AI Transformation Operations Director

Job Description At Vertex, we continue to invest ina future-ready workforce whereAIhelps people strengthenexpertise, improve decision-makingand create greater impact for our people and patients.We are looking for a Director, AI TransformationOperationsto build the operatingmodelthat helpsVertex moveAI reinvention projectsfrom strategic decisions to coordinated execution. Reporting to the VP, AI Transformation, you will connect strategy, governance, and delivery acrossVertex'sAI transformation,translatingportfolio decisions into coordinated action, keepingteams aligned, and creatingthe visibility and accountability to deliver with clarity and speed. You willrunthe governance forums that guide the transformation, equippingleaders withthe information, analysis, and stakeholder input needed to maketimelydecisions. Youwillturnthose decisions into clear actions, responsibilities, and timelines, track follow-through, and keep leaders informed of progress, outstanding decisions, and areasthat needtheirsupport. Tosucceed, you will create scalable ways of working that strengthen decision-making, coordination, and follow-through,continuallyimprovinghow the Transformation Officeoperatesand the quality and pace of execution.You will model responsible use by continuously learning, applying AI to innovate your own work, and championing practices that create value. Key Duties & Responsibilities Governance planning. Maintain an integrated calendar of governance forums, decisions, milestones, andrequiredinputsso work reaches the right leaders at the right time. Governance forum coordination. Coordinate the forums that guide Vertex's AI transformation, including agendas, materials, stakeholder input, decisions, and follow-through. Decision preparation. Work across AI Transformation Strategy, Finance, Workforce Strategy & Innovation, Data Technology & Engineering, governance teams, and functional leaders to assemble the information and analysis needed fortimelydecisions. Decision follow-through. Translate governance and portfolio decisions into clear actions, responsibilities, timelines, and conditions;maintaina reliable record of commitments and open questions; and track progress through completion. Executive visibility and communications. Prepare concise, decision-oriented materials and updates that keep executiveleaders, governance forums, and key stakeholders current ondecisions, commitments,follow-through, and areas where leadership involvement is needed. Execution alignment. Keep decisions, responsibilities, actions, and timelines aligned across the teams contributing to the transformation. Transformation Office coordination. Manage the planning and follow-through needed to keep the Transformation Office focused on its priorities and connected to the broader portfolio. Scalable ways of working. Create and continually improve practical processes, tools, and templates that strengthen coordination and accountability across the transformation. AI-enabledoperations. Use AI and automation to streamline work, improve the quality and timeliness of information, and surface insights that support better decisions. Knowledge and Skills Strong knowledge of executive governance, decision processes,transformationoffice operations, and cross-functional coordination. Ability to translate strategic and portfolio decisions into clear actions, responsibilities, timelines, conditions, and follow-through. Ability to design and coordinate governance forums, including decision requirements, agendas, stakeholder input, executive materials, records, and action tracking. Strong executive-writing and synthesis skills, with the ability to turn complex information into concise, decision-oriented materials and updates. Strong organizational judgment, with the ability toanticipateinformation needs, maintain momentum, and surface areas requiring leadership involvement. Ability to create scalable processes, tools, templates, and working practices that improve coordination without adding unnecessary complexity. Strong relationship-building and influence skills across functions, including the ability toestablishshared expectations and maintain accountability without direct authority. Practical fluency with AI and automation toolsand emerging AI capabilities, with the ability to use them responsibly to streamline work, improve the timeliness and quality of information, and surface useful insights. Ability to manage multiple concurrent governance activities, decisions, actions, and stakeholder needs in a fast-moving environment. Education and Experience Bachelor's degree in business, operations, organizational management, communications, ora relatedfield - or relevant experience Advanced degree preferred. Typically requires 10 or more years of experience in enterprise operations,transformationoffice operations, executive governance, or strategic program coordination, or the equivalent combination of education and experience. Demonstrated experience coordinating governance forums and decision processes for a complex, enterprise-widetransformationor portfolio. Experience preparing concise, decision-oriented materials for senior executives and translating leadership decisions into clear actions, responsibilities, and timelines. Experiencemaintainingdisciplined follow-through across multiple functions, stakeholder groups, and concurrent priorities. Experience designing and improving scalable processes, governance routines, action-tracking practices, ormanagementinformation that strengthen coordination and accountability. Experience working across strategy, Finance, technology, workforce, governance, and business teams in a complex, matrixed organization. Pay Range $185,400 - $278,200 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status In this Hybrid-Eligible role, you can choose to be designated as:

1. Hybrid : work remotely up to two days per week; or select
2. On-Site : work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at View email address on click.appcast.io #J-18808-Ljbffr Vertex Pharmaceuticals Incorporated