Principal Immunology Discovery Scientist
AbbVie
AbbVie is seeking a Principal Research Scientist I in Cambridge to advance checkpoint immunology programs for autoimmune and inflammatory diseases. You will lead discovery and translational research, taking concepts from target identification to candidate nomination in a collaborative, cross-functional environment. The ideal candidate combines deep immunology expertise with a drug-discovery mindset and a proven ability to mentor scientists while shaping strategy and execution across programs. #J-18808-Ljbffr AbbVie
$117k - $201.25k
...recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job... ...are searching for the best talent for a Principal Scientist, Animal Genetic Engineering - Antibody... ..., CRISPR genome engineering, B cell immunology, and antibody discovery to establish next...PrincipalContract workLocal areaImmediate start- AbbVie Inc. in Cambridge, MA seeks a Principal Research Scientist I to advance immune checkpoint programs for autoimmune... ...provide scientific leadership from target discovery through candidate nomination, combining deep immunology with a drug discovery mindset. This role...Principal
- Merck & Co., Inc. seeks a Principal Scientist (Director) to lead Immunology Biomarker strategies within Translational Clinical Biomarkers. You will shape integrated biomarker plans across discovery to late-stage programs, linking biology to clinical endpoints and decision...Principal
- AbbVie Inc. in Cambridge, MA, is seeking a Senior Scientist II to drive immune cell depletion and discovery biology. The role combines innovative research,... ...to advance therapeutic candidates. You'll perform immunological assays, apply multicolor flow cytometry, conduct...Suggested
- ...Johnson & Johnson seeks a Senior Principal Investigator to lead the design and deployment of Physical AI systems for autonomous laboratory... ...workflows, detect and recover from errors, and improve discovery outcomes. Responsibilities Design, develop, and validate...Principal
- FL94 is seeking an ambitious, creative, and talented Discovery Immunology Senior Scientist or Principal Scientist to join our research team. You will be part of the team responsible for leveraging our novel platform to develop first-in-class medicines and new chemical...
$168k - $252k
Job DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific computational methods and agentic AI systems for drug discovery. In this role, you will work across modalities with emphasis on...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week$168k - $252k
...accelerate the application of AI and agentic systems across drug discovery. Working at the intersection of Computational Drug Design,... ...) cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design, knowledge synthesis, data interpretation...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week- Pioneering Intelligence is seeking a Senior Principal Scientist to invent and build the next generation of evolutionary algorithms for autonomous... ...on Bayesian inference, reinforcement learning, optimization, and automated discovery. #J-18808-Ljbffr Pioneering IntelligencePrincipal
- Bristol Myers Squibb seeks a Principal Scientist to join the Discovery Biosciences Genomics team in Cambridge, MA. Lead multi‑omics projects using single‑cell RNA‑seq and spatial transcriptomics to advance oncology target identification, validation, and translational research...Principal
- ...Bristol Myers Squibb seeks a Principal Scientist for its Discovery BioSciences Genomics team in Cambridge, MA. The role focuses on wet lab research using multi-omics approaches—genomics, functional genomics, and spatial transcriptomics—to advance oncology drug discovery...Principal
- Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects across preclinical... ..., LLM platforms, and agent orchestration to accelerate discovery and translation within Flagship's ecosystem. #J-18808-Ljbffr...Principal
- Johnson & Johnson is seeking a Principal Scientist, Animal Genetic Engineering - Antibody Discovery, to design and engineer mouse models for advanced antibody discovery... ...role integrates mouse genetics, CRISPR, B cell immunology, and in vivo validation within our antibody...Principal
- ...We are seeking an experienced neuroscientist with strong drug discovery expertise to join our Discovery Psychiatry team. Apply drug discovery... ...discovery Provide scientific guidance and mentoring to junior scientists and research associates Qualifications Bachelor’s in a science...Principal
$208k - $286k
