Manager, Disease Strategy Finance

Manager within Vertex's Disease Strategy Finance team responsible for conducting financial modeling, forecasting, and scenario-based valuations to support disease strategy decisions. The role involves creating annual budgets, long-term plans, and managing disease area P&Ls while partnering across the finance and CFO organizations.

Responsibilities

• Prepare financial analyses and valuations to inform disease strategy team investment decisions
• Lead preparation of alliance and collaboration financials for revenue and cost sharing arrangements
• Develop and maintain financial models across research, development, manufacturing, and commercialization phases
• Manage disease area P&Ls including variance analysis, risk identification, and mitigation opportunities
• Prepare presentations for cross-functional stakeholders and senior leadership on financial topics

Requirements

• B.S. in Finance, Economics, or related quantitative field; MBA preferred
• 5+ years of finance and industry experience in biotechnology or pharmaceutical sector
• Understanding of biopharmaceutical drug research, development, manufacturing, and commercialization
• Advanced Excel and PowerPoint skills; experience with Hyperion or business intelligence tools a plus
• Exceptional analytical abilities in valuation, ROI/ROIC, and complex business decision evaluation
• Strong written and verbal communication with ability to collaborate across organizational levels

Compensation: $116,000 - $174,000 base