Clinical Trial Manager

Absci seeks an experienced Clinical Trial Manager to lead end-to-end operational execution of Phase II-III global clinical trials. The role requires independent management of complex studies from startup through closeout, with oversight of CROs, sites, and internal cross-functional teams to ensure compliance, quality, and efficiency.

Responsibilities

• Independently manage all operational aspects of assigned global clinical trials through protocol adherence and regulatory compliance
• Oversee CRO and vendor performance, including monitoring visit reviews and Trial Master File quality control
• Develop and execute study-level operational plans covering recruitment, retention, monitoring, and risk management
• Partner with legal and finance teams on budgets, contracts, insurance, and data protection protocols
• Communicate trial progress, compliance metrics, and findings to internal and external stakeholders

Requirements

• Proven experience independently managing Phase II-III clinical trials from startup to closeout
• Strong knowledge of clinical trial operations, regulatory requirements, and ethical standards
• Demonstrated ability to oversee CROs, vendors, and investigator sites effectively
• Experience with clinical data management, risk mitigation, and operational documentation
• Excellent cross-functional collaboration and stakeholder communication skills
• Analytical and problem-solving abilities with proactive risk identification