines strong... 
    Senior
    Full time
    Local area
    Worldwide

    Genentech

    South San Francisco, CA
    2 days ago
  • $278.53k - $345.04k

     ...creator ecosystem.In search and discovery, you will contribute to the...  ....Balance researching new technologies with a practical approach to...  ...+ (for principal) or 4+ (for senior) years of experience designing...  ...a BS, MS, or PhD in Computer Science or a related discipline or equivalent... 
    Senior
    Full time
    Work experience placement
    H1b
    Work at office
    Local area
    Visa sponsorship
    Monday to Friday

    Roblox

    San Mateo, CA
    4 days ago
  • $193.5k - $283.8k

     ...waiting. We unite caring with discovery to help make life better for...  ...traditionally block bold science from becoming life-changing...  ...integrate breakthrough science and technology - including the rapidly...  ...Summary The LV Tech group seeks a Senior Director to execute the group’s... 
    Senior
    Full time
    Visa sponsorship
    Work visa
    Flexible hours

    100 Eli Lilly and Company

    South San Francisco, CA
    3 days ago
  • $147.6k - $274k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...suggestions for improvements.Senior Machine Learning Engineer - DevOpsLead... 
    Senior
    Full time
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    4 days ago
  • $167.4k - $310.8k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...are seeking a highly motivated Senior Machine Learning Scientist to... 
    Senior
    Full time
    Local area
    Worldwide
    Relocation package
    Shift work

    Genentech

    South San Francisco, CA
    4 days ago
  •  ...Gilead Sciences seeks a Senior People Technology Product Manager to lead Workday implementation and optimization within HR. This role combines deep technical expertise with solution architecture to deliver scalable HR technology solutions supporting global process standardization... 
    Senior

    Gilead Sciences

    Foster, CA
    11 days ago
  • $261.38k - $338.25k

     ...This job is with Gilead Sciences Inc., an inclusive employer and a member of myGwork –...  ...Gilead's team plays a critical role in the discovery and development of life-changing...  ...medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who... 
    Senior
    Full time
    Worldwide

    Gilead Sciences Inc.

    Foster, CA
    2 days ago
  • $190k - $220.15k

     ...by Priscilla Chan and Mark Zuckerberg to harness the power of technology to pursue some of society’s most ambitious goals — from curing...  ...Learning Commons. Whether enabling scientific breakthroughs via open science and AI-powered biology or strengthening the tools teachers and... 
    Senior
    Work at office
    Relocation package
    Shift work
    3 days per week

    Chan Zuckerberg Initiative

    Redwood City, CA
    2 days ago
  • $201.3k - $373.8k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...can present complex science to senior leadership and collaborate across... 
    Full time
    Local area
    Worldwide
    Shift work

    Genentech

    South San Francisco, CA
    2 days ago
  • $302.4k

     ...innovation and excellence. SIE is a dynamic technology company, delivering cutting-edge...  ...entertainment excellence and creativity.Senior Director, PatentsSan Mateo, CA | Hybrid - 2 days...  ...degree in electrical engineering, computer science, or other area relevant to IP practice... 
    Senior
    Private practice
    Work at office
    Relocation package
    2 days per week

    Sony Interactive Entertainment America

    San Mateo, CA
    1 day ago
  • $177k - $235k

     ...We Are:Calico (Calico Life Sciences LLC) is an Alphabet-founded...  ...mission is to harness advanced technologies and model systems to...  ...commitment to curiosity-driven discovery science, and, with academic...  ...We are seeking an innovative Senior Scientist / Principal Scientist... 
    Senior

    Calico Life Sciences

    South San Francisco, CA
    4 days ago
  • $236.2k - $413.7k

    About UsVisa is a world leader in payments technology, facilitating transactions between...  ...position requires close collaboration with senior leaders across various departments to ensure...  ...product managers, marketing, data science, data engineering and technology teams.... 
    Senior
    Full time
    Work experience placement
    Work at office
    Local area
    Work visa
    Flexible hours

    Visa

    Foster, CA
    4 days ago
  • $201.3k - $373.8k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...scientific structure in which senior scientists define their own research... 
    Full time
    Work experience placement
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    5 days ago
  • $192.5k - $357.5k

     ...us to innovate. To continuously advance science and ensure everyone has access to the...  ...computational sciences are transforming drug discovery and development. Roche’s Research and...  ...(pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel... 
    Full time
    Local area
    Worldwide
    Relocation package

    Genentech

    South San Francisco, CA
    2 days ago
  • $144.9k - $269.1k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...methods to study these pathways (Senior Scientist). Additionally,... 
    Senior
    Full time
    Local area
    Worldwide
    Relocation package
    3 days per week

