Research Postdoctoral Fellow - Neurogenesis Research - Lefebvre Lab

Shift: Day (United States of America) Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non‑discriminatory means. A Brief Overview Under the direction/guidance of a mentor (principal investigator), assumes responsibility for a specific, on‑going research project. The experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group. This role will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. This position will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. This role also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab. A postdoctoral fellow position is available in the Lefebvre laboratory at the Children’s Hospital of Philadelphia (CHOP) Abramson Research Institute. The fellow will contribute to a project aimed at elucidating mechanisms whereby SOX5 variants cause Lamb‑Shaffer syndrome, a neurodevelopmental disorder characterized by global developmental delay, intellectual disability and autism spectrum disorder features and at testing a gene therapy candidate approach for this disorder in preclinical models. The fellow will use cutting‑edge approaches in mouse genetic models, human iPSC‑derived brain organoid models, high‑throughput ‘omics’ approaches and gene therapy strategies. Successful accomplishment of this research is anticipated to deepen fundamental scientific knowledge and to increase mechanistic understanding of neurodevelopmental diseases and our ability to treat them. It is also anticipated to help the fellow launch a promising career as an independent research investigator. Strong candidates for this position will be eager to contribute to pioneering translational research. They will have obtained an M.D. or Ph.D. degree in the last three years, will have a solid scientific research track record, including first‑author publications relevant to the project, and will have outstanding communication, organizational and interpersonal skills. Candidates should send their curriculum vitae, a description of research interests and career goals, and contact information for three or more Faculty‑level references. What you will do Conduct independent scholarly research and develop new methods and protocols Participate in project planning, recording and evaluation of data Acquire technical, lab management and grant writing skills Participate in seminars, lectures, poster sessions and presentation at national meetings Supervise junior lab members Assist with other research projects Education Qualifications Doctorate - Required Skills and Abilities Ability to wear a respirator device To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more. EEO / VEVRAA Federal Contractor | Tobacco Statement Salary Range: $20,800.00 - $110,400.00 Annually Salary ranges are shown for full‑time jobs. If you’re working part‑time, your pay will be adjusted accordingly. If you are applying for a Research Post‑Doctoral Fellow role, please refer to this link for salary guidelines (copy & paste into your browser): At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP’s Compensation and Benefits. #J-18808-Ljbffr Dormont Manufacturing Co