Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Scientist, mRNA-tLNP Analytics for In Vivo CAR-T

Mass Digital Health

Kernal Biologics, Inc. is seeking a Principal Scientist, Analytical Development for its Boston hub. You will lead design, development, and execution of analytical methods to support the mRNA platform and in vivo CAR-T programs, with emphasis on biophysical characterization and antibody-targeted LNPs. Ideal candidates bring deep expertise in analytical sciences, regulatory submissions, and fit-for-purpose method development and validation aligned with phase-appropriate requirements. #J-18808-Ljbffr Mass Digital Health

Vacancy posted 4 days ago
Similar jobs that could be interesting for youBased on the Principal Scientist, mRNA-tLNP Analytics for In Vivo CAR-T in Boston, MA vacancy
  • Kernal Biologics, Inc. in Boston, MA is seeking a Principal Scientist, Analytical Development to lead the design, development, and execution of analytical methods for its in vivo mRNA platform. The role emphasizes biophysical characterization and in vitro assay development... 
    Principal

    Kernal Biologics

    Boston, MA
    3 days ago
  •  ...Principal Scientist, mRNA-tLNP Analytical DevelopmentBoston, MAPrincipal Scientist, mRNA-tLNP Analytical DevelopmentAbout Kernal Biologics, Inc.Kernal...  ...lipid nanoparticle (tLNP) technology. By developing in vivo CAR-T therapies, Kernal Bio is advancing precision... 
    Principal
    Car
    Flexible hours

    Kernal Biologics Inc.

    Boston, MA
    2 days ago
  • $108.5k - $201.5k

     ...leader in field of Physical Chemistry Analytics (PCA) and Mass Spectrometry (MS) to join...  ...modalities.Job DescriptionInternal Job Title: Principal Scientist I/IIPosition Location:Cambridge, MA,...  ...Abs, AAV, ADCs, oligonucleotides, CAR-T’s. This entails the evaluation of novel... 
    Principal
    Car
    Full time

    Novartis

    Cambridge, MA
    2 days ago
  • $126k - $234k

     ...including targeted therapies, immunotherapies, CAR-T, and radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in Cambridge...  ...ELISA, western blot, and flow cytometryStrong analytical, communication (written and verbal), and... 
    Principal
    Car
    Full time
    Remote work

    Novartis

    Cambridge, MA
    13 hours ago
  • $142.5k - $256.5k

     ...accomplished and highly motivated Principal Scientist to join the Antibody...  ...cell engagers, TCR engagers, CAR-T-related formats, and other...  ...expression, purification, and analytical characterization.Expertise...  ...aspired to build the leading mRNA technology platform, the infrastructure... 
    Principal
    Car
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    3 days ago
  • $160k - $190k

     ...Position The Principal Scientist, Analytical Chemistry will report directly to the Director of Oligonucleotide and Conjugation Chemistry and will interface...  ...and distribution of oligonucleotides and conjugates in vivo. Assist in internal lab build, procuring and utilizing... 
    Principal

    Raven Healthcare Incubator (RA Capital)

    Boston, MA
    1 day ago
  •  ...inside the body using AI-designed, selective mRNA and targeted lipid nanoparticle (tLNP) technology. By developing in vivo CAR-T therapies, Kernal Bio is advancing...  ...for manufacturing, process development, and analytical development of mRNA-tLNP therapeutics. The... 
    Car
    Contract work
    Flexible hours

    Mass Digital Health

    Boston, MA
    3 days ago
  • $142.5k - $256.5k

     ...talented, experienced, and highly motivated Principal Scientist to support computational protein design...  ...liabilities, and compatibility with mRNA-expressed therapeutic formats.Help build...  ...catalysts, DNA- or RNA-binding proteins, CAR signaling domains, engineered scaffolds,... 
    Principal
    Car
    Permanent employment
    Full time
    Work at office
    Work from home

