Head of Sales
Helical
Own the Playbook. Win the Logos. Build the GTM.
Helical is building the AI-native lab for biology; replacing slow, costly wet lab experimentation with scalable, virtual discovery. Our platform is already deployed with leading global pharma, enabling teams to run millions of experiments in days, not years.
We have product-market traction. Now we’re scaling and looking for someone to build and lead that journey.
We’re hiring a Head of Sales to own new business and build Helical’s commercial function from the ground up.
This is a player-coach role. You’ll be responsible for closing high-value deals yourself, while also shaping how we go to market; defining the playbook, building pipeline, and laying the foundations for a high-performing commercial team.
This is not a “manage and inherit” role. This is build, sell, and scale.
Requirements
Win New Business
- Land new logos across top pharma and large biotech
- Own the full sales cycle from prospecting to close
- Navigate complex, multi-stakeholder deals with scientific buyers
- Turn initial deals into long-term, multi-program partnerships
Build the GTM Engine
- Define and execute the go-to-market strategy
- Build repeatable pipeline, qualification, and forecasting processes
- Implement AI-first sales workflows across prospecting and pipeline management
- Hire, mentor, and scale the early commercial team
Drive Strategic Growth
- Develop partnerships across pharma, tech, and research ecosystems
- Expand Helical’s footprint through high-value relationships and collaborations
Be the Market Face
- Represent Helical with credibility at key industry events and conferences
- Build relationships with decision-makers in discovery, computational biology, and AI
Who You Are
- Proven track record of closing complex enterprise deals and winning new logos
- Experience building GTM and sales functions from scratch (early-stage environments)
- Strong ability to sell into technical and scientific stakeholders
- Comfortable operating in ambiguity and owning outcomes end-to-end
- AI-first mindset—you leverage AI across your workflows to drive better results
- Deep interest in how AI is transforming drug discovery
Benefits
- Proven product already in use with top pharma
- Opportunity to shape a category-defining company at an inflection point
- High ownership, direct impact, and close collaboration with founders
- Clear trajectory to CRO / full commercial leadership
- Competitive Salary, Equity and Benefits
Vacancy posted 5 days ago
Similar jobs that could be interesting for youBased on the Head of Sales in Boston, MA vacancy
$325k - $430k
...pioneer of tomorrow—because at LivaNova, we don’t just treat conditions — we aspire to alter the course of lives.Position SummaryThe Head of Sales - Obstructive Sleep Apnea (OSA) is a newly created, senior commercial leadership role responsible for building and scaling the...SuggestedFull timeRemote workWorldwide$250k - $325k
...moves from early adopter to standard of care, and you will be the commercial architect who shapes how that happens at Elucid. As Head of Sales, you'll build and lead our US sales organization from the ground up: designing the territory model, developing the playbook,...SuggestedWork at officeLocal areaRemote work- ...Head Of Sales According to Gartner's 2025 report, ASPM (Application Security Posture Management) is a transformational technology to be adopted by 80% of organizations within 2 years. Legit Security is an ASPM leader and driving this emerging, high demand market...Suggested
Legit Security
Boston, MA1 day ago $100k - $115k
...and information content, and operate professional development programs for individuals and businesses. Job Description The Head of Sales will manage and oversee the sales within a specific portfolio within the Life Sciences Division of Informa Connect.This role will...SuggestedRemote workWork from home3 days per weekInforma
Boston, MA1 day ago- ...Job Description The Head of Sales will serve as the strategic commercial leader of M3MI, driving revenue growth, market expansion, and client engagement. The Head of Sales will have overall responsibility for the company’s global sales strategy and performance, leading...SuggestedContract workRemote workFlexible hours
Informa Connect
Boston, MA5 days ago - ...join a rocket ship and help redefine the future of AI-powered checkout, we'd love to meet you! Role at a glance As Head of Sales, you will partner with the founders and the founding sales team on go-to-market strategy, secure lighthouse customers, and build...Permanent employmentContract workRelocation packageFlexible hours
Deligo Vision Technologies Ltd
Boston, MA5 days ago - ...of follow‑on business opportunities, and in almost every case represents a major growth opportunity for our company. Summary The Head of Sales is responsible for leading revenue execution and sales organization performance at 20/20 Onsite. This role owns pipeline...
2020 On-site
Everett, MA12 hours ago $100k
...agency that just hit an inflection point. AI is reshaping our industry and we're positioned at the front of it. We have a documented sales playbook, a content engine already generating inbound leads, and two founders actively creating demand through LinkedIn, a podcast,...Permanent employmentRemote workVisa sponsorshipShift workNight shiftThe Gnar Co Inc
Boston, MA1 day ago$250k - $325k
...growing, Boston-based medical technology company that uses AI to help clinicians make better cardiovascular care decisions. As the Head of Sales, you will build and lead our US sales organization from the ground up. Your responsibilities include designing the territory...Work at officeLocal areaRemote workeLucid
Boston, MA2 days ago$228.1k - $325.85k
...intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.Purpose & Scope The GU Head of Sales will lead the US field-based sales team by developing and implementing strategies that maximize brand and patient value. This...Work at officeLocal areaRemote workWork from homeWorldwideShift work$224.9k - $404.6k
...role will play a critical part in launching Moderna’s first commercial therapeutic into the oncology market. Moderna is seeking a Head of Sales, Oncology, who will establish, lead, and scale the U.S. Oncology Sales organization and drive field strategy and execution for a...Full timeWork at officeWork from home- ...Head of Sales About the Company Premier global CX management company with presence across EMEA, Africa, India and North America. Industry Outsourcing/Offshoring Type Privately Held About the Role The Company is in search of a Head of Sales for the...
