Senior Scientist: Protein Therapeutics Characterization (MS)
$147k - $191kDenali Therapeutics
Denali Therapeutics, located in South San Francisco, is seeking a talented Senior Scientist to lead protein characterization initiatives within our large molecule CMC analytical development group. This role requires expertise in mass spectrometry-based methods and a PhD in a relevant scientific field, with a strong commitment to developing therapies for neurodegenerative diseases. Compensation ranges from $147,000 to $191,000, alongside a competitive benefits package including healthcare and 401k. #J-18808-Ljbffr Denali Therapeutics
$147k - $191k
Denali Therapeutics Inc in South San Francisco seeks an experienced professional to lead mass spectrometry and characterization activities for large molecule CMC. The role involves developing strategies for product characterization, maintaining lab records, and overseeing...Senior$147k - $191k
...of our time. Denali Therapeutics is a biotechnology company... ...of leading scientists, industry experts, and... ...talented and motivated Senior Scientist with a strong background in characterizing protein therapeutics using mass... ...technical execution of LC-MS based...SeniorLocal area$140k - $160k
Scientist / Sr Scientist - Therapeutic Discovery (Protein Engineering) 3T Biosciences is solving a major bottleneck in the field of immunotherapy - identifying... ...bi/multispecific design, screening, and characterization to support development candidate nomination against...Senior$140k - $250k
...Principal Scientist, Protein Sciences, Analytical Characterizations September 2025 Department: Technology Position Summary... ...and antibody focused pre-clinical therapeutic pipeline. The ideal candidate... ...biologicswith an emphasis on LC-MS and biophysical characterization...SuggestedFull timeTemporary workFlexible hours$140k - $160k
3T Biosciences, Inc. is hiring a Scientist / Sr Scientist in South San Francisco to enhance therapeutic discovery in immuno-oncology. This role involves designing and managing antibody lead discovery and optimization against novel peptide-HLA targets, utilizing yeast display...Senior- ...Description The Biosciences’ Protein Sciences Group within Lead Discovery... ...motivated Contract Research Scientist to lead the development and... ...development of novel cancer therapeutics in a fast‑paced,... ...protein‑protein interactions (IP‑MS, XL‑MS, Bio‑ID) Experience with...SeniorContract workFlexible hoursShift work
- Senior Scientist Experimental Protein Design for Target Discovery What you will do In this vital role you... ..., experimental validation, and characterization of computationally designed de novo... ...and accelerate early-stage therapeutic discovery. Key Responsibilities...SeniorFlexible hours
- Senior Scientist, Membrane Protein Biochemistry What You Will Do In this vital role you will be part of... ...purification, and detailed analytical characterization. The role will also include... ...large‑molecule and small‑molecule therapeutic discovery programs. Key Responsibilities...SeniorFlexible hours
$168.6k - $313k
...motivated and experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative research and... ...position within our Peptide Therapeutics department, focused on advancing Peptide... ...(e.g., OBOC, mRNA display, AS/MS). Computational Methods: Experience...SeniorLocal areaRelocation package- Senior Scientist - LCMS Bioanalysis What you will do In this... ...and apply innovative LC‑MS‑based bioanalytical assays to quantify therapeutic candidates, assess... ...engagement and modulation, characterize target dynamics, and... ...multispecific molecules, targeted protein degradation platforms,...Senior
$135k - $180k
...quality control oligos using HPLC/UPLC, LC-MS, MALDI, UV quantification, PAGE,... ...Who You Are Hands‑on experience with RNA therapeutics, ASOs, siRNA, splice‑switching oligos, RNA... ...knockdown or splice correction, transcript and protein‑level readouts, pathway modulation, cell...SeniorH1bVisa sponsorship- Genentech in South San Francisco is seeking a Scientist III to join Translational Medicine. You will help identify and validate therapeutic targets and biomarkers using human clinical... ...with mechanistic understanding across MS-related biology. The role demands expertise...Senior
- Amgen is seeking a Senior Scientist in South San Francisco to lead the development of LC-MS bioanalytical assays. This role involves collaborating with cross-functional teams to support therapeutic candidates from preclinical development to regulatory submissions. The...Senior
- A bio-innovation firm in San Francisco is seeking a Machine Learning Scientist to lead research initiatives and innovate protein design methodologies. The ideal candidate will drive research on AI applications in protein design, with responsibilities including project leadership...Senior
$167.88k - $178.5k
Senior Scientist II - CMC Developmental Sciences Full-time... ...lives across several key therapeutic areas - immunology,... ...line development, characterization studies, cell culture... ...process development, or protein purification to... ...Experience Must have a MS in Cell & Molecular Biology...SeniorFull timeTemporary workWork experience placement$131.4k - $206.8k
