Associate Scientist / Scientist I, Functional Genomics

Note: this is an on‑site position based in San Diego. The exact level will depend on experience. Company Overview Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome‑wide footprinting of drug‑protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first‑in‑class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein‑protein interaction inhibitors, functional activators, degraders, etc.) against undruggable targets in the oncology and immunology space. We prize scientific excellence, creativity, team players and are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where ideas and discoveries are valued and have an impact. The company has been recognized as a Top Workplace by The San Diego Union‑Tribune from 2022 to 2025. Job Summary The successful candidate will be part of the Functional Genomics department, which is devoted to identifying and characterizing novel drug targets for cancer using our functional genomics platforms. This person will play an important role in advancing our discovery platform technology and small molecule pipeline, assisting in the design and implementation of experiments aimed at identifying and validating drug targets and defining drug or gene mechanism of action. The role is ideal for a well‑rounded molecular biologist with demonstrated experience in cancer or immunology drug discovery. Essential Duties and Responsibilities Independently conduct experiments to understand drug mechanism of action Conduct large‑scale mammalian cell culture experiments and genetic perturbation studies using advanced CRISPR/Cas9 techniques Perform DNA isolation, library preparation, and next‑generation sequencing Engineer cell lines and support target and hit validation Contribute to experimental design and planning Perform and optimize cellular assays to support drug discovery efforts Summarize, analyze, and regularly present work internally Maintain exceptional scientific records of projects and experiments Education And Experience Requirements BS in a relevant scientific field with at least 7 years of hands‑on laboratory experience; MS with 5 years; or PhD with 0‑2 years of experience (industry experience preferred) Experience working as part of a goal‑oriented team Demonstrated ability to work proficiently, maintain deadlines and think critically about technical aspects of experiments Must be detail‑oriented and demonstrate excellent communication skills Experience with molecular and cellular biology techniques such as cloning, PCR, qPCR, protein isolation, western blotting Experience with multicolor flow cytometry, RNA/DNA isolation, and sequencing Extensive mammalian cell culture experience required CRISPR, shRNA, and/or siRNA experience The Following Skills Are a Plus Familiarity with genomic sequencing and functional genomic techniques Experience working on small‑molecule drug discovery programs Pay & Benefits The anticipated base salary for this position ranges from $90,000 to $120,000 depending on relevant skills, competencies, experience, and education. The position is eligible for target bonus, long‑term incentives, 401(k) retirement savings plan with company match, and a comprehensive benefits package that includes medical, dental, vision, life, and disability insurance. EEO & Employment Eligibility Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other characteristic protected by applicable federal, state, or local laws. #J-18808-Ljbffr Vividion Therapeutics, Inc.