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Vice President, Portfolio Chemistry

Revolution Medicines

Revolution Medicines seeks a Vice President of Portfolio Chemistry to lead medicinal chemistry strategy and execution across their oncology discovery portfolio. This executive will oversee advancement of small-molecule programs from hit validation through development candidate nomination, integrating modern chemistry approaches with AI-enabled drug discovery tools.

Responsibilities

  • Lead medicinal chemistry strategy and execution for discovery portfolio advancement
  • Partner with research leadership to define long-term portfolio expansion strategy
  • Integrate computational chemistry, AI/ML, and digital drug discovery capabilities into workflows
  • Manage organizational planning, talent development, and internal/external resource allocation
  • Drive alignment across research functions and establish project leadership excellence

Requirements

  • Extensive medicinal chemistry experience in drug discovery and development
  • Demonstrated success leading multidisciplinary chemistry teams and organizations
  • Strategic expertise in portfolio management and resource allocation
  • Knowledge of computational chemistry, AI/ML applications in drug discovery
  • Experience managing external partnerships and CRO relationships
  • Track record of delivering development candidates in oncology or adjacent areas
Vacancy posted 5 days ago
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