    Genentech

    South San Francisco, CA
    5 days ago
  • $281.01k - $363.66k

     ...Gilead Sciences seeks a Senior Director to lead medical affairs strategy for its inflammation pipeline, managing a team of 3-6 professionals. The role involves developing medical affairs capabilities, collaborating across functions on clinical and commercialization strategies... 
    Senior

    Gilead Sciences

    Foster, CA
    11 days ago
  • $147.8k - $274.4k

     ...innovate. To continuously advance science and ensure everyone has...  ...sciences are transforming drug discovery and development. Roche’s...  ...have demonstrated how these technologies accelerate R&D, leveraging data...  ...motivated and collaborative Senior/Principal Machine Learning Scientist... 
    Senior
    Full time
    Local area
    Worldwide

    Genentech

    South San Francisco, CA
    1 day ago
  • $193k - $231k

     ...supporting ecosystem required to bring this technology to market. Sitting at the intersection...  ...highly execution-oriented team.As the Senior Technical Program Manager (TPM) for Vehicle...  ...’s degree in Engineering, Computer Science, or a related technical field (or equivalent... 
    Senior
    Full time
    Temporary work
    Local area
    Immediate start
    Relocation package
    Shift work

    Zoox

    San Mateo, CA
    4 days ago
  • $163.6k - $245.4k

     ...innovation and excellence. SIE is a dynamic technology company, delivering cutting-edge...  ...entertainment excellence and creativity.Senior Technical Program Manager, MobileSan Mateo...  ...Qualifications:• Bachelor's degree in Computer Science, Engineering, or related technical field... 
    Senior
    Worldwide
    Flexible hours

    Sony Interactive Entertainment America

    San Mateo, CA
    5 hours ago
  •  ...Gilead Sciences seeks a Senior Director to lead real-world evidence strategy for inflammation therapeutics across development and commercialization stages. This role manages observational research teams, partners cross-functionally with clinical and regulatory stakeholders... 
    Senior

    Gilead Sciences

    Foster, CA
    11 days ago
  • $205.62k - $266.09k

     ...cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great...  ...tomorrows. Job Description Position Summary The Senior Director, Integrated Insights (US) reports to the Executive Director... 
    Senior
    Full time
    For contractors
    Local area

    Gilead Sciences

    Foster, CA
    16 days ago
  •  ...lives every day. Each of us believes that science can change lives and to deliver this...  ...responsibility for the value chain from discovery through to late-stage development and...  ...customer, and competitor analytics. The Senior Director, Global Analytics & Insights, Cell Therapy... 
    Senior

    AstraZeneca

    South San Francisco, CA
    2 days ago
  • $145k - $180k

     ...We Are:Calico (Calico Life Sciences LLC) is an Alphabet-founded...  ...mission is to harness advanced technologies and model systems to...  ...commitment to curiosity-driven discovery science and, with academic and...  ...Description:Calico is seeking a Senior/Principal Environmental... 
    Senior
    For contractors
    Work at office

    Calico Life Sciences

    South San Francisco, CA
    3 days ago
  • $252.8k

     ...are excited to be hiring a Senior Director of Global Litigation Management...  ...for the cost-efficient, technology-enabled, and high-quality delivery...  ...partnering on fact-finding, discovery, eDiscovery and information...  ..., biotechnology, or life sciences industry experience is a strong... 
    Senior
    Temporary work
    Local area
    Remote work
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    2 days ago
  • $230k - $240k

     ...We Are:Calico (Calico Life Sciences LLC) is an Alphabet-founded...  ...mission is to harness advanced technologies and model systems to...  ...commitment to curiosity-driven discovery science and, with academic and...  ...Calico is seeking an Associate Director, Medical Writing to provide... 
    Work at office

    Calico Life Sciences

    South San Francisco, CA
    4 days ago
  • $135.4k - $203.2k

     ...Illumina, we are expanding access to genomic technology to realize health equity for billions of...  ...world. Our efforts enable life-changing discoveries that are transforming human health...  ...The estimated base salary range for the Senior or Staff Scientist, Perturb-seq - Foster... 
    Senior
    Full time
    Local area
    Worldwide

    Illumina

    Foster, CA
    2 days ago
  • $145k - $190k

     ...healthcare industry?Recent advancements in underlying technology have finally made it possible for AI to impact...  ...time.We are seeking a motivated and talented Senior Scientist II to join the Computational Discovery Science team. This scientist will contribute to a team... 
    Senior
    Full time
    Work experience placement
    Remote work
    Shift work

    Tempus

    Redwood City, CA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Director, Discovery Sciences & Technologies. Be the first to apply!