Associate Scientist, DMPK
$35.35 - $47.34 per hourNeurocrine Biosciences
Who We Are: Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie) About the Role: Performs research and/or development in collaboration with others on in-vivo and in-vitro pharmacokinetics, pharmacodynamics and drug metabolism studies working with clinical pharmacology, drug metabolism and therapeutics areas. Assists in the quantitative evaluation of new products and maintenance of existing pharmacokinetics and drug metabolism product lines through the application of state-of-the-art knowledge in pharmacokinetics, pharmacodynamics and bioanalytical chemistry. Provides support in the outsourcing and conduct of in vitro drug metabolism and permeability assessments to support early drug discovery efforts. Participates in review and QC of study reports that are part of regulatory submission packages. _ Your Contributions (include, but are not limited to): Plan, write study protocols, and conduct controlled experiments to characterize toxicological and PK properties of new investigational drugs. Collect, analyze, communicate results, and assist in preparing reports in a timely manner Work collaboratively with other scientists, technicians and colleagues as part of multidisciplinary project teams Understand and interpret study protocols/SOP's to ensure that the tasks are conducted accurately Prepare dose formulations and other reagents as instructed Other duties may be assigned as necessary Requirements: BS/BA degree AND some relevant experience preferred Able to execute experiments efficiently and suggest small process improvements Able to recognize patterns or inconsistencies in data results Able to deduce meaningful results while conducting routine analyses or troubleshoot minor issues. Good knowledge of one scientific discipline Developing knowledge of scientific principles, methods and techniques Good knowledge and some experience working with discipline specific laboratory equipment/tools Ability to work as part of a team Good computer skills Developing communications, problem-solving, analytical thinking, planning and organization skills Detail oriented Understands importance of meeting deadlines #LI-LS1 Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. _ The hourly rate we reasonably expect to pay is $35.35-$47.34. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 15% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. We are a top place to work. Neurocrine Biosciences was named one of the FORTUNE Best Workplaces in Biopharma™ 2025. We were also named a Great Place to Work® Certified company. ©2025 Fortune Media IP Limited. All rights reserved. Used under license. OUR VALUES: PASSION: We are driven and love what we do. We are committed to our goals and to making a difference. INTEGRITY: We do the right thing for patients and our community. We take accountability. We speak up. COLLABORATION: We trust one another. We are inclusive. We are respectful. We are transparent. Together we succeed. INNOVATION: We seek and create optimal solutions. TENACITY: We do not quit. We adapt. We accomplish what others cannot. Come join our team during this exciting time of growth and opportunities!
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About the Role We are looking for a collaborative and highly motivated senior scientist to join our biotransformation and metabolism group. The primary role will be to support in vitro and in vivo metabolite identification for multiple discovery and development projects...- Neurocrine Biosciences is seeking a senior scientist in San Diego to join the biotransformation and metabolism group. The role involves conducting in vitro and in vivo metabolite identification, optimizing methods, and preparing detailed reports. Ideal candidates should...
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$130.8k - $179k
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Job Description Purify reagent proteins/antibodies using gravity or chromatography-mode with various FPLC methods (affinity, ion exchange, and gel filtration) under supervision. Apply protein chemistry/analytical techniques such as mass spectrometry, SDS-PAGE, and analytical...Hourly payFull timeMonday to FridayFlexible hours$140k - $155k
...Principal Scientist – BioProcess Development San Diego, CA, USA (92121) The Principal Scientist, BioProcess Development is a senior technical leadership role responsible for the design, development, optimization, and scale‑up of bioprocesses for plasmid DNA, protein biologics...Permanent employmentContract workCasual workFlexible hours$110.8k - $151k
...includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal... ...design optimized compounds with balanced properties (targets, DMPK, in-vivo) in drug discovery programs. Provides impactful insights...Full time- ...you’re working to help others.**Position Overview**The Research Scientist, with limited guidance from more experienced scientists, works... ...and department goals.* Ability to train and mentor research associates.* Ability to organize, present, and convey moderate problems or...Local areaNight shift
$85k - $115k
...Research Scientist III / Senior Research Scientist About Us Sapient is an early-stage fee for service, contract research organization in San Diego, CA. Our focus is on accelerating drug development and transforming personalized medicine for our pharma and biotech clients...Full timeContract workWork experience placement- ...Job Title: Research Scientist | Location: San Diego, CA (Onsite role) | Duration: 18 months | Pay Rate: ***/hour - ***/hour Our Global Genetically Engineered Models (GEMs) Team within Comparative Medicine (CM) supports the expansion of animal science, preclinical care,...Flexible hours
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