...exploration of novel directions. We are looking for a Senior Principal Scientist to invent and build the next generation of evolutionary... ...reinforcement learning, optimization, and automated scientific discovery. You will help define how AI systems navigate vast spaces of...Principal- Merck in Cambridge, MA seeks a Principal Scientist (Director) to lead Immunology Biomarker strategies within Translational Clinical Biomarkers. You will design and guide biomarker programs, linking drug mechanism to clinical endpoints and decision-making across development...Principal
- C4 Therapeutics, Inc. is seeking an innovative Principal Scientist, Biology (Immunology) to advance autoimmune and inflammatory disease programs using our TORPEDO platform. This lab‑based role leads projects from target identification through IND‑enabling studies, applying...Principal
$142.5k - $256.5k
...RoleModerna is seeking an accomplished and highly motivated Principal Scientist to join the Antibody Discovery team within Therapeutics Research. Therapeutics... ...’s What You’ll Need (Basic Qualifications)PhD in immunology, molecular biology, biochemistry, protein engineering...PrincipalPermanent employmentFull timeWork from home- Principal Scientist, AI-Native Discovery (Large Molecules) Johnson & Johnson Innovative Medicine is recruiting for a Principal Scientist, AI-Native Discovery (Large Molecules) to join our In Silico Drug Discovery team. This position will be located in either Spring House...PrincipalContract workRemote work
$121.28k - $202.13k
...out more: Our approach to R&D Position Summary The successful candidate will join GSK’s oligonucleotide synthesis lab as a process discovery chemist, bridging early discovery-stage chemistry with the process rigor needed to reliably deliver in vivo study material. This...PrincipalFull timeLocal area$168k - $252k
...Vertex Pharmaceuticals seeks a Senior Principal Scientist to develop and deploy agentic AI systems for drug discovery. The role combines computational expertise with scientific leadership to create AI-enabled workflows that enhance small molecule and protein therapeutic...Principal$114.1k - $211.9k
...Description Summary#LI-OnsiteInternal Title: Principal Scientist ILocation: Cambridge, MAWe are seeking... ..., Molecular Biology, Cell Biology, Immunology, or related scientific discipline with... ...supporting drug discovery, translational medicine, investigative...PrincipalFull time$168k - $252k
...artificial intelligence and agentic systems in small-molecule drug discovery. This role bridges computational drug design, data science,... ...Partner with project teams to develop and deploy AI co-scientists supporting design, analysis, and lead optimization Define scientific...Principal- Flagship Pioneering’s Pioneering Intelligence seeks a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects accelerating pharmaceutical R&D from preclinical to clinical stages. You will define pragmatic AI strategies, oversee method and...Principal
- Novartis AG in Cambridge, MA, onsite, is seeking a Principal Scientist I to drive frontier biology opportunities from concept to project initiation. You will lead hands-on lab work, interpret data, and guide projects with ambiguity, while working closely with junior researchers...Principal
$156.18k - $189.25k
...development engine, responsible for the discovery and development of novel oncology... ...research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for... ...highly motivated, experienced and talented Principal Scientist to join our Discovery...PrincipalHourly payFull timeSummer workLocal areaRemote workFlexible hours$117k - $201.25k
...Principal Scientist role in AI-native biologics discovery within Johnson & Johnson's In Silico Drug Discovery team. The position integrates artificial intelligence, computational design, and predictive modeling into therapeutic discovery programs across three U.S. locations...Principal- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Principal
$160k - $235k
...Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Boston, MA Salary Band: $160,000-$235,000 Location: Downtown Boston,... ...will work across the organization with our Discovery, Data Science, and Clin Dev teams, helping...Principal$117k - $201.25k
...Johnson & Johnson seeks a Principal Scientist to design an AI-reasoning platform for translational safety in drug discovery. The role focuses on developing multimodal AI systems and agent architectures that integrate scientific data across discovery, preclinical, clinical...Principal
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