Laboratory Technologist

Performs advanced molecular biology and genetics techniques and procedures in a CLIA/CAP clinical molecular diagnostic laboratory. Primary duties will include DNA/RNA extraction, sequencing and genotyping of human DNA/RNA samples using microarrays, next-generation sequencing and real-time PCR. The laboratory is active in new test and technology development.

About Slopes Bio, Inc.

Slopes Bio enables biotech innovation and powers testing programs for enterprise clients. The Slopes Bio LabKit provides a vertically integrated platform for every step of the testing process.


Description

Performs advanced molecular biology and genetics techniques and procedures in a CLIA/CAP clinical molecular diagnostic laboratory.

Description

Primary duties will include DNA/RNA extraction, sequencing and genotyping of human DNA/RNA samples using microarrays, next-generation sequencing and real-time PCR. The laboratory is active in new test and technology development.

Must have a strong sense of responsibility and urgency, be flexible, must be detailed oriented, and have excellent organizational and communication skills. This position works as a member of an integrated laboratory team. Must be able to work independently.

Essential Duties and Responsibilities:
• Receives specimens and completes all necessary test documentation into Laboratory Information Management System (LIMS).
• Performs high complexity molecular tests offered on the clinical test menu by following the standard operating procedures (SOPs) of the laboratory.
• Performs quality control and calibrations, as required.
• Performs post-test analyses and data review to ensure accurate test result reporting.
• Recognizes problems and performs assay troubleshooting.
• Understands and follows the proficiency testing policies to comply with CAP standards.
• Regularly participates in CAP proficiency testing or other competence assessments in the laboratory and participate in periodic regulatory inspections.
• Participates in the development, validation and maintenance of high complexity clinical tests.

Additional Duties and Responsibilities:
• Train laboratory personnel as requested by laboratory management.
• Coordinate, monitor or perform additional tasks at the request of management such as assisting Quality Assurance Supervisor.
• Lead day-to-day tasks at the request of laboratory management.

Required education and skills:
• Bachelor's or master's degree in biological, chemical or medical laboratory sciences.
• Proficient in MS office applications (Word/Excel/PowerPoint)
• Ability to adapt to change efficiently.
• Knowledge of and skills in good molecular genetic laboratory practices including extraction of nucleic acids from human blood and tissues, standard and real-time PCR, and next-generation library prep and sequencing.

Preferred skills:
• Previous laboratory experience, clinical laboratory preferred.
• Next generation sequencing experience using an Illumina NextSeq 2000 or NovaSeq X instrument.
• Next generation sequencing experience using Oxford Nanopore Technologies long read protocols.
• Next generation sequencing library construction experience.
• Certification in laboratory specialty through the American Society of Clinical Pathologists (ASCP) or equivalent is a plus.
• Experience with quality control and assurance processes in clinical laboratories. Working knowledge of development of genotyping, mutation detection and sequencing assays.


Salary

$25 - $35 per hour depending on experience.

Salary


$25 - $35 per hour