People Operations Manager

Overview

We’re partnering with a fast-growing AI company transforming the way life sciences organizations commercialize therapeutics. Backed by leading investors and working with some of the world’s largest pharmaceutical companies, the business is building cutting-edge AI applications that enable pharmaceutical marketers to launch campaigns at unprecedented speed and scale.

The team is scaling rapidly and looking for a People Operations Manager to become the operational backbone of the company. This is a unique opportunity to join a high-growth startup at an exciting stage and play a central role in shaping both the employee experience and day-to-day business operations.

This position combines People Operations, Office Management, and Executive Support in a highly collaborative, fast-paced environment. The ideal candidate is proactive, detail-oriented, highly organized, and thrives in an in-person startup culture.

Location: New York City (5 days in-office)

Hours: Monday–Thursday 9am–7pm | Friday 9am–5pm

Responsibilities

People Operations & HR

• Maintain and evolve the employee handbook, policies, and people processes
• Manage onboarding and ensure new hires have a seamless day-one experience
• Act as a trusted point of contact for employee questions, concerns, and development support
• Coordinate and manage performance review cycles and manager compliance
• Support employee engagement, retention initiatives, and company culture programs
• Lead planning and execution of the annual company retreat and internal events

Office Operations & Executive Support

• Oversee daily operations of the NYC office, including facilities, vendors, supplies, and workplace experience
• Manage complex scheduling and calendaring for the executive team across multiple time zones
• Provide administrative support including travel coordination, expense management, and research tasks
• Coordinate team meetings, offsites, and company events from planning through execution
• Manage onboarding logistics including workspace setup and equipment coordination
• Partner with finance and legal teams on contracts, invoices, and operational spend
• Identify operational inefficiencies and proactively implement scalable solutions

Requirements

• 3+ years of experience across HR, People Operations, Executive Assistant, and/or Office Management functions
• Exceptional organizational skills with strong attention to detail
• Excellent written and verbal communication skills
• Ability to build trust and work effectively across all levels of the organization
• Proactive mindset with the ability to anticipate problems and solve them independently
• High level of discretion and professionalism when handling sensitive information
• Comfortable working in a fast-paced, high-growth startup environment
• Enthusiastic about being in-office and contributing to a strong team culture

Preferred

• Experience helping scale people operations within an early-stage or rapidly growing startup