Analytics CoE Senior Manager

Key Responsibilities: Leverage Vertex's in-licensed RWE data assets to conduct queries and analyses supporting the Vertex product portfolio and development programs across therapeutic and disease areas. Conduct feasibility assessments to inform design/execution of research projects. Conduct health economic and outcomes research to characterize disease burden, healthcare resource utilization, co-morbidities, and treatment patterns in real-world populations. Generate actionable insights to address key business questions from internal and external stakeholders. Lead development of study protocols, statistical analysis plans, and table shells. Support statistical programmers by executing data queries and analyses. Generate analytic reports, tables, and visualizations to communicate findings to internal stakeholders. Collaborate with cross-functional colleagues to improve the analytics operating model. Develop/enhance/maintain internal analytic tools (e.g., programming libraries, reusable macros, table templates). Support HEOR disease/asset leads in assessing research gaps and evidence generation objectives. Qualifications: Advanced degree in health economics or related discipline (math, statistics, economics, epidemiology). Typically 6 years of relevant experience in health economics and outcomes research (or equivalent: Doctorate + 2 years; Master’s + 4 years). Knowledge of observational research methods for studies of disease burden, resource utilization, treatment patterns, comorbidities, and outcomes. Hands-on experience analyzing large patient-level healthcare datasets (open/closed claims, EHR/EMR, hospital chargemaster; e.g., MarketScan, PharMetrics Plus, eLAAD+, Premier). Working knowledge of national healthcare coding systems (diagnostic, procedure, drug) and healthcare system structures. Advanced proficiency in SAS programming and Excel required. Excellent written and oral communication skills. Ability to plan, organize, and manage multiple projects across therapeutic areas. #J-18808-Ljbffr Scorpion Therapeutics