Lead Local Operations Manager - Solid Tumor Oncology (1 of 2 Openings)

Job Function R&D Operations Job Sub Function Clinical Trial Project Management Job Category Professional All Job Posting Locations Remote (US), Spring House, Pennsylvania, United States of America Purpose The Lead Local Operations Manager (LOM) is a senior operational leader accountable for US country level site performance, operational strategy, and delivery across the end-to-end clinical trial lifecycle. The Lead LOM serves as the US operational nexus for assigned trials, coordinating Local Operations Managers, resolving complex escalations, and integrating country level operational insights into global trial planning and execution. The role ensures strong alignment between site level execution and global trial objectives, driving delivery against key operational KPIs related to feasibility, startup, enrollment, data quality, compliance, and closeout. You Will Be Responsible For Owns US site level operational delivery for assigned sites. Leads and coordinates local trial team activities in compliance with SOPs, other procedural documents, and applicable regulations. Leads local project planning activities to meet recruitment targets and deliver high quality data on time and within study budget, including development of local trial specific procedures and tools, recruitment planning, contingency and risk management, and budget forecasting. Provides leadership oversight and mentoring support to other local operations managers assigned to the trial or program. Shapes US trial operational strategy and integrates site insights into global feasibility and startup planning. Serves as the primary US operational interface to global trial leadership. Monitors country level operational KPIs and identifies systemic risks and mitigation strategies. Acts as escalation point for complex site contracting, operational, and recruitment issues. Represents US local operations at investigator and/or study coordinator site meetings and key governance forums. Acts as subject matter expert for assigned protocols and develops strong therapeutic knowledge to support roles and responsibilities. May represent Oncology Site Enablement on cross functional teams. Elevates US site insights to inform global decision‑making and continuous improvement. 10% travel is expected. Expected to assume additional responsibilities or special initiatives such as “Champion” or “Subject Matter Expert” and to represent the functional area or lead country, Delivery Unit, and global level process initiatives, as required. Qualifications / Requirements A minimum of a bachelor’s degree in Life Sciences, Nursing, Pharmacy, or related scientific discipline (or equivalent experience) is required; advanced scientific or clinical degrees are an advantage. Typically, a minimum of 4 years of experience in clinical trial operations, trial management, site management, or clinical monitoring, including significant experience in complex, high‑priority, or multi‑site trials. Demonstrated experience in oncology trial operations is strongly preferred. In‑depth understanding of the clinical development process and end‑to‑end trial delivery, with demonstrated expertise in feasibility, startup strategy, enrollment execution, quality oversight, and closeout. Strong and applied knowledge of GCP, regulatory requirements, inspection readiness, and compliance management, with experience supporting audits and regulatory inspections. Demonstrated leadership experience, including coaching, mentoring, and guiding other Local Operations Managers or site‑facing roles in a player‑coach capacity. Proven ability to lead through influence, resolve escalations, and drive alignment across cross‑functional and global trial teams. Experience shaping or contributing to country‑level or trial‑level operational strategy, including site selection, enrollment forecasting, and risk mitigation planning. Strong analytical skills with the ability to interpret country‑ and site‑level KPIs, identify systemic risks, and implement corrective actions. Excellent written and verbal communication skills in both the local country language and English, with demonstrated ability to represent the country or region in global forums. Willingness to travel up to 10% as required, including overnight stays and participation in investigator meetings and key trial governance meetings. Demonstrated flexibility, resilience, and ability to operate effectively in a highly complex, fast‑changing clinical development environment. Benefits Vacation –120 hours per calendar year Sick time – 40 hours per calendar year (48 hours if residing in Colorado, 56 hours if residing in Washington) Holiday pay, including Floating Holidays – 13 days per calendar year Work, Personal and Family Time – up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year Caregiver Leave – 80 hours in a 52‑week rolling period (10 days) Volunteer Leave – 32 hours per calendar year Military Spouse Time‑Off – 80 hours per calendar year For additional general information on company benefits, please visit Compensation The anticipated base pay range for this position in the US is $109,000 – $174,800. Equal Opportunity Employer Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. Johnson & Johnson actively seeks qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants should contact us via Internal employees should contact AskGS to be directed to your accommodation resource. Required Skills Preferred Skills Analytical Reasoning, Clinical Research and Regulations, Clinical Trial Designs, Clinical Trial Management Systems (CTMS), Clinical Trials, Communication, Data Savvy, Laboratory Operations, Organizing, Problem Solving, Productivity Planning, Professional Ethics, Project Integration Management, Quality Assurance (QA), Regulatory Compliance, Research and Development, Research Ethics, Standard Operating Procedure (SOP) This job posting is anticipated to close on May 20th, 2026. #J-18808-Ljbffr Johnson & Johnson Innovative Medicine