- ...Head of Regional Sales About the Company Expanding engineering company Industry Electrical/Electronic Manufacturing Type Privately Held About the Role The Company is in search of a Permanent Head of Region West Coast for its Engineering division...Permanent employment
- ...Head of Hydroelectric Sales About the Company Industrial solutions provider serving energy, infrastructure, and heavy industrial markets. Industry Machinery Type Privately Held About the Role The Company is seeking a Head of Hydroelectric Sales...Contract work
- Mirakl is actively looking for a Head of Sales, Mirakl Ads to support the rapid adoption of Mirakl Ads in the AMER region and contribute to our growth. The ideal candidate will have expertise in SaaS sales management and Retail Media. This position is available in either...Work at office
- ...Head of Inside Sales About the Company A high-growth, private equity-backed multi-site healthcare company expanding nationally. Industry Hospital & Health Care Type Privately Held, Private Equity-backed About the Role The Company is seeking a Head...Remote work
$250k - $275k
...Amazon, and Stripe, and is supported by executives & advisors from OpenAI, Google, HubSpot, and Stripe.Position Overview:As the Head of Sales Development, you will oversee the day-to-day operations of our Sales Development Representatives (SDRs), ensuring team KPIs are...Work at officeHome office- 20/20 Onsite is searching for a Head of Sales responsible for leading revenue execution and sales performance. Reporting to the CEO, this role oversees pipeline development and manages commercial growth targets. The ideal candidate will ensure alignment with the company...
$150k - $165k
...your career, while helping others along the way, come join the Broadridge team.Broadridge is seeking an entrepreneurial, growth-minded Sales Director to accelerate adoption of iJoin solutions across the recordkeeping and asset management markets. This is a high-impact...Full timeContract workLocal area$140k - $180k
...far reaching consequences, and require sensitivity, tact and a clear dedication to service. It’s about providing clarity and hope.The Sales Director is a front-line sales leader responsible for execution of the commercial sales strategy for profitable growth in geographic...$211.6k - $379.39k
...product has matured to the point where it carries serious value for larger creators and companies. What neither product has yet is a sales organization built for the segments they are moving into next.As Director of Sales, you will build it: two new teams, stood up from...Base plus commissionFull timeFor contractorsRemote work$166.51k - $203.51k
...Bring your true colors to blue. This key role will oversee a portfolio of consulting partners and will be responsible for new business sales growth both direct and through the consultants. This individual will drive sales results to increase membership and premium/revenue...Full timeLocal areaFlexible hoursShift work- NORTH AMERICA EAST SALES LEADERABOUT WIND RIVERWind River is a global leader in delivering software for mission-critical intelligent systems. For more than four decades, the company has been an innovator and pioneer, powering billions of systems that require the highest...Full timeTemporary work
- Moderna is seeking a Head of Sales, Oncology to establish and scale the U.S. Oncology Sales organization, directing field strategy and execution for a co-promotion within a joint governance model. You will partner with Marketing, Market Access, Medical, Analytics, and Alliance...
- ...Head of U.S. Sales & Operations About the Company Growth-focused industrial solutions organization expanding its U.S. presence and building a stronger national platform. Industry Wholesale Type Privately Held About the Role The Company is seeking...
$100k
...imaging, nuclear medicine, radioligand therapy, and AI-driven healthcare. This is a foundational commercial hire. You'll own the full sales cycle across a wide range of deal sizes and customer types-from closing focused product deployments with independent imaging centers...Contract workRemote workWorldwideFlexible hoursNUC S.A.I.
Boston, MA5 days ago- ...Director of Sales – Task Force As a Task Force Director of Sales, you will step into various properties to lead sales teams and provide critical short-term and long-term coverage. You'll thrive in a fast-paced, results-driven environment, quickly adapting to the unique...Temporary work
Hersha Hospitality Management
Boston, MA5 days ago $100k - $135k
...The Sales Director is a trusted member of the Sales Team reporting to the Head of Sales. This role is responsible for demonstrating the value of 829 Studios' performance marketing services to prospective clients. The Sales Director is adept at finding leads, building...Temporary workSummer workWork at officeLocal areaRemote work829 Studios
Boston, MA5 days ago- ...Job Overview We\'re seeking a Director of Sales - Compliance Services to join our vibrant team and embark on an exciting journey with us. The position will primarily work during normal business hours of 8 AM to 5 PM, Monday through Friday, but may require occasional off...Monday to Friday
ELLAB
Boston, MA4 days ago - ...Employee discounts Paid time off About the Role: Julian Eian Juel Moving and Cleaning is looking for a driven and dynamic Sales Director to lead our growth efforts nationally. This is an exciting opportunity to take ownership of our sales strategy and make a real...Work from homeFlexible hours
JULIAN EIAN JUEL MOVING AND CLEANIN
Boston, MA2 days ago
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Head of Sales. Be the first to apply!
Related searches
- head of sales Boston, MA
- director sales development Boston, MA
- sales director Boston, MA
- executive sales director Boston, MA
- managing director sales Boston, MA
- director sales training Boston, MA
- director of sales enablement Boston, MA
- head of sales enablement Boston, MA
- remote sales director Boston, MA
- director of catering sales Boston, MA