    Moderna Therapeutics

    Cambridge, MA
    2 days ago
  •  ...Johnson & Johnson Innovative Medicine is seeking outstanding scientists and leaders to join the Real‑World Evidence & Advanced Analytics team in Cambridge, MA. You will lead a portfolio of RWE projects, develop tools to accelerate delivery, and guide end‑to‑end studies... 
    Principal

    Johnson & Johnson Innovative Medicine

    Cambridge, MA
    18 hours ago
  • $160k - $190k

    Raven in Cambridge, MA is looking for a Principal Scientist in Analytical Chemistry to develop analytical methods for oligonucleotide therapeutics. You will work closely with cross-functional teams to advance therapeutic programs. Candidates should have a PhD in chemistry... 
    Principal

    Raven

    Boston, MA
    2 days ago
  •  ...what's possible in genetic medicine and work to make a lasting impact on human health. Korro Bio is seeking an experienced analytical scientist to join the growing CMC team. You will focus on management of CMO analytical labs as well as development of analytical... 
    Principal
    Flexible hours

    Korro Bio

    Cambridge, MA
    more than 2 months ago
  • $71.25k - $187k

     ...beyond. Position Summary We are seeking an exceptional Senior Principal Scientist to join our growing team. In this role, you will partner...  ...with Platform Science, Discovery, and CMC groups to drive analytical characterization of circular RNA and lipid nanoparticle‑based... 
    Principal
    Full time
    H1b
    Visa sponsorship
    Work visa
    Flexible hours

    BioSpace

    Watertown, MA
    2 days ago
  • $66.8k - $124k

     ...MA is seeking a highly motivated Research Scientist with experience in production and...  ...contributing to groundbreaking research in CAR-T cell therapy. About the Role...  ...focused on lentiviral vector purification and analytics, you will apply hands-on laboratory expertise... 
    Car
    Relocation package

    Research

    Cambridge, MA
    4 days ago
  • $138.4k - $207.6k

    Job Description General Summary The Analytical Science and Technology (AS&T) Principal Scientist, Separation Method Expert, will be responsible for providing scientific and technical expertise within and across functional areas for late‑stage & commercial methods and vendor... 
    Principal
    Contract work
    Work experience placement
    Summer work
    Remote work
    Worldwide
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals Incorporated

    Boston, MA
    2 days ago
  • $117k - $201.25k

     ...searching for exceptional candidates for a Principal Scientist, Spatial Omics, role as part of...  ...discoveries in relevant in vitro and ex vivo disease models and to collaborate closely...  ...stage data mapping, QC frameworks, and analytical handoffs to computational teams. Qualifications... 
    Principal
    Full time
    Local area
    Immediate start

    Johnson & Johnson Innovative Medicine

    Cambridge, MA
    1 day ago
  • $120k - $160k

     ...Every employee contributes to the success of the company and you can be part of that team. Job Summary The QC Senior/Principal Scientist for Analytical Method Validation is a key role within our Quality Control Technical Services (QCTS) department within our CDMO facility... 
    Principal
    Immediate start
    Visa sponsorship

    Genezenlabs

    Lexington, MA
    4 days ago
  • $145k - $161k

     ...exceptionally driven, discovery-minded Senior Scientist to join our Platform Technology &...  ...bring deep expertise in RNA biology and mRNA engineering, a rigorous and creative scientific...  ..., translational efficiency, and in vivo performanceDesign and execute well-controlled... 
    Full time
    Temporary work

    Prime Medicine

    Cambridge, MA
    4 days ago
  •  ...SummaryWe are seeking a highly motivated Senior Scientist with expertise in LC-MS-based antibody/...  ...candidate will perform hands-on analytical research focused on antibody-drug conjugates...  ...ADC metabolites from in vitro and in vivo studies using analytical techniques such... 

    Planet Pharma

    Boston, MA
    1 day ago
  • $179k - $200k

     ...integrity and project success by interpreting analytical results to confirm compound quality....  ...-based screening technologies (DEL, mRNA display , phage display) and direct experience...  ...with a talented and passionate team of scientists ~ Be a part of a cutting-edge... 
    Principal

    Psivant Therapeutics, Inc.

