Senior Director, Bioanalysis
$273.37k - $314.99kMadrigal Pharmaceuticals
Madrigal Pharmaceuticals seeks a Senior Director of Bioanalysis to lead bioanalytical strategy and oversight across clinical and nonclinical development programs for MASH therapeutics. The role provides strategic direction for external bioanalytical partnerships, ensures regulatory compliance, and drives scientific excellence across a diverse therapeutic portfolio.
Responsibilities
- Define and implement bioanalytical strategies across portfolio programs through external partnerships
- Select, manage, and evaluate CRO partners for quality, timeline, and budget performance
- Oversee assay development, qualification, validation, and sample analysis by external partners
- Develop bioanalytical strategies for multiple modalities including small molecules, siRNA, and emerging platforms
- Review and approve bioanalytical documentation ensuring regulatory compliance and data integrity
Requirements
- Advanced degree in analytical chemistry, pharmaceutical sciences, or related field (Ph.D. preferred)
- 15+ years of experience in bioanalytical sciences and drug development
- Comprehensive LC-MS/MS expertise for quantitative bioanalysis in biological matrices
- Deep knowledge of bioanalytical assay development, validation, and regulatory requirements (FDA, EMA, ICH guidelines)
- Proven leadership managing CRO partnerships and outsourced bioanalytical activities
- Experience supporting both clinical and nonclinical development programs
- Familiarity with hybridization assays, ligand binding assays, and immunoassays strongly preferred
Compensation: $273,366 - $314,989 base per year
Vacancy posted 5 days ago
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