General Ledger Accountant

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care. We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi‑disciplinary organization of scientists, engineers, and physicians and we are using the power of next‑generation sequencing (NGS), population‑scale clinical studies, and state‑of‑the‑art computer science and data science to overcome one of medicine’s greatest challenges. GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit grail.com Reporting to the Associate Director of Accounting, the GL Accountant is a key contributor in the Finance organization and will play a key role in the monthly close process, financial reporting, and accounting operations. This position will be responsible for maintaining accurate financial records, supporting internal controls, partnering with cross‑functional stakeholders. The ideal candidate is a detail‑oriented accounting professional with experience in a public company and/or public accounting environment, strong knowledge of U.S. GAAP, and the ability to thrive in a fast‑paced and evolving organization. This role is based in Menlo Park, California, and will move to Sunnyvale, California in Fall 2026. It offers a flexible work arrangement, with the ability to work from GRAIL’s office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on‑site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Menlo Park campus, Tuesdays and Thursdays are the key days where we encourage on‑site presence to engage in events and on‑site activities. Responsibilities Perform month‑end, quarter‑end and year‑end closing duties, including preparing journal entries, account reconciliations, and account analysis to ensure compliance with U.S. GAAP. Own cash and prepaid accounting across assigned accounts, including monthly reconciliation and roll‑forward schedules. Support general accrual accounting across assigned cost centers, ensuring accuracy and timely recognition. Perform balance sheet and income statement fluctuation analyses and provide meaningful explanations for significant variances. Prepare supporting documents for internal and external auditors. Execute and maintain internal controls over assigned accounting areas and support SOX compliance activities. Participate in automation and process improvements to improve efficiencies, including leveraging AI tools to reduce manual effort. Assist in maintaining regular contact and building solid working relationships with various groups to ensure a high level of customer service. Participate in cross‑functional projects and other special assignments as needed. Required Qualifications 3+ years of progressive accounting/finance experience, ideally a public accounting and private industry mix. Bachelor’s degree in accounting, finance, or related field. Excellent professional written and verbal communication and interpersonal skills required. Proficient in U.S. GAAP accounting, specifically in cash, and prepaids. Preferred Qualifications Experience with Netsuite and Coupa is preferred. Hands‑on experience with AI tools, automation, or scripting to improve accounting processes is a plus. Able to prioritize assignments, manage interruptions, and meet deadlines in a fast‑paced and growth‑oriented environment. Advanced Excel and Google Suite of products (Sheets, Docs) is a plus. Strong analytical and project management skills. Logical and critical thinking skills. Proven teamwork and collaboration skills. Experience in Life Science industries preferred. Physical Demands & Working Environment Hours and days may vary depending on operational needs. Working with dry ice may be necessary. Standing or sitting for long periods of time may be necessary. May be exposed to hazardous materials, blood specimens and instruments with moving parts, heating or freezing elements, and high‑speed centrifugation. Some lifting (up to 25 pounds) may be necessary. Ability to travel 10% as required. The expected, full‑time, annual base pay scale for this position is $95K-$117K. Actual base pay will consider skills, experience, and location. This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good‑faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time‑off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs. GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [emailprotected] if you require an accommodation to apply for an open position. GRAIL maintains a drug‑free workplace. We welcome job‑seekers from all backgrounds to join us! #J-18808-Ljbffr