Executive Director, Global Commercialization Effectiveness

Role Description

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

This is a rare and highly visible opportunity to help build something new at a pivotal moment in Revolution Medicines' growth. We are seeking an experienced and highly collaborative Executive Director, Global Commercialization Effectiveness to play a foundational role in establishing and scaling commercialization effectiveness as a core capability within the Global Commercialization organization.

This role sits within the newly formed Commercialization Effectiveness & Operations (CE&O) function and will be accountable for commercialization operations, project management, organizational effectiveness, and cross-functional integration across the commercialization organization.

You will partner closely with:

• Global Commercial Leads
• Global Medical Leads
• Global Market Access Leads
• Regional leadership teams
• Other cross-functional stakeholders

You will define and continuously evolve the Global Commercialization operating model, ensuring effective integration across:

• Commercial
• Medical Affairs
• Market Access
• Regional organizations

The role will establish scalable frameworks, planning processes, governance structures, and organizational capabilities that strengthen execution and support future growth.

Operating in a build-while-scaling environment, this leader will help shape how complex, cross-functional work gets done - bringing clarity, structure, and momentum while partnering closely with senior leaders across the organization. As the capability matures, this leader will build and lead a multidisciplinary organization spanning commercialization operations, project management, governance, planning, and organizational effectiveness.

What You’ll Do

• Serve as the primary integration leader across Global Commercial, Global Medical Affairs, Global Market Access, Regional Commercial Operations, and key corporate functions to ensure aligned planning, prioritization, and execution.
• Define and evolve the Global Commercialization operating model, establishing scalable frameworks that enable execution excellence and organizational effectiveness.
• Provide project management leadership and oversight for Global Commercialization Teams and Global Commercial Teams, ensuring alignment, accountability, and progress across strategic priorities through scalable project management capabilities and teams.
• Maintain overall accountability for execution across a portfolio of high-priority global commercial and commercialization initiatives, ensuring milestones, risks, dependencies, and decisions are effectively managed through appropriate governance, operating processes, and team leadership.
• Manage commercialization governance and planning processes, ensuring effective prioritization, resource allocation, decision-making, and escalation pathways across the commercialization organization.
• Build and scale commercialization effectiveness capabilities, including project management, operations, governance, planning, tools, dashboards, and performance management processes.
• Provide direct operational support to Global Commercial and Market Access organizations, ensuring efficient planning cycles, operational discipline, and execution consistency.
• Lead change adoption efforts related to new tools, processes, and ways of working, ensuring sustainable implementation across a global organization.
• Recruit, develop, and lead a high-performing team, creating scalable capabilities and ways of working that support the future needs of the organization.

Qualifications

• Bachelor's degree with 12+ years of relevant experience in biotech, pharmaceutical or healthcare industry, including significant experience leading complex commercial or commercialization initiatives.
• Experience supporting global commercialization organizations, including involvement in launch readiness, operational planning, or capability buildout.
• Experience working across global and regional operating models, with demonstrated ability to drive alignment across geographies.
• Demonstrated Executive Director-level capability, including defining operating models, building scalable organizational capabilities, and driving cross-functional alignment in evolving organizations.
• Strong operational leadership skills, including process design, governance, performance management, and cross-functional coordination.
• Proven success partnering with senior commercial, medical, and access leaders to enable organizational effectiveness.
• Experience building and scaling high-performing teams and organizational capabilities.
• Track record of thriving in ambiguous, fast-moving environments with a hands-on, builder mindset.
• Exceptional communication and interpersonal skills, with the ability to translate complexity into clear and actionable frameworks.
• Strong systems thinking, judgment, and a continuous improvement mindset.

Preferred Skills

• Advanced degree (MBA/MS/PhD).
• Oncology / specialty pharma commercialization experience.
• Experience building and leading commercialization operations, PMO, organizational effectiveness, or business operations functions.

Benefits

• Competitive cash compensation
• Robust equity awards
• Strong benefits
• Significant learning and development opportunities

Base Pay Salary Range

$252,000 — $315,000 USD