US HEVA Rare Asset/Indication Lead

Job title: US HEVA Rare Asset / Indication Lead

• Location: Morristown, NJ

About the Job

Sanofi is an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people's lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time.

Sanofi is committed to advancing breakthroughs in cancer care and rare diseases, expanding scientific understanding and improving outcomes for patients facing these serious, often life-threatening conditions.

Through a focused and growing portfolio of innovative therapies, Sanofi aims to address critical gaps in care and deliver meaningful, potentially transformative treatment options for underserved patient communities.

We are one bold HEOR team leveraging innovative HEOR to transform patient care and access. As HEOR experts, we lead the generation and dissemination of robust, business-relevant evidence to demonstrate value and drive access to medicines. The HEVA organization is driven by five core values that define how we work and deliver impact. We operate as One Team, partnering without boundaries while pursuing a Bold Purpose through ambitious, measurable goals. Grounded in Scientific Excellence with Relevance and deep technical expertise, we embrace Innovation in Action to transform how we research and deliver Impact for People, creating meaningful outcomes for patients, the healthcare ecosystem, and our colleagues who make it all possible.

This role is accountable for leading US HEOR strategy and execution for the Rare Hemophilia portfolio - including ALTUVIIIO, QFITLIA, Eloctat & Alprolix, and Cablivi (aTTP) - serving as the primary US HEVA point of contact for the portfolio and partnering cross-functionally to drive the generation, translation, and dissemination of high-quality, decision-relevant evidence to support access in the United States

About Sanofi

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main responsibilities:

Strategic Business Impact

• Develop and implement US payer-specific HEVA strategy in close collaboration with cross-functional team members to lead/implement VEST team structure for rare hemophilia portfolio.

• Drive measurable business impact through execution of HEVA tactics that directly support commercial objectives and market access goals compliantly and efficiently.

• Execute comprehensive US HEVA tactics for the Rare Hemophilia portfolio, contributing to strategic planning and ensuring alignment with broader portfolio objectives

• Partner with commercial teams to translate HEVA insights into actionable business strategies

• Partner with access and medical team members to generate and disseminate actionable high-impact evidence

• Develop business-relevant US research agendas through cross-functional input and alignment, ensuring evidence priorities are reflected in broader Sanofi planning documents

Internal Partnerships and Senior Management Engagement

• Build and maintain strong relationships with cross-functional teams to ensure pricing and access decisions are aligned with the demonstrable value of the Rare Hemophilia portfolio

• Align closely with the Global HEVA team to ensure US insights inform global strategies and coordinate evidence generation, modeling, and evidence synthesis activities

• Communicate complex health economics concepts and strategic recommendations to cross-functional stakeholders with clarity and impact

• Influence key business decisions through data-driven insights and strategic HEVA recommendations

• Ensure clinical development plans for Rare Hemophilia indications are designed to deliver true differentiation aligned to Sanofi's best-in-class or first-in-class ambition

Health Economics Research and Evidence Generation

• Health Economics Research and Evidence GenerationOversee the design, execution, and publication of high-quality health economics and outcomes research studies - including economic modeling, database analysis, observational research, systematic literature review, evidence synthesis, and AMCP dossier development - for the Rare Hemophilia portfolio

• Contribute to the development of comprehensive real-world evidence strategies that support product lifecycle management

• Ensure scientific rigor and regulatory compliance across all HEVA tactics

• Support the development of global launch strategies and provide strategic HEVA input into Integrated Evidence Generation Plans (IEGPs) for Rare Hemophilia indications to ensure alignment across clinical, real-world evidence, and value demonstration objectives

• Execute all HEVA tactics at the highest level of quality to compliantly further HEOR evidence dissemination, application, and proactive and/or promotional use with US stakeholders (HCEI, PIE)

• Apply data-driven decision-making frameworks to prioritize evidence gaps and guide research investment decisions for the Rare Hemophilia portfolio, ensuring alignment between identified data gaps and strategic evidence generation priorities.

Stakeholder Engagement and External Partnerships

• Represent Sanofi at major scientific conferences and industry forums, leading abstract development and presentation delivery for the Rare Hemophilia portfolio

• Collaborate with external research partners and key opinion leaders to advance HEVA strategy and tactical plans in Rare Disease

• Manage the US HEVA budget for the Rare Hemophilia portfolio, overseeing vendor contracts, research investments, and resource allocation to ensure delivery of evidence generation priorities within budget constraints

• Work with the team lead to engage with external evidence bodies (ICER, PDAB, IRA) and apply knowledge of their requirements to shape evidence generation and value demonstration strategies for Rare Disease

About you

Education & Experience

• Required: Advanced degree (PhD, MD, MSc, MPH, or PharmD) in health economics, epidemiology, public health, economics, pharmacy, or a related field

• Experience: 3-5 years of experience in health economics, outcomes research, or a related field

• Experience in rare disease therapeutic areas preferred, including understanding of disease areas, treatment paradigms, and market dynamics

Technical Skills

• Demonstrated experience in applying various HEOR methods and understanding the principles of evidence-based medicine and clinical research; strong publication record is a strong plus

• Knowledge of global HTA processes and guidelines

• US launch experience preferred; understanding of US payer evidence requirements and value demonstration in a competitive market

• Understanding of US healthcare system and payer dynamics, with ability to translate evidence into strategic insights

• Experience supporting market access and reimbursement through HEVA evidence (e.g., value tools, evidence summaries, AMCP dossier contributions)

• Working knowledge of US evidence dissemination (HCEI/PIE, reactive/proactive, CFL)

• Experience in rare disease therapeutic areas preferred, including understanding of disease areas, treatment paradigms, and market dynamics

• Experienced in statistical analysis methods relevant to HEOR, including ability to critically evaluate and apply quantitative evidence to support value demonstration and payer engagement

• Foundational knowledge of AI and digital tools relevant to health economics, including familiarity with data analytics platforms and digital research tools; demonstrated willingness to develop proficiency with new AI-enabled solutions to support HEOR research and evidence generation

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video ( and check out our Diversity Equity and Inclusion actions at sanofi.com ( !

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$148,500.00 - $214,500.00

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK ( .

We are an R&D driven, AI-powered biopharma company committed to improving people's lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people's lives.

We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world.

Discover more about us visiting or via our movie We are Sanofi (

Start a career that makes a difference.

Reinvention is in our DNA. It's what drove our evolution from a small French enterprise to one of the world's leading biopharma companies. Whether it's using AI to shorten drug-discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities.

This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people's lives.