Vice President, Strategy and Portfolio Planning (San Francisco)

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.

Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.

We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.

THE OPPORTUNITY

Vir Biotechnology seeks a Vice President, Strategy & Portfolio Planning, reporting to the Chief Business Officer, who will be responsible for guiding the company's strategy and optimizing its portfolio of programs products, and partnerships. This visible leadership position works across all business units.

You will serve as a thoughtful strategic partner to the CBO and executive leadership team, driving corporate strategy and portfolio prioritization. You will optimize Vir Bio's business, translate enterprise-level strategies into actions, and align the organization to the strategy. Working closely with competitive intelligence, business development, and alliance management CBO sub-teams, you will develop Vir Bio's long-term strategic plan and lead integrated asset-level strategies across clinical and preclinical-stage programs. An enterprise leader, you will apply analytical rigor, translate complex clinical, scientific, and financial data into clear recommendations, articulate strategy, and work collaboratively across the company.

You’ll thrive in this role if you love shaping big-picture strategy in fast-moving biotech environments, get energized by steering clinical-stage portfolios to provide the greatest patient benefit, and leveraging your experience across organizations both large and small.

This role is in our San Francisco headquarters with at least 3 days per week in the office.

WHAT YOU'LL DO

Corporate Strategy

• Lead the development and evolution of Vir Bio's long-term strategic plan in partnership with the CBO, executive leadership, and Board of Directors
• Adapt corporate strategy in response to emerging clinical data, evolving market dynamics, and competitive landscape shifts
• Working closely with the CEO, CBO, and CEO Chief of Staff, conceptualize and create board materials for quarterly board meetings and strategic offsites
• Drive scenario planning and options analysis to inform critical business decisions and enable agile executive team decision-making
• Contribute to investor communications and narratives supporting company growth
• Design and manage strategic planning cycles, leadership meetings, and governance forums to enable clear priorities, decision-making, and execution tracking

Portfolio Planning

• Partner with the CBO and executive leadership to shape Vir Bio's long-term portfolio strategy, evaluating diversification pathways and strategic options under different capital, partnership, and market scenarios
• Define portfolio strategy frameworks and valuation methodologies (NPV analysis, risk-adjusted valuations, scenario modeling) that inform corporate development priorities, investment decisions, and strategic prioritization
• Develop and implement analytical frameworks and decision-making tools (including those leveraging AI/ML) that enhance organizational capabilities, driving data-driven strategic maturity and alignment across the organization
• Conduct portfolio-level strategic analysis to identify gaps, optimize risk profile, and maximize financial returns, influencing business development target identification and deal thesis development in close partnership with senior leadership
• Establish portfolio metrics, KPIs, and measurement frameworks to evaluate performance against strategic objectives, integrating competitive intelligence, emerging clinical data, and market insights into decision-making
• Engage external advisors, consultants, and KOLs to inform portfolio strategy and validate strategic assumptions

WHO YOU ARE AND WHAT YOU BRING

• BA/BS with 20+ years, MS/MBA with 18+ years, or PhD with 15+ years of progressive pharmaceutical or life sciences experience in senior leadership roles; experience in infectious disease and/or oncology highly preferred
• Proven track record in corporate strategy development, portfolio management, and strategic execution within or for large and small biopharmas
• Biopharma strategy consulting experience, preferably with one of the premier management consulting firms preferred
• Experience leading integrated strategy across clinical-stage programs, including portfolio prioritization, development planning, and commercial positioning
• Expertise in financial modeling, valuation methodologies (DCF, NPV, risk-adjusted valuations), and portfolio analytics
• Experience delivering strategic initiatives through governance processes and managing ambiguity

WHO WE ARE AND WHAT WE OFFER

The expected salary range for this position is $300,000 to $350,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.

Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person’s experience and qualifications. All full‑time employees receive a package that includes compensation, bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non‑accrual paid time off, company shut down for holidays, commuter benefits, 401K match and lunch each day in the office.

Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

All employment decisions at Vir Biotechnology are based on legitimate, non‑discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.

This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.

Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.

For hires based in the United States, Vir Biotechnology participates in E-Verify.

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