Clinical Research Nurse

Department of Medical Research

Position Overview:
The Clinical Research Nurse provides specialized nursing care and clinical coordination for participants enrolled in clinical trials. This role is responsible for screening, enrolling, and supporting patients throughout study participation while ensuring patient safety, protocol compliance, and adherence to regulatory requirements. The nurse serves as a key liaison between patients, investigators, and research teams, supporting both high-quality patient care and the successful execution of clinical research studies.

Key Responsibilities:
* Patient Care & Study Coordination
o Screen and enroll patients in accordance with clinical trial eligibility requirements.
o Provide direct nursing care, including phlebotomy, IV placement, EKGs, and other procedures within scope of practice.
o Monitor subjects for changes in condition, adverse events, protocol adherence, and response to interventions.
o Support patient retention by fostering a positive and compliant trial experience.
* Documentation & Compliance
o Ensure accurate, timely documentation in source records, case report forms, and sponsor electronic data capture systems.
o Collaborate with investigators and study staff to maintain compliant records and protocol tools.
o Participate in the development and maintenance of approved source documents and study materials.
* Regulatory & Protocol Management
o Assist with regulatory documentation and ensure compliance with institutional, sponsor, and IRB requirements.
o Support site initiation visits, monitoring, and audits.
o Contribute to feasibility analyses and program development with investigators.
* Recruitment & Informed Consent
o Pre-screen, recruit, and consent participants in collaboration with the Principal Investigator.
o Maintain and submit screening logs to sponsors as required.
* Team Collaboration & Training
o Educate and collaborate with ancillary staff, sub-investigators, and clinical teams regarding study requirements.
o Participate in continuous quality improvement initiatives to enhance trial performance and patient outcomes.

Hours include 8:00AM - 5:00 pm Monday - Friday, and other hours, including morning hours, prior to 8AM, late evening hours after 5PM, overnights and weekends, as required by study protocols. May also include occasional travel within a 50-mile radius of Columbia.

Bachelor's degree from an accredited Nursing School or an equivalent combination of education and experience from which comparable knowledge and abilities can be obtained is necessary.
Possession of a license to practice as a Registered Nurse in the State of Missouri is necessary.
Minimum of two years of recent nursing experience in a hospital, clinic, or similar health care setting is required.

Preferred certification in clinical research by Association of Clinical Research Professionals (ACRP) or Society of Clinical Research Associates (SOCRA)

Salary Range: $75,275.20 - $95,000.00 annually
Grade: PAT - RN4
University Title: NURSE, CLINICAL RESRCH
Internal applicants can determine their university title by accessing the Talent Profile tile in myHR.

In addition to the Online Application, please provide Resume.

Columbia offers small-town friendliness with big city features and a high quality of life for people of all ages and interests. Founded on education and known as an ideal college town, its location also makes it an attractive spot for businesses and travelers. Located on Interstate 70 and U.S. Highway 63, Columbia is right in the middle of the state and the nation. Just a couple hours' drive from St. Louis and Kansas City, Columbia is Boone County's largest population center offering big-city culture, activities, and resources with a low cost of living. Columbia is home to a variety of restaurants and entertainment venues and hosts more than a dozen festivals each year. If you want to grow your career, continue your education, raise a family, and retire, Columbia is a good place to be!

This position is eligible for University benefits. As part of your total compensation, the University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, paid time off, short- and long-term disability, paid parental leave, paid caregiver leave, and educational fee discounts for all four UM System campuses. For additional information on University benefits, please visit the Faculty & Staff Benefits website at

Equal Employment Opportunity

The University of Missouri is an Equal Opportunity Employer.

To request ADA accommodations, please call the Director of Accessibility and ADA at View phone number on click.appcast.io.