    Watertown, MA
    4 days ago
  • $154.4k - $242.55k

     ...information I submit in my employment application is true to the best of my knowledge.Job DescriptionJoin Takeda as a The Senior/Principal Scientist, Analytical Cell Line Engineering and Bioessay Development plays a key role in managing and performing scientific research,... 
    Principal
    Minimum wage
    Temporary work
    Local area
    Shift work

    Takeda

    Lexington, MA
    2 days ago
  • Moderna is seeking a Senior Scientist to drive discovery, design, and preclinical development of mRNA-based cancer immunotherapies. You will work with in vitro/ex vivo systems and design in vivo studies, mentoring junior staff and presenting data in cross-functional settings... 

    Socket.dev

    Cambridge, MA
    3 days ago
  • Moderna is seeking a Senior Scientist to lead computational efforts in translational bioinformatics for mRNA therapeutics and vaccines. You will apply advanced analytics to bulk and single-cell data, TCR/BCR repertoires, and multi-omics to uncover targets, mechanisms, and... 

    BioSpace

    Cambridge, MA
    4 days ago
  •  ...Massachusetts is looking for a skilled professional to manage mRNA production and serve as the primary liaison for mRNA requests across...  ...involves executing production processes, collaborating with Analytical and QC teams, and conducting statistical analyses to support... 

    Primemedicine

    Cambridge, MA
    4 days ago
  •  ..., collaborative and resourceful scientist/senior scientist with extensive experience in CAR-T and T cell biology. The successful...  ...teams including delivery, analytical, pharmacology, and manufacturing...  ...cell expansion, flow cytometry, ex-vivo processing, etc). Previous... 
    Car
    Full time

    Typewriter Therapeutics, Inc.

    Cambridge, MA
    13 hours ago
  • Moderna is seeking a Senior Scientist to advance discovery, design, and preclinical development of new mRNA-based cancer immunotherapies. You will work with in vitro/ex vivo systems and design in vivo studies to characterize novel therapeutics, mentoring junior colleagues... 

    BioSpace

    Cambridge, MA
    1 day ago
  • Moderna is seeking a Senior Scientist to lead discovery, design, and preclinical development of new mRNA-based immunotherapies for cancer. The role focuses on in vitro and ex vivo systems, with in vivo study design and data interpretation. Mentoring junior scientists and... 

    Initial Therapeutics, Inc.

    Cambridge, MA
    13 hours ago
  •  ...throughput pre-clinical QC workflows in Research Analytics. This role involves executing QC assays,...  ...to workflow improvements for mRNA materials. The position emphasizes documentation...  ...integrity, and collaboration across scientists, automation engineers, and operations to... 

    Initial Therapeutics, Inc.

    Cambridge, MA
    1 day ago
  •  ...Job Description Job Description Scientist / Senior Scientist, In Vivo Pharmacology & Translational Biology Location: Boston, MA Company:...  ...-making. Collaborating cross-functionally with CMC, analytical development, and external CROs/CDMOs, and mentoring junior... 
    Full time

    Tevard Biosciences

    Boston, MA
    20 days ago
  • $118k - $178k

     ...looking for an inspiring Senior Scientist Vector Engineering to drive...  ...vector engineering, gene editing, CAR and TCR T cell engineering or...  ...to the Associate Director In Vivo Cell Therapy and be based in...  ...immunogenicity in collaboration with analytics partners.  Apply literature... 
    Car
    Full time
    Temporary work
    Work at office
    Flexible hours
    3 days per week

    AstraZeneca

    Cambridge, MA
    3 days ago
  •  ...cloning, hybridoma, surface display and direct CAR-based functional screening, Nona...  ...Biosciences is seeking a skilled and experienced scientist to join our team in Natick, MA. The...  ...Responsibilities Help to plan and execute mouse in vivo studies including immunizations, titer... 
    Car
    Worldwide
    Flexible hours

    Nona Biosciences

    Natick, MA
    3 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Scientist, mRNA-tLNP Analytics for In Vivo CAR-T. Be the first to apply!