...seeking a highly motivated Senior Scientist to join our Protein Expression and... ...in the discovery of novel therapeutics through design and execution... ...protein purification and characterization techniques. · Experience... ...(industry preferred); or MS with 4+ years /BS with 7+...SeniorFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$96.5k - $183.5k
Senior Scientist I, Cell Line Development Full-time Salary... ...lives across several key therapeutic areas including... ...understanding of recombinant protein expression to improve... ...screening, and clone-characterization studies to generate... ...of 10 years, or MS with a minimum of 8 years...SeniorFull timeTemporary work$169.32k - $219.12k
..., together. Job Description The Protein Therapeutics Department at Gilead Sciences is seeking a highly motivated Senior Scientist to join our Biologic Engineering team... ...including identification, screening, and characterization of candidate molecules. Integrate...SeniorFull timeFor contractorsLocal area- Initial Therapeutics, Inc. is seeking a Senior Scientist in South San Francisco to lead efforts in transforming computational protein designs into validated binders and antibodies. Responsibilities include developing high-throughput platforms to generate and validate new...Senior
- Amgen is seeking a Senior Scientist specializing in Membrane Protein Biochemistry in South San Francisco. The role involves designing strategies for membrane... ...equivalent, with experience in membrane protein characterization and strong communication skills. Amgen offers a...Senior
$156.29k - $166.24k
Job Title Protein Analytics Scientist Location 1000 Sierra Point Parkway, Brisbane... ...using a variety of characterization techniques such as mass spectrometry... ...and optimization of therapeutic antibodies. Conduct epitope... ...edge technologies such as LC‑MS, SEC‑MALS, glycan analysis...Temporary workWork experience placementSummer workRemote workFlexible hours- ...biotechnology firm in South San Francisco is seeking a highly motivated Senior Scientist in Bioanalytics. The candidate will lead bioanalytical... ...a Ph.D. with 7+ years experience or equivalent, strong LC-MS knowledge, and excellent communication skills. The anticipated...Senior
- Merck's Discovery Biologics in South San Francisco seeks a Senior Scientist in Protein Sciences to design and execute molecular interaction assays that accelerate biologics discovery and optimize next‑generation modalities. You will work at the bench, independently plan...Senior
$115k - $135k
Associate Scientist, Protein Sciences Headquarters Location: South San... ...Required: 5-10% Reports To: Senior Scientist II Department:... ...methods—including LC-MS—to characterize these novel molecules. Additionally... ...teams to transition therapeutic programs from discovery to...Full timeRelocation$162k - $189k
## Senior Scientist IApplylocations: South San Francisco, Californiatime... ...the development of novel therapeutics and to work in a dynamic and... ...design and execution of process characterization and fate/purge studies to... ..., such as HPLC, LC-MS, and NMR to support process...Senior- ...diseases. With our focus on four therapeutic areas - Oncology,... ...transforming your career. Senior Scientist - siRNA Bioanalysis & Mechanistic... ...in vitro and in vivo, for characterizing ADME and elucidating... ...hybridization assays), LC/MS bioanalytical platforms, and...SeniorFlexible hours
- ...diseases. With our focus on four therapeutic areas - Oncology,... ...transforming your career. Senior Scientist - siRNA Bioanalysis & Mechanistic... ...in vitro and in vivo, for characterizing ADME and elucidating... ...hybridization assays), LC/MS bioanalytical platforms, and...SeniorFlexible hours
- Amgen is seeking a Scientist specializing in Membrane Protein Biochemistry at their South San Francisco facility. The successful candidate will design... ...proteins, collaborating on innovative solutions for therapeutic discovery. Applicants should possess a Ph.D. or relevant...
- Amgen is seeking a Senior Scientist specializing in Computational Protein Design in South San Francisco. This role focuses on developing automated computational pipelines aimed at enhancing drug discovery efforts. Ideal candidates have a strong background in computational...Senior
$170k - $233k
A biotechnology research firm in South San Francisco is seeking a machine learning research scientist to develop innovative algorithms for protein design. The role involves collaborating with experimental biologists and requires a Ph.D. in a relevant field or a Master'...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Scientist: Protein Therapeutics Characterization (MS). Be the first to apply!
- scientist antibody discovery South San Francisco, CA
- protein scientist South San Francisco, CA
- lead scientist South San Francisco, CA
- applied sports scientist South San Francisco, CA
- deep learning scientist South San Francisco, CA
- lab scientist South San Francisco, CA
- principal scientist South San Francisco, CA
- molecular biology scientist South San Francisco, CA
- senior analytical scientist South San Francisco, CA
- decision scientist South San Francisco, CA

